Comparison of the 2022 and 2017 European LeukemiaNet risk classifications in a real-life cohort of the PETHEMA group

Autor: Claudia Sargas, Rosa Ayala, María J. Larráyoz, María C. Chillón, Eduardo Rodriguez-Arboli, Cristina Bilbao, Esther Prados de la Torre, David Martínez-Cuadrón, Rebeca Rodríguez-Veiga, Blanca Boluda, Cristina Gil, Teresa Bernal, Juan Bergua, Lorenzo Algarra, Mar Tormo, Pilar Martínez-Sánchez, Elena Soria, Josefina Serrano, Juan M. Alonso-Dominguez, Raimundo García, María Luz Amigo, Pilar Herrera-Puente, María J. Sayas, Esperanza Lavilla-Rubira, Joaquín Martínez-López, María J. Calasanz, Ramón García-Sanz, José A. Pérez-Simón, María T. Gómez Casares, Joaquín Sánchez-García, Eva Barragán, Pau Montesinos, PETHEMA cooperative study group

Publikováno v: Blood Cancer Journal, Vol 13, Iss 1, Pp 1-7 (2023)

Abstract Next-Generation Sequencing is needed for the accurate genetic risk stratification of acute myeloid leukemia according to European LeukemiaNet (ELN) guidelines. We validated and compared the 2022 ELN risk classification in a real-life cohort

Externí odkaz: https://doaj.org/article/922c45afad2e435b8c679c0aca4ae8f0

Management of mixed acute rejection driven by a de novo donor-specific complement-binding anti-DQB1*03:01 antibody and intraepithelial CD8 T-cells in a kidney recipient: a case report

Autor: A Rodríguez-Campón, G Tabernero, P Fraile, Francisco Boix, María C. Chillón, Ramón García-Sanz, S García-Sánchez, J Feito

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

Mixed acute rejection is a clinicopathological entity that is difficult to accurately diagnose, and so may be under-reported. Allografts are lost more often than in either humoral or cellular rejection. The diagnosis requires both histological and im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdcb249c405d41204c7ff750e1ae0f04
https://doi.org/10.1080/09674845.2021.1927308

The novel HLA-DQB1*06:03:27 allele characterised by sequence-based typing in a European bone marrow donor

Autor: María C. Chillón, Sergio García-Sánchez, Miguel Alcoceba, Luis Alberto Marín-Rubio, Francisco Boix

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

A single nucleotide substitution in exon 3 of HLA-DQB1*06:03:01 results in a new allele, HLA-DQB1*06:03:27.
Gerencia Regional de Salud de Castilla y Leon, Grant/Award Number: GRS 2080/A/19, 2019

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deaeed7ab4e71074219428fda0bfb2fc
https://pubmed.ncbi.nlm.nih.gov/33834633

Networking for advanced molecular diagnosis in acute myeloid leukemia patients is possible: the PETHEMA NGS-AML project

Autor: Pilar Martínez-Sánchez, Elena Soria, Kamila Janusz, Pau Montesinos, Claudia Sargas, Maria Jose Sayas, María Teresa Gómez-Casares, Estrella Carrillo-Cruz, Yanira Florido-Ortega, Pilar Herrera-Puente, Eva Barragán, Carmen Botella, Lisette Costilla-Barriga, Manuel Yébenes-Ramírez, María José Calasanz, María José Larrayoz, Esther Pérez-Santolalla, Victor Noriega, Raimundo García, Josefina Serrano, Teresa Bernal, Mari Luz Amigo, David Martínez-Cuadrón, Iria Vázquez, Inmaculada Rapado, Esperanza Lavilla-Rubira, Cristina Bilbao, Rosa Ayala, Inmaculada Marchante, Joaquin Sanchez-Garcia, Joaquin Martinez-Lopez, Miguel A. Sanz, María C. Chillón, José Antonio Pérez-Simón, Juan M. Alonso-Domínguez, Juan Bergua, Lorenzo Algarra, Marcos González-Díaz, Ramón García-Sanz, Mar Tormo, Marta Llop

Publikováno v: Dadun. Depósito Académico Digital de la Universidad de Navarra
Universitat Oberta de Catalunya (UOC)
HAEMATOLOGICA
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL
r-FISABIO. Repositorio Institucional de Producción Científica
Haematologica

Next-Generation Sequencing has recently been introduced to efficiently and simultaneously detect genetic variations in acute myeloid leukemia. However, its implementation in the clinical routine raises new challenges focused on the diversity of assay

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1581388c58b93358ecb145b0eb710311
https://hdl.handle.net/10171/62895

Upregulation of Dicer is more frequent in monoclonal gammopathies of undetermined significance than in multiple myeloma patients and is associated with longer survival in symptomatic myeloma patients

Autor: María E. Sarasquete, Norma C. Gutiérrez, Irena Misiewicz-Krzeminska, Bruno Paiva, María C. Chillón, Miguel Alcoceba, Ramón García-Sanz, Jesús M. Hernández, Marcos González, Jesús F. San-Miguel

Publikováno v: Haematologica, Vol 96, Iss 3 (2011)

Dicer and Drosha are key enzymes in the miRNA-processing pathway which is altered in many human cancers.We analyzed Dicer and Drosha expression levels by quantitative PCR in 151 patients with monoclonal gammopathies: 102 symptomatic myeloma patients,

Externí odkaz: https://doaj.org/article/f2e315af363d4494a18748a2e6ad2d51