Zobrazeno 1 - 10
of 38
pro vyhledávání: '"María C, Camilión de Hurtado"'
Autor:
Carolina D. Garciarena, María C. Villa-Abrille, Néstor G. Pérez, Irene L. Ennis, Horacio E. Cingolani, María C. Camilión de Hurtado, Ernesto A. Aiello
Publikováno v:
Current Cardiology Reviews. 3:149-164
In this review, the enhanced activity of the cardiac Na+/H+ exchanger is considered to be a key step in the intracellular signaling pathway leading to cardiac hypertrophy, and the inhibition of the exchanger is a pharmacological tool to prevent or re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1315bb9c59b630dc555022cc7a6bcf11
https://doi.org/10.2174/157340307780618343
https://doi.org/10.2174/157340307780618343
Autor:
Carolina D. Garciarena, Angela M. Suburo, María C. Villa-Abrille, María C. Camilión de Hurtado, Horacio E. Cingolani, Irene L. Ennis, Mariana Cornelli, María V. Correa, Alejandro Nolly, Ernesto A. Aiello, V. Torbidoni
Publikováno v:
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Universidad Nacional de La Plata
instacron:UNLP
Many effects believed to be because of angiotensin II (Ang II) are attributable to the action of endothelin (ET)-1, which is released/produced by Ang II. We investigated whether Ang II elicits its positive inotropic effect (PIE) by the action of endo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d576950b0829c7bca9531d6631faa560
https://doi.org/10.1161/01.hyp.0000208302.62399.68
https://doi.org/10.1161/01.hyp.0000208302.62399.68
Autor:
Patricio E. Morgan, Gladys E. Chiappe de Cingolani, Fernando Farias, María C. Camilión de Hurtado
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 83:397-404
Enhanced activity of Na+/H+isoform 1 (NHE-1) and the Na+-independent Cl–/HCO3–exchange (AE) is a feature of the hypertrophied myocardium in spontaneously hypertensive rats (SHR). The present study explored the possibility that sustained intracell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de60e95e547fb9868b612a70c648ffc4
https://doi.org/10.1139/y05-025
https://doi.org/10.1139/y05-025
Autor:
Joseph R. Casey, Néstor G. Pérez, Raul A Dulce, Gladys E. Chiappe, María C. Camilión de Hurtado, Horacio E. Cingolani, Patricio G. Morgan, Bernardo V. Alvarez, Irene L. Ennis
Publikováno v:
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Universidad Nacional de La Plata
instacron:UNLP
Previous work demonstrated that the slow force response (SFR) to stretch is due to the increase in calcium transients (Ca2+T) produced by an autocrine-paracrine mechanism of locally produced angiotensin II/endothelin activating Na+-H+ exchange. Altho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d377bed5bdf63df1f390a75b495e97e
https://doi.org/10.1161/01.res.0000102408.25664.01
https://doi.org/10.1161/01.res.0000102408.25664.01
Autor:
Horacio E. Cingolani, Oscar R. Rebolledo, Néstor G. Pérez, Enrique Leo Portiansky, María C. Camilión de Hurtado
Publikováno v:
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Universidad Nacional de La Plata
instacron:UNLP
We have recently reported that the inhibition of the Na+/H+ exchanger (NHE) during 1 month in spontaneously hypertensive rats (SHR) is followed by regression of cardiomyocyte hypertrophy but not of myocardial fibrosis. The aim of this study was to ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8100f065a79a66849dec81f798f45abc
https://doi.org/10.1161/01.hyp.0000051502.93374.1c
https://doi.org/10.1161/01.hyp.0000051502.93374.1c
Autor:
Joseph R. Casey, Patricio E. Morgan, Jocelyne Fujinaga, María C. Camilión de Hurtado, Cecilia Mundiña-Weilenmann, Horacio E. Cingolani, Gladys E. Chiappe de Cingolani
Publikováno v:
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Universidad Nacional de La Plata
instacron:UNLP
Objective: The aim was to examine the regulation of the cardiac Na+-independent Cl¯/HCO3¯ exchanger (AE) mRNA isoform expression in association to the enhanced AE activity in the hypertrophied myocardium of spontaneously hypertensive rats (SHR). Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6c453429551f3f11637a8e30e3c0682
https://doi.org/10.1016/s0008-6363(01)00276-0
https://doi.org/10.1016/s0008-6363(01)00276-0
Publikováno v:
Physiology. 16:88-91
An autocrine/paracrine mechanism is triggered by stretching the myocardium. This mechanism involves release of angiotensin II, release/increased formation of endothelin, activation of the Na+/H+ exchanger, increase in intracellular Na+, and the incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::211a49e07f7192b8109fc2c5d0384c7c
https://doi.org/10.1152/physiologyonline.2001.16.2.88
https://doi.org/10.1152/physiologyonline.2001.16.2.88
Publikováno v:
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Universidad Nacional de La Plata
instacron:UNLP
Intracellular pH is under strict control in myocardium; H⁺ are extruded from the cells by sodium-dependent mechanisms, mainly Na⁺ /H⁺ exchanger and Na⁺ /HCO₃⁻ symport, whereas Na⁺ -independent Cl⁻ /HCO₃⁻ exchanger extrudes bases o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7264696f0441347d2933ddc765e7f228
https://doi.org/10.1161/01.hyp.31.4.961
https://doi.org/10.1161/01.hyp.31.4.961
Publikováno v:
Circulation Research. 79:698-704
The contribution of electrogenic Na + -HCO 3 − cotransport to pH i regulation during changes in heart rate was explored in cat papillary muscles loaded with BCECF-AM in bicarbonate-free (HEPES) medium and in CO 2 /HCO 3 − -buffered medium. Stepwi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd1c4a1384d70e2b0d743d5b8e567dd0
https://doi.org/10.1161/01.res.79.4.698
https://doi.org/10.1161/01.res.79.4.698
Autor:
Irene L, Ennis, Carolina D, Garciarena, Eduardo M, Escudero, Néstor G, Pérez, Raúl A, Dulce, María C, Camilión de Hurtado, Horacio E, Cingolani
Publikováno v:
Canadian journal of physiology and pharmacology. 85(3-4)
Na+/H+ exchanger-1 (NHE-1) inhibition induces cardiac hypertrophy regression and (or) prevention in several experimental models, although the intracellular events involved remain unclarified. We aimed to determine whether the calcineurin/NFAT pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::efba2b17b0b44f694a000fb3b7d47569
https://pubmed.ncbi.nlm.nih.gov/17612638
https://pubmed.ncbi.nlm.nih.gov/17612638