Zobrazeno 1 - 10
of 16
pro vyhledávání: '"María C Arufe"'
Autor:
Jesús Mateos, Juan Fafián-Labora, Miriam Morente-López, Iván Lesende-Rodriguez, Lorenzo Monserrat, María A Ódena, Eliandre de Oliveira, Javier de Toro, María C Arufe
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205878 (2018)
Hutchinson-Gilford progeria syndrome (HGPS) is a very rare fatal disease characterized for accelerated aging. Although the causal agent, a point mutation in LMNA gene, was identified more than a decade ago, the molecular mechanisms underlying HGPS ar
Externí odkaz:
https://doaj.org/article/20f030c0b4a04c5185b412556ff0e6ea
Autor:
Miriam Morente-López, Rocio Mato-Basalo, Sergio Lucio-Gallego, Concha Gil, Mónica Carrera, Juan A. Fafián-Labora, Jesús Mateos, María C. Arufe
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Background A challenging new branch of research related to aging-associated diseases is the identification of miRNAs capable of modulating the senescence-associated secretory phenotype (SASP) which characterizes senescent cells and contribut
Externí odkaz:
https://doaj.org/article/6a497dddc75f4ff3b2e13846c4d13617
Autor:
Junquera López-Seijas, Diego Miranda-Balbuena, Alba Iglesias-Fente, Marta Sacristán-Santos, Natalia Carballo-Pedrares, María C. Arufe, Ana Rey-Rico, Juan Fafián-Labora
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 302-317 (2023)
Senescence is a process characterized by a prolonged irreversible cell-cycle arrest. The accumulation of senescent cells in tissues is related to aging and to the development of age-related diseases. Recently, gene therapy has emerged as a powerful t
Externí odkaz:
https://doaj.org/article/b6c4196608cc44c4a45f2d2b4b9cc5e7
Autor:
Juan Fafián-Labora, Miriam Morente-López, María José Sánchez-Dopico, Onno J. Arntz, Fons A. J. van de Loo, Javier De Toro, María C. Arufe
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-12 (2020)
Abstract Introduction This study assessed whether mesenchymal stem cell (MSC)-derived extracellular vesicles influenced ageing and pluripotency markers in cell cultures where they are added. Methods MSC-derived extracellular vesicles from old and you
Externí odkaz:
https://doaj.org/article/39565356b48f49d88502227fa058383f
Study of Ferroptosis Transmission by Small Extracellular Vesicles in Epithelial Ovarian Cancer Cells
Autor:
Carmen Alarcón-Veleiro, Rocío Mato-Basalo, Sergio Lucio-Gallego, Andrea Vidal-Pampín, María Quindós-Varela, Thamer Al-Qatarneh, Germán Berrecoso, Ángel Vizoso-Vázquez, María C. Arufe, Juan Fafián-Labora
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 183 (2023)
Epithelial ovarian cancer (EOC) is the most lethal gynecological cancer. The current treatment for EOC involves surgical debulking of the tumors followed by a combination of chemotherapy. While most patients achieve complete remission, many EOCs will
Externí odkaz:
https://doaj.org/article/69f55f7371ba4c22b8a59f19387490fe
Autor:
Rocío Mato-Basalo, Sergio Lucio-Gallego, Carmen Alarcón-Veleiro, Marta Sacristán-Santos, María del Pilar Miranda Quintana, Miriam Morente-López, Francisco Javier de Toro, Lucía Silva-Fernández, Alba González-Rodríguez, María C. Arufe, Juan Antonio Fafián Labora
Publikováno v:
Life, Vol 12, Iss 4, p 546 (2022)
The accumulation process of proinflammatory components in the body due to aging influences intercellular communication and is known as inflammaging. This biological mechanism relates the development of inflammation to the aging process. Recently, it
Externí odkaz:
https://doaj.org/article/609b182bd5a3424aa2f297cf3442066d
Autor:
Miriam Morente-López, Rocío Mato-Basalo, Sergio Lucio-Gallego, Lucía Silva-Fernández, Alba González-Rodríguez, Fco. Javier De Toro, Juan A. Fafián-Labora, María C. Arufe
Publikováno v:
RUC. Repositorio da Universidade da Coruña
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Osteoarthritis (OA) is closely linked to the increase in the number of senescent cells in joint tissues, and the senescence-associated secretory phenotype (SASP) is implicated in cartilage degradation. In the last decade, extracellular vesicles (EV)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea0a27f016860267cd1c3bfc8972c548
https://doi.org/10.1007/s00018-022-04580-z
https://doi.org/10.1007/s00018-022-04580-z
Autor:
Rocío Mato-Basalo, Sergio Lucio-Gallego, Carmen Alarcón-Veleiro, Marta Sacristán-Santos, María del Pilar Miranda Quintana, Miriam Morente-López, Francisco Javier de Toro, Lucía Silva-Fernández, Alba González-Rodríguez, María C. Arufe, Juan Antonio Fafián Labora
Publikováno v:
RUC. Repositorio da Universidade da Coruña
instname
instname
This article belongs to the Special Issue Extracellular Vesicles Research in Inflamm-Aging [Abstract] The accumulation process of proinflammatory components in the body due to aging influences intercellular communication and is known as inflammaging.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e75a359171c7ac531939ccfae3b2df60
http://hdl.handle.net/2183/30642
http://hdl.handle.net/2183/30642
Autor:
Paschalia Pantazi, Valeria Barreca, Dulaney L Miller, María C Arufe, Manuela Frasco, Álvaro Compañ Bertomeu, Joana Pires, Ankush Bansal, Chiara Franco, Amanda Salviano-Silva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::418b3dda9f8b1bb780b4127941789852
https://hdl.handle.net/11577/3469042
https://hdl.handle.net/11577/3469042
Autor:
Anindya Mukhopadhya, Nishant Patel, Monica Castro-Cruz, María C Arufe, Ana Patricia Tavares Moreira, Steven Botts, Marco Pirisinu, Kaylan Jackson, Andrea Carraro, Susanna Negrisolo
Publikováno v:
Journal of Extracellular Vesicles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7de0f91a0a37470ea9797c381020b5ec
https://doi.org/10.1002/jev2.12083
https://doi.org/10.1002/jev2.12083