Zobrazeno 1 - 10
of 105
pro vyhledávání: '"María Fernández-Velasco"'
Autor:
Sergio Sánchez-García, Rafael I. Jaén, María Fernández-Velasco, Carmen Delgado, Lisardo Boscá, Patricia Prieto
Publikováno v:
Pharmacological Research, Vol 197, Iss , Pp 106982- (2023)
In the aftermath of tissue injury or infection, an efficient resolution mechanism is crucial to allow tissue healing and preserve appropriate organ functioning. Pro-resolving bioactive lipids prevent uncontrolled inflammation and its consequences. Am
Externí odkaz:
https://doaj.org/article/8b9ec3805d9b448587ed67250e97a21f
Autor:
Roberto Lozano-Rodríguez, José Avendaño-Ortíz, Karla Montalbán-Hernández, Juan Carlos Ruiz-Rodríguez, Ricardo Ferrer, Alejandro Martín-Quirós, Charbel Maroun-Eid, Juan José González-López, Anna Fàbrega, Verónica Terrón-Arcos, María Gutiérrez-Fernández, Elisa Alonso-López, Carolina Cubillos-Zapata, María Fernández-Velasco, Rebeca Pérez de Diego, Pablo Pelegrin, Carlos García-Palenciano, Francisco J. Cueto, Carlos del Fresno, Eduardo López-Collazo
Publikováno v:
EBioMedicine, Vol 97, Iss , Pp 104841- (2023)
Summary: Background: Sepsis is associated with T-cell exhaustion, which significantly reduces patient outcomes. Therefore, targeting of immune checkpoints (ICs) is deemed necessary for effective sepsis management. Here, we evaluated the role of SIGLE
Externí odkaz:
https://doaj.org/article/3b43bccf46634fe7872802feee4227c8
Autor:
Isabel Mayoral-González, Eva M. Calderón-Sánchez, Isabel Galeano-Otero, Marta Martín-Bórnez, Encarnación Gutiérrez-Carretero, María Fernández-Velasco, Nieves Domenech, María Generosa Crespo-Leiro, Ana María Gómez, Antonio Ordóñez-Fernández, Abdelkrim Hmadcha, Tarik Smani
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 838-853 (2022)
Urocortin-2 (Ucn-2) has demonstrated cardioprotective actions against myocardial ischemia-reperfusion (I/R) injuries. Herein, we explored the protective role of Ucn-2 through microRNAs (miRNAs) post-transcriptional regulation of apoptotic and pro-fib
Externí odkaz:
https://doaj.org/article/80b1b6ec2ec24c92bf07651ea1856b7a
Autor:
José Alberto Navarro-García, Rafael Salguero-Bodes, Laura González-Lafuente, Laura Martín-Nunes, Elena Rodríguez-Sánchez, Teresa Bada-Bosch, Eduardo Hernández, Evangelina Mérida-Herrero, Manuel Praga, Jorge Solís, Fernando Arribas, Héctor Bueno, Makoto Kuro-O, María Fernández-Velasco, Luis Miguel Ruilope, Carmen Delgado, Gema Ruiz-Hurtado
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background Chronic kidney disease (CKD) is associated with increased propensity for arrhythmias. In this context, ventricular repolarization alterations have been shown to predispose to fatal arrhythmias and sudden cardiac death. Between min
Externí odkaz:
https://doaj.org/article/5f5345b79b094ecbb27361b87dbd9cf4
Autor:
Laura González-Lafuente, José Alberto Navarro-García, Ángela Valero-Almazán, Elena Rodríguez-Sánchez, Sara Vázquez-Sánchez, Elisa Mercado-García, Patricia Pineros, Jonay Poveda, María Fernández-Velasco, Makoto Kuro-O, Luis M. Ruilope, Gema Ruiz-Hurtado
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1322 (2023)
Acute kidney injury (AKI) is associated with an elevated risk of cardiovascular major events and mortality. The pathophysiological mechanisms underlying the complex cardiorenal network interaction remain unresolved. It is known that the presence of A
Externí odkaz:
https://doaj.org/article/6869b39e948f406b864bc9d8640b2cd2
Autor:
José Alberto Navarro-García, Laura González-Lafuente, María Fernández-Velasco, Luis M. Ruilope, Gema Ruiz-Hurtado
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Cardiorenal syndrome (CRS) is a complex disorder that refers to the category of acute or chronic kidney diseases that induce cardiovascular disease, and inversely, acute or chronic heart diseases that provoke kidney dysfunction. There is a close rela
Externí odkaz:
https://doaj.org/article/ac6da582782d4dc9a8681efa0f0a5d0f
Autor:
María Tamayo, Laura Martín-Nunes, María José Piedras, María Martin-Calvo, Daniel Martí-Morente, Marta Gil-Fernández, Nieves Gómez-Hurtado, María Ángeles Moro, Lisardo Bosca, María Fernández-Velasco, Carmen Delgado
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5403 (2022)
Adverse ventricular remodeling is the heart’s response to damaging stimuli and is linked to heart failure and poor prognosis. Formyl-indolo [3,2-b] carbazole (FICZ) is an endogenous ligand for the aryl hydrocarbon receptor (AhR), through which it e
Externí odkaz:
https://doaj.org/article/c00458bc5a474d5e85d567e8e4df5fe3
Autor:
Rafael I. Jaén, Sergio Sánchez-García, María Fernández-Velasco, Lisardo Boscá, Patricia Prieto
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Inflammation is an a physiological response instead an essential response of the organism to injury and its adequate resolution is essential to restore homeostasis. However, defective resolution can be the precursor of severe forms of chronic inflamm
Externí odkaz:
https://doaj.org/article/b15b3550341e444a8d79ca25e0a1fa54
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/e8f6c2a095c84de89a3d1d17f61d8a3f
Autor:
Luis Augusto Aguirre, Karla Montalbán-Hernández, José Avendaño-Ortiz, Elvira Marín, Roberto Lozano, Víctor Toledano, Laura Sánchez-Maroto, Verónica Terrón, Jaime Valentín, Elisa Pulido, José Carlos Casalvilla, Carolina Rubio, Luke Diekhorst, Fernando Laso-García, Carlos del Fresno, Ana Collazo-Lorduy, Beatriz Jiménez-Munarriz, Paloma Gómez-Campelo, Emilio Llanos-González, María Fernández-Velasco, Carlos Rodríguez-Antolín, Rebeca Pérez de Diego, Ramón Cantero-Cid, Enrique Hernádez-Jimenez, Enrique Álvarez, Rocío Rosas, Blanca dies López-Ayllón, Javier de Castro, Stefanie K. Wculek, Carolina Cubillos-Zapata, Inmaculada Ibáñez de Cáceres, Prudencio Díaz-Agero, María Gutiérrez Fernández, María Paz de Miguel, David Sancho, Leon Schulte, Rosario Perona, Cristóbal Belda-Iniesta, Lisardo Boscá, Eduardo López-Collazo
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
The ‘cancer cell fusion’ theory is controversial due to the lack of methods available to identify hybrid cells and to follow the phenomenon in patients. However, it seems to be one of the best explanations for both the origin and metastasis of pr
Externí odkaz:
https://doaj.org/article/40902723f587442ab7098a6e4d03fc9a