Zobrazeno 1 - 10
of 30
pro vyhledávání: '"María Gómez-Romero"'
Autor:
Natalja Kurbatova, Manik Garg, Luke Whiley, Elena Chekmeneva, Beatriz Jiménez, María Gómez-Romero, Jake Pearce, Torben Kimhofer, Ellie D’Hondt, Hilkka Soininen, Iwona Kłoszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Dag Aarsland, Alejo Nevado-Holgado, Benjamine Liu, Stuart Snowden, Petroula Proitsi, Nicholas J. Ashton, Abdul Hye, Cristina Legido-Quigley, Matthew R. Lewis, Jeremy K. Nicholson, Elaine Holmes, Alvis Brazma, Simon Lovestone
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Abstract Finding early disease markers using non-invasive and widely available methods is essential to develop a successful therapy for Alzheimer’s Disease. Few studies to date have examined urine, the most readily available biofluid. Here we repor
Externí odkaz:
https://doaj.org/article/1bd85f619d574055ba7c1fb49956bdea
Autor:
Matthew Lewis, Elena Chekmeneva, Stephane Camuzeaux, Caroline Sands, Ada Yuen, Mark David, Ash Salam, Katie Chappell, Benjamin Cooper, Gordon Haggart, Lynn Maslen, María Gómez-Romero, Verena Horneffer-van der Sluis, Gonçalo Correia, Zoltan Takats
Metabolomics utilising liquid chromatography mass spectrometry (LC-MS) offers biomedical researchers a powerful means of assessing and comparing human phenotypes via measurement of the metabolome in biological samples. Platforms for LC-MS-based globa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5452cc731aa043f0e89b2580210d2ba
https://doi.org/10.26434/chemrxiv-2022-nq9k0
https://doi.org/10.26434/chemrxiv-2022-nq9k0
Autor:
Hanns-Ulrich Marschall, Ann Smith, Fouzia Sadiq, Julian R. Marchesi, Caroline Ovadia, Konstantina Spagou, Alice Mitchell, Elena Bellafante, Natalie Santa‐Pinter, Magali Sarafian, Alvaro Perdones-Montero, Shadi Abu-Hayyeh, Peter H. Dixon, Catherine Williamson, Annika Wahlström, María Gómez-Romero, Louise C. D. Clarke, Vanya Nikolova, Julian R.F. Walters, Elaine Holmes
Publikováno v:
Hepatology (Baltimore, Md.)
Ovadia, C, Perdones-Montero, A, Spagou, K, Smith, A, Sarafian, M H, Gomez Romero, M, Bellafante, E, Clarke, L CD, Sadiq, F, Nikolova, V, Mitchell, A, Dixon, P H, Santa-Pinter, N, Wahlström, A, Abu-Hayyeh, S, Walters, J, Marschall, H-U, Holmes, E, Marchesi, J R & Williamson, C 2019, ' Enhanced microbial bile acid deconjugation and impaired ileal uptake in pregnancy repress intestinal regulation of bile acid synthesis ', Hepatology, vol. 70, no. 1, pp. 276-293 . https://doi.org/10.1002/hep.30661
Ovadia, C, Perdones-Montero, A, Spagou, K, Smith, A, Sarafian, M H, Gomez Romero, M, Bellafante, E, Clarke, L CD, Sadiq, F, Nikolova, V, Mitchell, A, Dixon, P H, Santa-Pinter, N, Wahlström, A, Abu-Hayyeh, S, Walters, J, Marschall, H-U, Holmes, E, Marchesi, J R & Williamson, C 2019, ' Enhanced microbial bile acid deconjugation and impaired ileal uptake in pregnancy repress intestinal regulation of bile acid synthesis ', Hepatology, vol. 70, no. 1, pp. 276-293 . https://doi.org/10.1002/hep.30661
Pregnancy is associated with progressive hypercholanemia, hypercholesterolemia and hypertriglyceridemia, which can result in metabolic disease in susceptible women. Gut signals modify hepatic homeostatic pathways, linking intestinal content to metabo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a4faa1f362ea02136252cd02e7421e
http://europepmc.org/articles/PMC6619257
http://europepmc.org/articles/PMC6619257
Autor:
Caroline Sands, Chioma Izzi-Engbeaya, Elena Chekmeneva, Matthew R. Lewis, Stephane Camuzeaux, Gonçalo D S Correia, Waljit S. Dhillo, Zoltan Takats, María Gómez-Romero
Publikováno v:
Analytical Chemistry
Analytical Chemistry, 2021, 93 (4), pp.1924-1933. ⟨10.1021/acs.analchem.0c03848⟩
Analytical Chemistry, 2021, 93 (4), pp.1924-1933. ⟨10.1021/acs.analchem.0c03848⟩
International audience; Liquid chromatography-mass spectrometry (LC-MS) is a powerful and widely used technique for measuring the abundance of chemical species in living systems. Its sensitivity, analytical specificity, and direct applicability to bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208ec5240c80fc2748252f86251ae994
http://hdl.handle.net/10044/1/86490
http://hdl.handle.net/10044/1/86490
Autor:
Joram M. Posma, Matthew R. Lewis, Robindra Basu Roy, Leopold D. Tientcheu, Uzochukwu Egere, María Gómez-Romero, Elaine Holmes, Nicholas J. Andreas, Beate Kampmann, Toyin Togun, Verena Horneffer-van der Sluis, Stephane Camuzeaux, Abdou K. Sillah, Beatriz Jiménez
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
We applied a metabonomic strategy to identify host biomarkers in serum to diagnose paediatric tuberculosis (TB) disease. 112 symptomatic children with presumptive TB were recruited in The Gambia and classified as bacteriologically-confirmed TB, clini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c09751fd6436b5032b81c7217a74d89
http://hdl.handle.net/10044/1/84093
http://hdl.handle.net/10044/1/84093
Autor:
Elaine Holmes, Jeremy K. Nicholson, Jeremiah Stamler, Paul Elliott, María Gómez-Romero, Gonçalo D S Correia, Queenie Chan, Elena Chekmeneva
Publikováno v:
Journal of Proteome Research
The application of metabolic phenotyping to epidemiological studies involving thousands of biofluid samples presents a challenge for the selection of analytical platforms that meet the requirements of high-throughput precision analysis and cost-effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb8cebe45369aaef59384afcd1cc8c54
https://doi.org/10.1021/acs.jproteome.8b00413
https://doi.org/10.1021/acs.jproteome.8b00413
Autor:
Farid Aboud, Alberto Fernández-Gutiérrez, Alonzo Giuseppe, Antonio Segura-Carretero, Nadia Amessis-Ouchemoukh, Salim Ouchemoukh, María Gómez-Romero
Publikováno v:
LWT - Food Science and Technology. 85:460-469
A total of 35 honey samples from different regions of Algeria were studied to determine their phenolic profiles. Phenolic compounds, products of the secondary metabolism of plants, were extracted with amberlite XAD-4 and analysed by liquid chromatogr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7b69ba58b1c60438461f8c238cbdb78
https://doi.org/10.1016/j.lwt.2016.11.084
https://doi.org/10.1016/j.lwt.2016.11.084
Autor:
Ronan Astin, Nicholas Hart, Paul L. Greenhaff, Sean Manning, Mervyn Singer, Yasmin Pasha, Mark J. W. McPhail, Rachel L. Batterham, Elaine Holmes, María Gómez-Romero, Saima Saeed, Zudin Puthucheary, Hugh Montgomery, Michael C Steiner, LD Calvert, Cristiana P. Velloso, Kenneth Smith, Despina Constantin, Lindsay M. Edwards, Stephen D. R. Harridge, Danielle E. Bear, Philip J. Atherton
Publikováno v:
Puthucheary, Z A, Astin, R, Mcphail, M J W, Saeed, S, Pasha, Y, Bear, D E, Constantin, D, Velloso, C, Manning, S, Calvert, L, Singer, M, Batterham, R L, Gomez-Romero, M, Holmes, E, Steiner, M C, Atherton, P J, Greenhaff, P, Edwards, L M, Smith, K, Harridge, S D, Hart, N & Montgomery, H E 2018, ' Metabolic phenotype of skeletal muscle in early critical illness ', Thorax, vol. 73, no. 10, pp. 926-935 . https://doi.org/10.1136/thoraxjnl-2017-211073
ObjectivesTo characterise the sketetal muscle metabolic phenotype during early critical illness.MethodsVastus lateralis muscle biopsies and serum samples (days 1 and 7) were obtained from 63 intensive care patients (59% male, 54.7±18.0 years, Acute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b7c69929b491cbdf46c1c2fbb49b3ae
https://kclpure.kcl.ac.uk/ws/files/102203354/Metabolic_phenotype_of_skeletal_PUTHUCHEARY_Firstonline6July2018_SUPP_.pdf
https://kclpure.kcl.ac.uk/ws/files/102203354/Metabolic_phenotype_of_skeletal_PUTHUCHEARY_Firstonline6July2018_SUPP_.pdf
Autor:
Zoltan Takats, Peter H. Dixon, Queenie Chan, Gonçalo D S Correia, Júlia Dénes, Nick S. Macklon, Elena Chekmeneva, Carolien M. Boomsma, Dora R. Perenyi, Jeremy K. Nicholson, Elaine Holmes, María Gómez-Romero, Yvonne E Koot, E. Want, Anisha Wijeyesekera
Publikováno v:
Analytical Methods. 7:5122-5133
An automated chip-based electrospray platform was used to develop a high-throughput nanoelectrospray high resolution mass spectrometry (nESI-HRMS) method for multiplexed parallel untargeted and targeted quantitative metabolic analysis of urine sample
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::347d9ebf2443df256595619974913fa4
https://doi.org/10.1039/c5ay00850f
https://doi.org/10.1039/c5ay00850f
Autor:
Jonathan Sidibé, H. Paul Benton, Julijana Ivanisevic, Aurélien Thomas, Jeremy K. Nicholson, Aries E. Aisporna, Matthew R. Lewis, Carlos Guijas, Duane Rinehart, J. Rafael Montenegro-Burke, Tony Teav, Linh Hoang, María Gómez-Romero, Luke Whiley, Anders Nordström, Xavier Domingo-Almenara, Gary Siuzdak
Publikováno v:
Nature methods. 15(9)
Small molecule quantitative tandem mass spectrometry analysis(1) is now widely used in life sciences and medicine. Quantification is usually accomplished by prior fragmentation of standard materials and the use of commercial software to quantitate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::534da75db8b9eb8a9857e7f82c7b0cda
https://pubmed.ncbi.nlm.nih.gov/30150755
https://pubmed.ncbi.nlm.nih.gov/30150755