Zobrazeno 1 - 10 of 20 pro vyhledávání: '"María F. Mercogliano"'
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Akademický článek
Halting ErbB-2 isoforms retrograde transport to the nucleus as a new theragnostic approach for triple-negative breast cancer
Autor: Santiago Madera, Franco Izzo, María F. Chervo, Agustina Dupont, Violeta A. Chiauzzi, Sofia Bruni, Ezequiel Petrillo, Sharon S. Merin, Mara De Martino, Diego Montero, Claudio Levit, Gabriel Lebersztein, Fabiana Anfuso, Agustina Roldán Deamicis, María F. Mercogliano, Cecilia J. Proietti, Roxana Schillaci, Patricia V. Elizalde, Rosalía I. Cordo Russo
Publikováno v: Cell Death and Disease, Vol 13, Iss 5, Pp 1-14 (2022)
Abstract Triple-negative breast cancer (TNBC) is clinically defined by the absence of estrogen and progesterone receptors and the lack of membrane overexpression or gene amplification of receptor tyrosine kinase ErbB-2/HER2. Due to TNBC heterogeneity
Externí odkaz: https://doaj.org/article/c5cf687b8b084672a59b0ffb44e8ef9e
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3
Akademický článek
Expanding spectrum, intrafamilial diversity, and therapeutic challenges from 15 patients with heterozygous CARD11-associated diseases: A single center experience
Autor: Luciano Urdinez, Lorenzo Erra, Alejandro M. Palma, María F. Mercogliano, Julieta Belén Fernandez, Emma Prieto, Verónica Goris, Andrea Bernasconi, Marianela Sanz, Mariana Villa, Carolina Bouso, Lucia Caputi, Belen Quesada, Daniel Solis, Anabel Aguirre Bruzzo, Maria Martha Katsicas, Laura Galluzzo, Christian Weyersberg, Marcela Bocian, Maria Marta Bujan, Matías Oleastro, María B. Almejun, Silvia Danielian
Publikováno v: Frontiers in Immunology, Vol 13 (2022)
CARD11-associated diseases are monogenic inborn errors of immunity involving immunodeficiency, predisposition to malignancy and immune dysregulation such as lymphoproliferation, inflammation, atopic and autoimmune manifestations. Defects in CARD11 ca
Externí odkaz: https://doaj.org/article/75447857ce834becba913f9b9a7c680e
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4
Akademický článek
Blockade of Stat3 oncogene addiction induces cellular senescence and reveals a cell-nonautonomous activity suitable for cancer immunotherapy
Autor: Mara De Martino, Mercedes Tkach, Sofía Bruni, Darío Rocha, María F. Mercogliano, Mauro E. Cenciarini, María F. Chervo, Cecilia J. Proietti, Florent Dingli, Damarys Loew, Elmer A. Fernández, Patricia V. Elizalde, Eliane Piaggio, Roxana Schillaci
Publikováno v: OncoImmunology, Vol 9, Iss 1 (2020)
Stat3 is constitutively activated in several tumor types and plays an essential role in maintaining their malignant phenotype and immunosupression. To take advantage of the promising antitumor activity of Stat3 targeting, it is vital to understand th
Externí odkaz: https://doaj.org/article/304761e6292046bdad547449605fff86
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5
Akademický článek
Invasive micropapillary carcinoma of the breast overexpresses MUC4 and is associated with poor outcome to adjuvant trastuzumab in HER2-positive breast cancer
Autor: María F. Mercogliano, Gloria Inurrigarro, Mara De Martino, Leandro Venturutti, Martín A. Rivas, Rosalía Cordo-Russo, Cecilia J. Proietti, Elmer A. Fernández, Isabel Frahm, Sabrina Barchuk, Daniel H. Allemand, Silvina Figurelli, Ernesto Gil Deza, Sandra Ares, Felipe G. Gercovich, Eduardo Cortese, Matías Amasino, Pablo Guzmán, Juan C. Roa, Patricia V. Elizalde, Roxana Schillaci
Publikováno v: BMC Cancer, Vol 17, Iss 1, Pp 1-8 (2017)
Abstract Background Invasive micropapillary carcinoma of the breast (IMPC) is a histological tumor variant that occurs with low frequency characterized by an inside-out formation of tumor clusters with a pseudopapillary arrangement. IMPC is an aggres
Externí odkaz: https://doaj.org/article/58b71ec24f974724a0c1d23b8fb44294
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