Výsledky vyhledávání - "María C. Gabaldón-Ull"

Akademický článek

Oral Antioxidant Vitamins and Magnesium Limit Noise-Induced Hearing Loss by Promoting Sensory Hair Cell Survival: Role of Antioxidant Enzymes and Apoptosis Genes

Autor: Juan C. Alvarado, Verónica Fuentes-Santamaría, Pedro Melgar-Rojas, María C. Gabaldón-Ull, José J. Cabanes-Sanchis, José M. Juiz

Publikováno v: Antioxidants, Vol 9, Iss 12, p 1177 (2020)

Noise induces oxidative stress in the cochlea followed by sensory cell death and hearing loss. The proof of principle that injections of antioxidant vitamins and Mg2+ prevent noise-induced hearing loss (NIHL) has been established. However, effectiven

Externí odkaz: https://doaj.org/article/d1d36d9827d54eaf8d32b799dae5191b

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Akademický článek

An Oral Combination of Vitamins A, C, E, and Mg++ Improves Auditory Thresholds in Age-Related Hearing Loss

Autor: Juan C. Alvarado, Verónica Fuentes-Santamaría, María C. Gabaldón-Ull, José M. Juiz

Publikováno v: Frontiers in Neuroscience, Vol 12 (2018)

The increasing rate of age-related hearing loss (ARHL), with its subsequent reduction in quality of life and increase in health care costs, requires new therapeutic strategies to reduce and delay its impact. The goal of this study was to determine if

Externí odkaz: https://doaj.org/article/d7561508ad3a441cb6e49c577816b5bd

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The Role of Glia in the Peripheral and Central Auditory System Following Noise Overexposure: Contribution of TNF-α and IL-1β to the Pathogenesis of Hearing Loss

Autor: Verónica Fuentes-Santamaría, Pedro Melgar-Rojas, Juan Carlos Alvarado, Josef M. Miller, José M. Juiz, María C. Gabaldón-Ull

Publikováno v: Frontiers in Neuroanatomy

Repeated noise exposure induces inflammation and cellular adaptations in the peripheral and central auditory system resulting in pathophysiology of hearing loss. In this study, we analyzed the mechanisms by which noise-induced inflammatory-related ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492e8ac6fa3b06d82746add7f45fa7b6
http://europepmc.org/articles/PMC5322242

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Upregulation of insulin-like growth factor and interleukin 1β occurs in neurons but not in glial cells in the cochlear nucleus following cochlear ablation

Autor: José M. Juiz, Verónica Fuentes-Santamaría, Juan Carlos Alvarado, María C. Gabaldón-Ull

Publikováno v: Journal of Comparative Neurology. 521:3478-3499

One of the main mechanisms used by neurons and glial cells to promote repair following brain injury is to upregulate activity-dependent molecules such as insulin-like growth factor 1 (IGF-1) and interleukin-1β (IL-1β). In the auditory system, IGF-1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::588f30b948264a37ffa426508820d324
https://doi.org/10.1002/cne.23362

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NOISE-INDUCED TOUGHENING EFFECT IN WISTAR RATS: ENHANCED AUDITORY BRAINSTEM RESPONSES ARE RELATED TO CALRETININ AND NITRIC OXIDE SYNTHASE UPREGULATION

Autor: Tania Jareño-Flores, José M. Juiz, Josef M. Miller, Juan Carlos Alvarado, María C. Gabaldón-Ull, Verónica Fuentes-Santamaría

Publikováno v: Frontiers in Neuroanatomy, Vol 10 (2016)
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Frontiers in Neuroanatomy

An appropriate conditioning noise exposure may reduce a subsequent noise-induced threshold shift. Although this “toughening” effect helps to protect the auditory system from a subsequent traumatic noise exposure, the mechanisms that regulate this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c72a7f8c80880beac383e6637342c0a
http://journal.frontiersin.org/Journal/10.3389/fnana.2016.00019/full

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Synergistic effects of free radical scavengers and cochlear vasodilators: a new otoprotective strategy for age-related hearing loss

Autor: Josef M. Miller, Pedro Melgar-Rojas, Verónica Fuentes-Santamaría, María C. Gabaldón-Ull, Juan Carlos Alvarado, José M. Juiz, María Llanos Valero

Publikováno v: Frontiers in Aging Neuroscience, Vol 7 (2015)
Frontiers in Aging Neuroscience

The growing increase in age-related hearing loss (ARHL), with its dramatic reduction in quality of life and significant increase in health care costs, is a catalyst to develop new therapeutic strategies to prevent or reduce this aging-associated cond

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66daa89808dd8ac1a979db00292c4016
https://doi.org/10.3389/fnagi.2015.00086

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Autor: María C. Gabaldón-Ull, Verónica Fuentes-Santamaría, José M. Juiz, Juan Carlos Alvarado, Diego F. López-Muñoz, Pedro Melgar-Rojas

Publikováno v: Frontiers in Neuroscience
Frontiers in Neuroscience, Vol 8 (2014)

Conductive hearing loss causes a progressive decline in cochlear activity that may result in functional and structural modifications in auditory neurons. However, whether these activity-dependent changes are accompanied by a glial response involving

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c9fff392758343a2ec44fa032217429
https://doi.org/10.3389/fnins.2014.00319

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Wistar rats: a forgotten model of age-related hearing loss

Autor: Juan Carlos Alvarado, José Luis Blanco, Verónica Fuentes-Santamaría, José M. Juiz, María C. Gabaldón-Ull

Publikováno v: Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience, Vol 6 (2014)
Frontiers in Aging Neuroscience; Vol 6

Age-related hearing loss (ARHL) is one of the most frequent sensory impairments in senescence and is a source of important socio-economic consequences. Understanding the pathological responses that occur in the central auditory pathway of patients wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc5e8871be97f6a6d40549e137b90ba7

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