Výsledky vyhledávání - "María Canive"

Akademický článek

MicroRNAs modulate immunological and inflammatory responses in Holstein cattle naturally infected with Mycobacterium avium subsp. paratuberculosis

Autor: Gerard Badia-Bringué, María Canive, Cristina Blanco-Vázquez, Rosana Torremocha, Susana Ovalle, Ricardo Ramos-Ruiz, Rosa Casais, Marta Alonso-Hearn

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)

Abstract MicroRNAs (miRNAs) regulate the post-transcriptional expression of genes by binding to their target mRNAs. In this study, whole miRNA sequencing was used to compare the expression of miRNAs in ileocecal valve (ICV) and peripheral blood (PB)

Externí odkaz: https://doaj.org/article/906132703b3a4f849252885370019927

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Akademický článek

Genome-Wide Association Study Reveals Quantitative Trait Loci and Candidate Genes Associated with High Interferon-gamma Production in Holstein Cattle Naturally Infected with Mycobacterium Bovis

Autor: Gerard Badia-Bringué, María Canive, Patricia Vázquez, Joseba M. Garrido, Almudena Fernández, Ramón A. Juste, José Antonio Jiménez, Oscar González-Recio, Marta Alonso-Hearn

Publikováno v: International Journal of Molecular Sciences, Vol 25, Iss 11, p 6165 (2024)

Mycobacterium bovis (Mb) is the causative agent of bovine tuberculosis (bTb). Genetic selection aiming to identify less susceptible animals has been proposed as a complementary measure in ongoing programs toward controlling Mb infection. However, ind

Externí odkaz: https://doaj.org/article/a38737a336c44d6084551768531b1584

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Akademický článek

Control of Mycobacterium avium subsp. paratuberculosis load within infected bovine monocyte-derived macrophages is associated with host genetics

Autor: Gerard Badia-Bringué, María Canive, Marta Alonso-Hearn

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

The genetic loci influencing individual resistance to Mycobacterium avium subsp. paratuberculosis (MAP) infection are still largely unknown. In the current study, we searched for genetic loci associated with resistance to MAP infection by evaluating

Externí odkaz: https://doaj.org/article/08dff6fbf824483e9ccf0ceed7e5feea

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Akademický článek

Association between High Interferon-Gamma Production in Avian Tuberculin-Stimulated Blood from Mycobacterium avium subsp. paratuberculosis-Infected Cattle and Candidate Genes Implicated in Necroptosis

Autor: Gerard Badia-Bringué, María Canive, Patricia Vázquez, Joseba M. Garrido, Almudena Fernández, Ramón A. Juste, José Antonio Jiménez, Oscar González-Recio, Marta Alonso-Hearn

Publikováno v: Microorganisms, Vol 11, Iss 7, p 1817 (2023)

The mechanisms underlying host resistance to Mycobacterium avium subsp. paratuberculosis (MAP) infection are largely unknown. In the current study, we hypothesize that cows with an ability to produce higher levels of interferon-gamma (IFNɣ) might co

Externí odkaz: https://doaj.org/article/83dda1ec252d4a23a91a61e53f8090b9

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Akademický článek

A Genome-Wide Association Study for Tolerance to Paratuberculosis Identifies Candidate Genes Involved in DNA Packaging, DNA Damage Repair, Innate Immunity, and Pathogen Persistence

Autor: María Canive, Gerard Badia-Bringué, Patricia Vázquez, Joseba M. Garrido, Ramón A. Juste, Almudena Fernandez, Oscar González-Recio, Marta Alonso-Hearn

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Although the genetic susceptibility to diseases has been extensively studied, the genetic loci and the primary molecular and cellular mechanisms that control disease tolerance are still largely unknown. Bovine paratuberculosis (PTB) is an enteritis c

Externí odkaz: https://doaj.org/article/265104c044f9459a846158e150bf4c66

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Akademický článek

Use of ATP-Binding Cassette Subfamily A Member 13 (ABCA13) for Sensitive Detection of Focal Pathological Forms of Subclinical Bovine Paratuberculosis

Autor: Cristina Blanco-Vázquez, Marta Alonso-Hearn, Natalia Iglesias, Patricia Vázquez, Ramón A. Juste, Joseba M. Garrido, Ana Balseiro, María Canive, Javier Amado, Manuel A. Queipo, Tania Iglesias, Rosa Casais

Publikováno v: Frontiers in Veterinary Science, Vol 9 (2022)

Bovine paratuberculosis (PTB) is a chronic enteritis caused by Mycobacterium avium subspecies paratuberculosis (Map) that causes a heavy economic impact worldwide. Map infected animals can remain asymptomatic for years while transmitting the mycobact

Externí odkaz: https://doaj.org/article/d0eaae362d7f4454b846741970be2098

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Akademický článek

Detection of latent forms of Mycobacterium avium subsp. paratuberculosis infection using host biomarker-based ELISAs greatly improves paratuberculosis diagnostic sensitivity.

Autor: Cristina Blanco Vázquez, Marta Alonso-Hearn, Ramón A Juste, María Canive, Tania Iglesias, Natalia Iglesias, Javier Amado, Fernando Vicente, Ana Balseiro, Rosa Casais

Publikováno v: PLoS ONE, Vol 15, Iss 9, p e0236336 (2020)

Bovine paratuberculosis (PTB) is a chronic granulomatous enteritis, caused by Mycobacterium avium subsp. paratuberculosis (MAP), responsible for important economic losses in the dairy industry. Current diagnostic methods have low sensitivities for de

Externí odkaz: https://doaj.org/article/8fac831e33ad4123b0c2bbdf2f88e7c2

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