Zobrazeno 1 - 10
of 29
pro vyhledávání: '"María Álvarez-Satta"'
Autor:
María Álvarez-Satta, Mauro Lago-Docampo, Brais Bea-Mascato, Carlos Solarat, Sheila Castro-Sánchez, Søren T. Christensen, Diana Valverde
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
In this study, we aimed to evaluate the role of ALMS1 in the morphology of primary cilia and regulation of cellular signaling using a knockdown model of the hTERT-RPE1 cell line. ALMS1 depletion resulted in the formation of longer cilia, which often
Externí odkaz:
https://doaj.org/article/2d1838e82c63439eb0ccef885435e330
Autor:
Guillermo Pousada, Vincenzo Lupo, Sheila Cástro-Sánchez, María Álvarez-Satta, Ana Sánchez-Monteagudo, Adolfo Baloira, Carmen Espinós, Diana Valverde
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-19 (2017)
Abstract Pulmonary arterial hypertension is a progressive disease that causes the obstruction of precapillary pulmonary arteries and a sustained increase in pulmonary vascular resistance. The aim was to analyze functionally the variants found in the
Externí odkaz:
https://doaj.org/article/6b58ee7f72ba4e7fbad01dfe022de748
Autor:
María Álvarez-Satta, Ander Matheu
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 10 (2018)
Glioblastoma (GBM) represents the most common, malignant and lethal primary brain tumour in adults. The primary cilium is a highly conserved and dynamic organelle that protrudes from the apical surface of virtually every type of mammalian cell. There
Externí odkaz:
https://doaj.org/article/05ccca1863024277a7d2960a017a3082
Publikováno v:
Frontiers in Molecular Biosciences, Vol 4 (2017)
Bardet-Biedl syndrome (BBS) is a rare genetic disorder that belongs to the group of ciliopathies, defined as diseases caused by defects in cilia structure and/or function. The six diagnostic features considered for this syndrome include retinal dystr
Externí odkaz:
https://doaj.org/article/57eafbeb7fb041cea4df77f66577e3f5
Autor:
Sheila Castro-Sánchez, María Álvarez-Satta, Mohamed A Tohamy, Sergi Beltran, Sophia Derdak, Diana Valverde
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183081 (2017)
Ciliopathies are a group of rare disorders characterized by a high genetic and phenotypic variability, which complicates their molecular diagnosis. Hence the need to use the latest powerful approaches to faster identify the genetic defect in these pa
Externí odkaz:
https://doaj.org/article/be52a19db908499ba96242824a36929a
Autor:
Ainhoa Alberro, Ander Saenz-Antoñanzas, David Otaegui, Estefania Carrasco-Garcia, Itziar Vergara, María Álvarez-Satta, Alejandro Berna-Erro, Ander Matheu
Publikováno v:
Aging (Albany NY)
Frailty represents a state of vulnerability and increases the risk of negative health outcomes, which is becoming an important public health problem. Over recent years, multiple independent studies have attempted to identify biomarkers that can predi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00417059e7fd2b04db09a529bcdb3a2a
https://doi.org/10.18632/aging.103295
https://doi.org/10.18632/aging.103295
Autor:
Paula Aldaz, Natalia Martín-Martín, Ander Saenz-Antoñanzas, Estefania Carrasco-Garcia, María Álvarez-Satta, Alejandro Elúa-Pinin, Steven M. Pollard, Charles H. Lawrie, Manuel Moreno-Valladares, Nicolás Samprón, Jürgen Hench, Robin Lovell-Badge, Arkaitz Carracedo, Ander Matheu
Publikováno v:
Addi. Archivo Digital para la Docencia y la Investigación
instname
International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 4511
instname
International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 4511
Glioma stem cells (GSCs) are critical targets for glioma therapy. SOX9 is a transcription factor with critical roles during neurodevelopment, particularly within neural stem cells. Previous studies showed that high levels of SOX9 are associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b9f96ef826045d0be97220879c39820
Autor:
Ander Matheu, María Álvarez-Satta, Juan P Garcés, Tulio M Silva, Veronica Moncho-Amor, Manuel Moreno-Valladares
Publikováno v:
Aging and disease. 14:1013
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::086929f4c1343d87147eddc9e3851273
https://doi.org/10.14336/ad.2022.1128
https://doi.org/10.14336/ad.2022.1128
Publikováno v:
Ageing Research Reviews. 52:53-63
Brain aging is characterized by a progressive loss of tissue integrity and function as a consequence of impaired homeostasis and regeneration capacities. The primary cilium is a highly conserved organelle that projects from the cell surface in a sing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee86382347abc4a4dd7a82fd7a695d62
https://doi.org/10.1016/j.arr.2019.04.004
https://doi.org/10.1016/j.arr.2019.04.004
Autor:
Manuel Moreno-Valladares, Veronica Moncho-Amor, Iraide Bernal-Simon, Eñaut Agirre-Iturrioz, María Álvarez-Satta, Ander Matheu
Publikováno v:
International Journal of Molecular Sciences. 23:8376
We present a case report on an older woman with unspecific symptoms and predominant long-term gastrointestinal disturbances, acute overall health deterioration with loss of autonomy for daily activities, and cognitive impairment. Autopsy revealed the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60d32eb15e6bdb9f950faaabdb9ee37e
https://doi.org/10.3390/ijms23158376
https://doi.org/10.3390/ijms23158376