Zobrazeno 1 - 9 of 9 pro vyhledávání: '"María Inés Abasolo"'
1
3-Hydroxykynurenic acid: Physicochemical properties and fluorescence labeling
Autor: Juan C. Stockert, Juan Manuel Lázaro-Martínez, María C. García Vior, Angeles Villanueva, Albertina G. Moglioni, Maria Mercedes Blanco, María S. Shmidt, Ana Lazaro-Carrillo, Andrea Tabero, Sergio D. Ezquerra Riega, María Inés Abasolo
Publikováno v: Repositorio Institucional del Instituto Madrileño de Estudios Avanzados en Nanociencia
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Quinoline is one of the most important heterocyclic systems in life sciences. Some derivatives are normal metabolites, and others are used as antibacterial, antimalarial, and anticancer agents. In this work, we describe the synthesis, physicochemical
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bea416b00a23155871aeb032955d0b4
http://hdl.handle.net/20.500.12614/1826
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3
2D- and 3D-Quantitative Structure-Activity Relationship Studies for a Series of Phenazine N,N’-Dioxide as Antitumour Agents
Autor: María Laura Lavaggi, Mercedes González, Hugo Cerecetto, Jonathan Da Cunha, María Inés Abasolo
Publikováno v: Chemical Biology & Drug Design. 78:960-968
Hypoxic regions of tumours are associated with increased resistance to radiation and chemotherapy. Nevertheless, hypoxia has been used as a tool for specific activation of some antitumour prodrugs, named bioreductive agents. Phenazine dioxides are an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5e5beaf4d2b48a1cd40ad307489c4fa7
https://doi.org/10.1111/j.1747-0285.2011.01237.x
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4
2D- and 3D-quantitative structure-activity relationship studies for a series of phenazine N,N'-dioxide as antitumour agents
Autor: Jonathan Da, Cunha, María Laura, Lavaggi, María Inés, Abasolo, Hugo, Cerecetto, Mercedes, González
Publikováno v: Chemical biologydrug design. 78(6)
Hypoxic regions of tumours are associated with increased resistance to radiation and chemotherapy. Nevertheless, hypoxia has been used as a tool for specific activation of some antitumour prodrugs, named bioreductive agents. Phenazine dioxides are an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d177f8b10e49fb7205c68ec7c306dcd4
https://pubmed.ncbi.nlm.nih.gov/21895986
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6
ChemInform Abstract: Comparative Kinetic Studies on the Synthesis of Quinoxalinone Derivatives and Pyrido(2,3-b)pyrazinone Derivatives by the Hinsberg Reaction
Autor: Beatriz M. Fernández, María Inés Abasolo, Diana G. Bekerman
Publikováno v: ChemInform. 23
Kinetic studies on the anelation of quinoxalinone derivatives 3a-c and pyrido[2,3-b]pyrazinone derivatives 5a-c and 6a-c synthesized by the Hinsberg reaction is reported. o-Phenylenediamine or 2,3-diaminopyridine were treated with bifunctional carbon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f6cba652333f40590a1617d7e8465907
https://doi.org/10.1002/chin.199231202
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7
Comparative kinetic studies on the synthesis of quinoxalinone derivatives and pyrido[2,3-b]pyrazinone derivatives by the hinsberg reaction
Autor: Beatriz M. Fernández, María Inés Abasolo, Diana G. Bekerman
Publikováno v: Journal of Heterocyclic Chemistry. 29:129-133
Kinetic studies on the anelation of quinoxalinone derivatives 3a-c and pyrido[2,3-b]pyrazinone derivatives 5a-c and 6a-c synthesized by the Hinsberg reaction is reported. o-Phenylenediamine or 2,3-diaminopyridine were treated with bifunctional carbon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c0a0c5627b02c4fe1b25c4ade5557507
https://doi.org/10.1002/jhet.5570290123
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8
Kinetic study on the anelation of heterocycles.2.pyrido[2,3-b]pyrazine and pyrido[3,4-b]pyrazine derivatives synthesized by the hinsberg reaction
Autor: María Inés Abasolo, Fabián Atlasovich, Beatriz M. Fernández, Carlos H. Gaozza, D. E. Bianchi
Publikováno v: Journal of Heterocyclic Chemistry. 27:157-162
The regioselective synthesis of pyrido[2,3-b]- and [3,4-b]pyrazine derivatives II by the Hinsberg reaction is reported starting from 2,3 and 3,4-diaminopyridine and excess of pyruvic acid or ethyl pyruvate as reactants. Good yields (higher than 90%)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4276b3ecc2a6b974a5fcf88dc22eb6d4
https://doi.org/10.1002/jhet.5570270208
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9
4-Hydroxy-1(2H)-isoquinolone-3-carboxamides synthesis and properties
Autor: María Inés Abasolo, Isabel A. Perillo, Celia B. Schapira
Publikováno v: Journal of Heterocyclic Chemistry. 22:577-581
Reaction of some α-phthalimidoacetamides 1a-i with sodium ethoxide was carried out under drastic conditions. Compounds 1b-g afforded 4-hydroxy-1(2H)-isoquinolone-3-carboxamides 2b-g, while 1h-i afforded the acid 3a-b together with the expected isoqu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f5281763f1f34e6604cc56e211d75bb
https://doi.org/10.1002/jhet.5570220274
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