Zobrazeno 1 - 10
of 24
pro vyhledávání: '"María Alejandra Gleisner"'
Autor:
María Alejandra Gleisner, Cristián Pereda, Andrés Tittarelli, Mariela Navarrete, Camila Fuentes, Ignacio Ávalos, Fabian Tempio, Juan Pablo Araya, María Inés Becker, Fermín Eduardo González, Mercedes Natalia López, Flavio Salazar-Onfray
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Immune checkpoint blocker (ICB) therapy has shown survival benefits for some patients with cancer. Nevertheless, many individuals remain refractory or acquire resistance to treatment, motivating the exploration of complementary immunothera
Externí odkaz:
https://doaj.org/article/28c908f8ce38455c8c9cfa54e97678c0
Autor:
Paula Fluxá, Daniel Rojas-Sepúlveda, María Alejandra Gleisner, Andrés Tittarelli, Pablo Villegas, Loreto Tapia, María Teresa Rivera, Mercedes Natalia López, Felipe Catán, Mario Uribe, Flavio Salazar-Onfray
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background Gallbladder cancer (GBC), although infrequent in industrialized countries, has high incidence rates in certain world regions, being a leading cause of death among elderly Chilean women. Surgery is the only effective treatment, and
Externí odkaz:
https://doaj.org/article/124a4fc0cd004b6992db791e2209fd5b
Autor:
María Alejandra Gleisner, Mariela Navarrete, Francisca Hofmann, Flavio Salazar-Onfray, Andrés Tittarelli
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Gap junctions (GJs)-mediated intercellular communications (GJICs) are connexin (Cx)-formed plasma membrane channels that allow for the passage of small molecules between adjacent cells, and are involved in several physiopathological processes, includ
Externí odkaz:
https://doaj.org/article/6dc55ede46004ed7a328e6d1023bb4ea
Autor:
Miguel Del Campo, Flavio Salazar-Onfray, Michelle L. Salazar, Javiera Villar, Mohammad Y. Alshahrani, Daniel A. Mitchell, Ignacio Ávalos, José M. Jiménez, Fabián Salazar, María Alejandra Gleisner, Augusto Manubens, Luisa Martinez-Pomares, María Inés Becker
Publikováno v:
European journal of immunologyReferences. 51(7)
Hemocyanins are used as immunomodulators in clinical applications because they induce a strong Th1-biased cell-mediated immunity, which has beneficial effects. They are multiligand glycosylated molecules with abundant and complex mannose-rich structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ed11a2d19fd5b8241a4b472cd42c180
https://pubmed.ncbi.nlm.nih.gov/33891704
https://pubmed.ncbi.nlm.nih.gov/33891704
Autor:
Cristián Pereda, María Alejandra Gleisner, Fabian Tempio, Camila Fuentes, Flavio Salazar-Onfray, Juan Pablo Araya, Fermín E. González, María Inés Becker, Mariela Navarrete, Ignacio Ávalos, Mercedes N. López, Andrés Tittarelli
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundImmune checkpoint blocker (ICB) therapy has shown survival benefits for some patients with cancer. Nevertheless, many individuals remain refractory or acquire resistance to treatment, motivating the exploration of complementary immunotherap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e95bda8786c9353ff019c9f450f9c88
https://jitc.bmj.com/content/8/2/e000999.full
https://jitc.bmj.com/content/8/2/e000999.full
Autor:
Flavio Salazar-Onfray, Mariela Navarrete, Peter J. Gebicke-Haerter, Andrés Tittarelli, María Alejandra Gleisner
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3736, p 3736 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The immunological synapse (IS) is an intercellular communication platform, organized at the contact site of two adjacent cells, where at least one is an immune cell. Functional IS formation is fundamental for the modulation of the most relevant immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad2017f0e165579585ac040a4e0b6ad
https://www.mdpi.com/1422-0067/21/10/3736
https://www.mdpi.com/1422-0067/21/10/3736
Autor:
María Alejandra Gleisner, Cristián Pereda, Juan Carlos Roa, Daniel Rojas-Sepúlveda, Fermín E. González, Iván Gallegos, Ignacio Ávalos, Mercedes N. López, Andrés Tittarelli, Paula Fluxá, Flavio Salazar-Onfray, Jean Michel Butte
Publikováno v:
Cancer Immunology, Immunotherapy
Immunotherapy based on checkpoint blockers has proven survival benefits in patients with melanoma and other malignancies. Nevertheless, a significant proportion of treated patients remains refractory, suggesting that in combination with active immuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2569400d01f5a9e36fdafcc5f69ce110
https://doi.org/10.1007/s00262-018-2157-5
https://doi.org/10.1007/s00262-018-2157-5
Autor:
Andrés Tittarelli, María Alejandra Gleisner, Israel Guerrero, Francisca Hofmann, Mariela Navarrete, Flavio Salazar-Onfray, Javiera A. Álvarez
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 18, p 4509 (2019)
Volume 20
Issue 18
International Journal of Molecular Sciences, Vol 20, Iss 18, p 4509 (2019)
Volume 20
Issue 18
Upon tumor antigen recognition, cytotoxic T lymphocytes (CTLs) and target cells form specialized supramolecular structures, called cytotoxic immunological synapses, which are required for polarized delivery of cytotoxic granules. In previous reports,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5255ab04833e3eeb444fd31a67c18617
https://pubmed.ncbi.nlm.nih.gov/31547237
https://pubmed.ncbi.nlm.nih.gov/31547237
Autor:
Camila Fuentes, Daniela Sauma, Maria Jose Fuenzalida, María Alejandra Gleisner, Yessia Hidalgo, Mario Rosemblatt, María Rosa Bono, Natalia Crisóstomo
Publikováno v:
Immunologic Research
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by increased autoantibody production that leads to multiple tissue injuries. Dendritic cells (DCs) are important orchestrators of immune responses and key components in fine-tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a2155ecb0e79f433630bc80d740e89
https://pubmed.ncbi.nlm.nih.gov/28741259
https://pubmed.ncbi.nlm.nih.gov/28741259
Autor:
María Alejandra Gleisner, Montserrat Reyes, Carolina Ortiz, Mercedes N. López, J. Silvio Gutkind, Nicolas Dutzan, Flavio Salazar-Onfray, Cristián Pereda, Vyomesh Patel, Fermín E. González
Publikováno v:
Immunology. 142:396-405
We have previously reported a novel method for the production of tumour-antigen-presenting cells (referred to as TAPCells) that are currently being used in cancer therapy, using an allogeneic melanoma-derived cell lysate (referred to as TRIMEL) as an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e7b01c15b09bc938c14bb6227cc2707
https://doi.org/10.1111/imm.12264
https://doi.org/10.1111/imm.12264