Zobrazeno 1 - 10
of 15
pro vyhledávání: '"María Adelaida, Gómez"'
Autor:
Deninson Alejandro Vargas, David J. Gregory, Roni Nitzan Koren, Dan Zilberstein, Ashton Trey Belew, Najib M. El-Sayed, María Adelaida Gómez
Publikováno v:
Frontiers in Parasitology, Vol 2 (2023)
Host cell functions that participate in the pharmacokinetics and pharmacodynamics (PK/PD) of drugs against intracellular pathogen infections are critical for drug efficacy. In this study, we investigated whether macrophage mechanisms of xenobiotic de
Externí odkaz:
https://doaj.org/article/3a3e86c308f74579b3e15cd09ab1ca59
Publikováno v:
Parasites & Vectors, Vol 15, Iss 1, Pp 1-11 (2022)
Abstract Background Colombia is ranked very high among countries with the highest numbers of endemic Leishmania species (n = 9) causing human disease. Although much effort has been devoted to generating simple and specific tools for Leishmania specie
Externí odkaz:
https://doaj.org/article/291ebb602efe49ab92666cdda36bc5c8
Publikováno v:
Wellcome Open Research, Vol 7 (2023)
Background: Obtaining high quality RNA from skin biopsies is complex due the physical composition and high content of nucleases of this tissue. This becomes particularly challenging when using compromised skin samples with necrotic, inflammed or dama
Externí odkaz:
https://doaj.org/article/4fd1e067ef6b4a02b98a14d80e00906d
Autor:
Adriana Navas, Lina Giraldo-Parra, Miguel Darío Prieto, Juliana Cabrera, María Adelaida Gómez
Publikováno v:
BMC Immunology, Vol 20, Iss 1, Pp 1-8 (2019)
Abstract Background Human peripheral blood mononuclear cells (PBMCs) are extensively used for research of immune cell functions, identification of biomarkers and development of diagnostics and therapeutics for human diseases, among others. The assump
Externí odkaz:
https://doaj.org/article/b0164ab2becc4510bc1b283b5bb8f5d6
Autor:
Mariana Rosales-Chilama, Monica Y. Oviedo, Yury K. Quintero, Olga L. Fernández, María Adelaida Gómez
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 108:555-560
The endosymbiotic Leishmania RNA virus 1 (LRV1) has been associated with severity and clinical manifestations of American tegumentary leishmaniasis caused by species of the Leishmania (Viannia) subgenus. Between and within Leishmania species, and amo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cb78f26d0a579a63b5fe6eb2fff7647
https://doi.org/10.4269/ajtmh.22-0551
https://doi.org/10.4269/ajtmh.22-0551
Autor:
Maria del Mar Castro, Alexandra Cossio, Adriana Navas, Olga Fernandez, Liliana Valderrama, Lyda Cuervo-Pardo, Ricardo Marquez-Oñate, María Adelaida Gómez, Nancy Gore Saravia
Publikováno v:
Pathogens, Vol 11, Iss 3, p 378 (2022)
Addition of the immunomodulator pentoxifylline (PTX) to antimonial treatment of mucosal leishmaniasis has shown increased efficacy. This randomized, double-blind, placebo-controlled trial evaluated whether addition of pentoxifylline to meglumine anti
Externí odkaz:
https://doaj.org/article/ad40c693575e4c2f813d66c2bd58e19d
Autor:
Deninson Alejandro Vargas, Miguel Dario Prieto, Alvaro José Martínez-Valencia, Alexandra Cossio, Karl E. V. Burgess, Richard J.S. Burchmore, María Adelaida Gómez
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Control of cutaneous leishmaniasis (CL) in the Americas is dependent on chemotherapy with parenteral pentavalent antimonials. High rates of treatment failure urge the search for predictive and prognostic markers of therapeutic responsiveness. In this
Externí odkaz:
https://doaj.org/article/8f2d52434058407c80a3373ff9012b82
Autor:
Alvaro J Martínez-Valencia, Carlos Frisherald Daza-Rivera, Mariana Rosales-Chilama, Alexandra Cossio, Elkin J Casadiego Rincón, Mayur M Desai, Nancy Gore Saravia, María Adelaida Gómez
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 7, p e0005713 (2017)
The determinants of parasite persistence or elimination after treatment and clinical resolution of cutaneous leishmaniasis (CL) are unknown. We investigated clinical and parasitological parameters associated with the presence and viability of Leishma
Externí odkaz:
https://doaj.org/article/22d38178b3bb418e974c903265adf9f9
Autor:
Martha Lucía Díaz, Karl Burgess, Richard Burchmore, María Adelaida Gómez, Sergio Alejandro Gómez-Ochoa, Luis Eduardo Echeverría, Carlos Morillo, Clara Isabel González
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 18; Pages: 10456
Díaz, M L, Burgess, K, Burchmore, R, Gómez, M A, Gómez-Ochoa, S A, Echeverría, L E, Morillo, C & González, C I 2022, ' Metabolomic profiling of end-stage heart failure secondary to chronic chagas cardiomyopathy ', International Journal of Molecular Sciences, vol. 23, no. 18, 10456 . https://doi.org/10.3390/ijms231810456
Díaz, M L, Burgess, K, Burchmore, R, Gómez, M A, Gómez-Ochoa, S A, Echeverría, L E, Morillo, C & González, C I 2022, ' Metabolomic profiling of end-stage heart failure secondary to chronic chagas cardiomyopathy ', International Journal of Molecular Sciences, vol. 23, no. 18, 10456 . https://doi.org/10.3390/ijms231810456
Chronic Chagas cardiomyopathy (CCC) is the most frequent and severe clinical form of chronic Chagas disease, representing one of the leading causes of morbidity and mortality in Latin America, and a growing global public health problem. There is curr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8281c3806e123eeb4f0c4e34aa736c1b
https://pubmed.ncbi.nlm.nih.gov/36142367
https://pubmed.ncbi.nlm.nih.gov/36142367
Publikováno v:
Wellcome Open Research. 7:249
Background: Obtaining high quality RNA from skin biopsies is complex due the physical composition and high content of nucleases of this tissue. This becomes particularly challenging when using compromised skin samples with necrotic, inflammed or dama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff08c9d8c664a2c2beb47f84f4f3328c
https://doi.org/10.12688/wellcomeopenres.18052.1
https://doi.org/10.12688/wellcomeopenres.18052.1