ATG4D role in mAtg8s delipidation and neuroprotection

Autor: Guillermo Mariño, Isaac Tamargo-Gómez, Gemma G. Martínez-García, María F. Suárez, Álvaro F. Fernández

Publikováno v: Cell Death and Differentiation

Despite the great advances in autophagy research in the last years, the specific functions of the four mammalian Atg4 proteases (ATG4A-D) remain unclear. In yeast, Atg4 mediates both Atg8 proteolytic activation, and its delipidation. However, it is n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9040c2df5586fe3bc7122032e5810dcf
https://pubmed.ncbi.nlm.nih.gov/33795848

MMP-8 deficiency increases TLR/RAGE ligands S100A8 and S100A9 and exacerbates lung inflammation during endotoxemia.

Autor: Adrián González-López, Alina Aguirre, Inés López-Alonso, Laura Amado, Aurora Astudillo, María Soledad Fernández-García, María F Suárez, Estefanía Batalla-Solís, Enrique Colado, Guillermo M Albaiceta

Publikováno v: PLoS ONE, Vol 7, Iss 6, p e39940 (2012)

Matrix metalloproteinase-8, released mainly from neutrophils, is a critical regulator of the inflammatory response by its ability to cleave multiple mediators. Herein, we report the results of a model of endotoxemia after intraperitoneal LPS injectio

Externí odkaz: https://doaj.org/article/f51f6ea0935f44d68146e82e5ea14c40

Withdrawal: Identification and characterization of human archaemetzincin-1 and -2, two novel members of a family of metalloproteases widely distributed in Archaea

Autor: Araceli, Díaz-Perales, Víctor, Quesada, Juan R, Peinado, Alejandro P, Ugalde, Jesús, Álvarez, María F, Suárez, F Xavier, Gomis-Rüth, Carlos, López-Otín

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37dd61da3eb52945533e9855312f5c36
https://europepmc.org/articles/PMC6349098/

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Autophagy couteracts weight gain, lipotoxicity and pancreatic β-cell death upon hypercaloric pro-diabetic regimens

Autor: Carlos López-Otín, Francesca Castoldi, Elena Sierra-Filardi, Federico Pietrocola, Clea Bárcena, Gemma G. Martínez-García, Guido Kroemer, Lorena Esteban, Álvaro F. Fernández, María F. Suárez, Guillermo Mariño, Isaac Tamargo-Gómez, Patricia Boya

Publikováno v: Cell Death and Disease
Cell Death and Disease, Nature Publishing Group, 2017, 8, pp.e2970. ⟨10.1038/cddis.2017.373⟩
Cell Death & Disease
Scopus
Cell Death and Disease, Nature Publishing Group, 2017, 8, pp.e2970. 〈10.1038/cddis.2017.373〉
RUO. Repositorio Institucional de la Universidad de Oviedo
instname

GK is supported by the Ligue contre le Cancer (équipe labelisée); Agence National de la Recherche (ANR); Association pour la recherche sur le cancer (ARC); Cancéropôle Ile-de-France; Institut National du Cancer (INCa); Fondation Bettencourt-Schue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6070a863b1595d0f5a5e166c1205ec35
https://hal.sorbonne-universite.fr/hal-01592941