Localización cromosómica de los genes KMP-11 en cepas KP1(+) y KP1 (-) de Trypanosoma rangeli.

Autor: Claudia Urueña, Paola Santander, Hugo Díez, Marleny Montilla, Ignacio Zarante, María del Carmen Thomas, Manuel Carlos López, Concepción Puerta

Publikováno v: Biomédica: revista del Instituto Nacional de Salud, Vol 24, Iss 2, Pp 200-3 (2004)

En este trabajo se determinó la localización cromosómica de los genes codificantes para la proteína 11 de membrana de los kinetoplástidos en Trypanosoma rangeli. Los resultados indican que estos genes se localizan en dos cromosomas de 3.100 y 3.

Externí odkaz: https://doaj.org/article/85351623fff14aa5b82c358fc8afd473

Changes in saliva of dogs with canine leishmaniosis: A proteomic approach

Autor: José J. Cerón, Fernando Tecles, Anita Horvatić, Lorena Franco-Martínez, L. J. Bernal, Nicolas Guillemin, Vladimir Mrljak, Manuel Carlos López, Renata Barie Rafaj, Silvia Martínez-Subiela, María del Carmen Thomas, Asta Tvarijonaviciute

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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In the present study, a quantitative proteomic approach to study changes in saliva proteins associated with canine leishmaniosis (CanL) was performed. For this, canine salivary proteins were analysed and compared between dogs before (TO) and after (T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b989031c656cbdabee3b4e2fa97285
http://hdl.handle.net/10261/195623

Serum proteome of dogs at subclinical and clinical onset of canine leishmaniosis

Autor: Damián Escribano, José J. Cerón, María del Carmen Thomas, Asta Tvarijonaviciute, Fernando Tecles, Manuel Carlos López, Silvia Martínez-Subiela, L. J. Bernal, José de la Fuente, Lourdes Mateos-Hernández, Margarita Villar, Lorena Franco-Martínez

Publikováno v: Transboundary and emerging diseases
Transboundary and emerging diseases, Wiley-Blackwell, 2019, pp.1-10. ⟨10.1111/tbed.13354⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname

The objective of this study was to identify changes in serum proteome in dogs that may occur after an experimental infection at subclinical and clinical stages of canine leishmaniosis (CanL). For this purpose, canine pre‐ and post‐infection with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a8003a51e7a02b502347db6e2d585a
http://hdl.handle.net/10578/23839

Expression of inhibitory receptors and polyfunctional responses of T cells are linked to the risk of congenital transmission of T-cruzi

Autor: Bartolomé Carrilero, María del Carmen Thomas, Manuel Segovia, Manuel Carlos López, John Mario González, Paola Lasso, Adriana Egui, Concepción J. Puerta, Adriana Cuéllar

Publikováno v: PLoS Neglected Tropical Diseases, Vol 11, Iss 6, p e0005627 (2017)
PLoS Neglected Tropical Diseases
Digital.CSIC. Repositorio Institucional del CSIC
instname

Congenital T. cruzi infections involve multiple factors in which complex interactions between the parasite and the immune system of pregnant women play important roles. In this study, we used an experimental murine model of chronic infection with T.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce879a3b658d8a774304be7468c22254
http://hdl.handle.net/10261/157574

A putative Leishmania DNA polymerase theta protects the parasite against oxidative damage

Autor: Jose M. Requena, Vicente Larraga, Ana Alonso, Abel Fernández-Orgiler, María I. Martínez-Jiménez, Pedro J. Alcolea, Luis Blanco, María del Carmen Thomas

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Nucleic Acids Research

Leishmania infantum is a protozoan parasite that is phagocytized by human macrophages. The host macrophages kill the parasite by generating oxidative compounds that induce DNA damage. We have identified, purified and biochemically characterized a DNA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7bf794252396e19dadd3090420eeb0d
http://hdl.handle.net/10261/150706