Zobrazeno 1 - 10 of 76 pro vyhledávání: '"María Ángeles Arévalo"'
1
The synthetic steroid tibolone exerts sex-specific regulation of astrocyte phagocytosis under basal conditions and after an inflammatory challenge
Autor: Andrea Crespo-Castrillo, Luis-Miguel Garcia-Segura, María Ángeles Arévalo
Publikováno v: Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-14 (2020)
Journal of Neuroinflammation
Digital.CSIC. Repositorio Institucional del CSIC
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[Background]: Tibolone is a synthetic steroid used in clinical practice for the treatment of climacteric symptoms and osteoporosis. Active metabolites of tibolone, generated in target tissues, have an affinity for estrogen and androgen receptors. Ast
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4fb2649c93c524e5e1825a6bab79dab
https://doaj.org/article/41fe186e54324e9eb5c1ba040dc65fc1
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2
High-fat diet alters stress behavior, inflammatory parameters and gut microbiota in Tg APP mice in a sex-specific manner
Autor: John F. Cryan, Luis M. Garcia-Segura, Catherine Stanton, Natalia Yanguas-Casás, Andrea Crespo-Castrillo, María L. de Ceballos, Julie A. Chowen, María Ángeles Arévalo, Sonia Diaz-Pacheco, Kiera Healy, Cristina Torres
Publikováno v: Neurobiology of Disease, Vol 159, Iss, Pp 105495-(2021)
Digital.CSIC. Repositorio Institucional del CSIC
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Long-term high-fat diet (HFD) consumption commonly leads to obesity, a major health concern of western societies and a risk factor for Alzheimer's disease (AD). Both conditions present glial activation and inflammation and show sex differences in the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1562deac499122adf57f22be80968f80
https://pubmed.ncbi.nlm.nih.gov/34478848
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3
X-linked histone H3K27 demethylase Kdm6a regulates sexually dimorphic differentiation of hypothalamic neurons
Autor: María Julia Cambiasso, Camila Sosa, María Ángeles Arévalo, Lucas Ezequiel Cabrera Zapata, Luis M. Garcia-Segura, Carla D. Cisternas
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Cellular and Molecular Life Sciences
Several X-linked genes are involved in neuronal differentiation and may contribute to the generation of sex dimorphisms in the brain. Previous results showed that XX hypothalamic neurons grow faster, have longer axons, and exhibit higher expression o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a883f261fc85d82e29f46c4d1de12b58
http://hdl.handle.net/10261/258576
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4
Autophagy in Astrocytes: Importance for Metabolism
Autor: María Ángeles Arévalo, Ana Ortiz-Rodriguez
Autophagy is an essential mechanism to maintain cellular homeostasis. Besides its role in controlling the quality of cytoplasmic components, it participates in nutrient obtaining and lipid mobilization under stressful conditions. Furthermore, autopha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d5fc4e848fd43fc379cc7c370457420
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5
Estrogenic Regulation of Glia and Neuroinflammation
Autor: Natalia Yanguas-Casás, María Ángeles Arévalo, Luis M. Garcia-Segura, Andrea Crespo-Castrillo
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Estrogens are rapid and potent facilitators of synaptic plasticity in the adult brain; however, the steps that link estrogens to factors that regulate synaptic strength remain unclear. The present chapter will first review the acute effects of 17β
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee91a09e358de884f22b05f41f01363c
https://doi.org/10.1093/oso/9780190645908.003.0008
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6
SEXUALLY DIMORPHIC EFFECT OF GENISTEIN ON HYPOTHALAMIC NEURONAL DIFFERENTIATION IN VITRO
Autor: Giancarlo Panzica, Alice Farinetti, Stefano Gotti, María Ángeles Arévalo, Marilena Marraudino, Luis-Miguel Garcia-Segura
Publikováno v: International Journal of Molecular Sciences
Digital.CSIC. Repositorio Institucional del CSIC
instname
International Journal of Molecular Sciences, Vol 20, Iss 10, p 2465 (2019)
Volume 20
Issue 10
Developmental actions of estradiol in the hypothalamus are well characterized. This hormone generates sex differences in the development of hypothalamic neuronal circuits controlling neuroendocrine events, feeding, growth, reproduction and behavior.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33c326ec895b05ee1544667352981a4
http://hdl.handle.net/2318/1785944
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7
Estradiol-dependent axogenesis and Ngn3 expression are determined by XY sex chromosome complement in hypothalamic neurons
Autor: María Julia Scerbo, Carla D. Cisternas, Lucas Ezequiel Cabrera Zapata, Luis M. Garcia-Segura, Franco Rafael Mir, María Julia Cambiasso, María Ángeles Arévalo
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Hypothalamic neurons show sex differences in neuritogenesis, female neurons have longer axons and higher levels of the neuritogenic factor neurogenin 3 (Ngn3) than male neurons in vitro. Moreover, the effect of 17-ß-estradiol (E2) on axonal growth a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f97b85fc459f68f34eaf4a113f505fd2
http://hdl.handle.net/10261/220177
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8
The Contribution of Astrocyte Autophagy to Systemic Metabolism
Autor: María Ángeles Arévalo, Ana Ortiz-Rodriguez
Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 2479, p 2479 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
instname
© 2020 by the authors.
Autophagy is an essential mechanism to maintain cellular homeostasis. Besides its role in controlling the quality of cytoplasmic components, it participates in nutrient obtaining and lipid mobilization under stressful con
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a832abffe59f325338655ecea57ec657
http://hdl.handle.net/10261/207701
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9
Aging and sex: Impact on microglia phagocytosis
Autor: Natalia Yanguas-Casás, María Ángeles Arévalo, Luis M. Garcia-Segura, Andrea Crespo-Castrillo
Publikováno v: Aging Cell
Digital.CSIC. Repositorio Institucional del CSIC
instname
Microglia dysfunction and activation are important hallmarks of the aging brain and are concomitant with age‐related neurodegeneration and cognitive decline. Age‐associated changes in microglia migration and phagocytic capacity result in maladapt
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de7b41bc43ad1d7a41bd694fcdb18dd2
http://hdl.handle.net/10261/226951
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10
Akademický článek
Neonatal inhibition of androgen activity alters the programming of body weight and orexinergic peptides differentially in male and female rats
Autor: Beatriz Carrillo, Jose Manuel Fernandez-Garcia, Rocío García-Úbeda, Daniela Grassi, Ulises Primo, Noemí Blanco, Antonio Ballesta, Maria Angeles Arevalo, Paloma Collado, Helena Pinos
Publikováno v: Brain Research Bulletin, Vol 208, Iss , Pp 110898- (2024)
The involvement of androgens in the regulation of energy metabolism has been demonstrated. The main objective of the present research was to study the involvement of androgens in both the programming of energy metabolism and the regulatory peptides a
Externí odkaz: https://doaj.org/article/701c7056b9d94cad81181abc5b14af53
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