Changes in liver enzymes are associated with changes in insulin resistance, inflammatory biomarkers and leptin in prepubertal children with obesity

Autor: Rosario Valle-Martos, Luis Jiménez-Reina, Ramón Cañete, Rosario Martos, Miguel Valle, María Dolores Cañete

Publikováno v: Italian Journal of Pediatrics, Vol 49, Iss 1, Pp 1-10 (2023)

Abstract Background Non-alcoholic fatty liver disease is associated with obesity. A subclinical inflammation state, endothelial dysfunction, and parameters related to metabolic syndrome (MetS), have been documented in children with obesity. We aimed

Externí odkaz: https://doaj.org/article/9936df7b59754a41a4905d51381ae12c

Evaluation of the gut microbiota after metformin intervention in children with obesity: A metagenomic study of a randomized controlled trial

Autor: Javier Caballero-Villarraso, Raúl Hoyos, Miriam Latorre, Ramón Cañete, Rocío Vázquez-Cobela, María Dolores Cañete, Alejandro Egea-Zorrilla, Gloria Bueno, Concepción M. Aguilera, Julio Plaza-Díaz, Angel Gil, Rosaura Leis, Belén Pastor-Villaescusa

Publikováno v: Digibug. Repositorio Institucional de la Universidad de Granada
instname
Biomedicine & Pharmacotherapy, Vol 134, Iss, Pp 111117-(2021)
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)

Background: Metformin, a first-line oral antidiabetic agent that has shown promising results in terms of treating childhood and adolescent obesity, might influence the composition of the gut microbiota. We aimed to evaluate whether the gut microbiota

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3dc44f2f30f8a27c60e96608aea5fc3
http://hdl.handle.net/10481/67551

Morbility, clinical data and proteomic analysis of IUGR and AGA newborns at different gestational ages

Autor: María Dolores Cañete, A. Rodríguez-Torronteras, J.L. Gómez-Chaparro, R. Cañete, M.D. Ruiz-González, Nieves Abril, Juan López-Barea

Publikováno v: Data in Brief, Vol 9, Iss C, Pp 438-447 (2016)
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Data in Brief

The data are related to the proteomic analysis of 43 newborns with intrauterine growth retardation (IUGR) and 45 newborns with appropriate weight for gestational age (AGA) carried out by separation via 2DE and analyzed by MS–TOF/TOF. All newborns w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbcc49c937f690947a43e9769c0fcb03
http://www.sciencedirect.com/science/article/pii/S2352340916305960

Identification of candidate serum biomarkers of childhood-onset growth hormone deficiency using SWATH-MS and feature selection

Autor: Isabel Ruiz-Sánchez, María Dolores Cañete, Ramón Cañete, Ignacio Ortea, Javier Caballero-Villarraso

Publikováno v: Journal of proteomics. 175

A typical clinical manifestation of growth hormone deficiency (GHD) is a short stature resulting from delayed growth, but GHD affects bone health, cardiovascular function and metabolic profile and therefore quality of life. Although early GH treatmen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee3eebfa4f55f4c97746ddff462f466b
https://pubmed.ncbi.nlm.nih.gov/29317355

Relationship between Changes in Plasma Leptin Concentrations and Plasminogen Activator Inhibitor-1 in Obese Prepubertal Children after Nine Months of Treatment

Autor: Rosario Valle, Miguel Valle Jiménez, Francisco Bermudo, Ramón Cañete, M. Mar Urbano, María Dolores Cañete, Rosario M. Morales, Rosario Martos

Publikováno v: Annals of Nutrition and Metabolism. 63:216-222

Background/Aims: The metabolic syndrome (MS) is associated with insulin resistance (IR), inappropriate fibrinolysis and high plasma leptin concentrations. The aim of this study was to quantify fibrinolysis and MS-related variables in obese prepuberta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4805a197ed9ddf975088d9927393084d
https://doi.org/10.1159/000351597