Inflammatory cytokines directly disrupt the bovine intestinal epithelial barrier

Autor: Charles K. Crawford, Veronica Lopez Cervantes, Mary L. Quilici, Aníbal G. Armién, María Questa, Muhammad S. Matloob, Leon D. Huynh, Aeelin Beltran, Sophie J. Karchemskiy, Katti R. Crakes, Amir Kol

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)

Abstract The small intestinal mucosa constitutes a physical barrier separating the gut lumen from sterile internal tissues. Junctional complexes between cells regulate transport across the barrier, preventing water loss and the entry of noxious molec

Externí odkaz: https://doaj.org/article/f3542f2c647842379d63501304ce83dd

Generation of iPSC line iPSC-FH2.1 in hypoxic conditions from human foreskin fibroblasts

Autor: Alejandra Guberman, Santiago Gabriel Miriuka, María Questa, Claudia Solari, Carlos Luzzani, María Elida Scassa, Gabriel Neiman, Leonardo Romorini, Carolina Bluguermann, Gustavo Sevlever

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Stem Cell Research, Vol 16, Iss 2, Pp 300-303 (2016)

Human foreskin fibroblasts were used to generate the iPSC line iPSC-FH2.1 using the EF1a-hSTEMCCA-loxP vector expressing OCT4, SOX2, c-MYC and KLF4, in 5% O2 culture conditions. Stemness was confirmed, as was pluripotency both in vivo and in vitro, i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb05d0b0ac848f08bc664da858f25614
https://www.sciencedirect.com/science/article/pii/S1873506115002068

Induced pluripotent stem cells’ self-renewal and pluripotency is maintained by a bovine granulosa cell line-conditioned medium

Autor: Claudia Solari, Noelia Losino, Santiago Gabriel Miriuka, Carlos Luzzani, Alejandra Guberman, Carolina Bluguermann, Gustavo Sevlever, María Questa, Lino Barañao, Ariel Waisman

Publikováno v: Biochemical and Biophysical Research Communications. 410:252-257

Induced pluripotent stem cells (iPSCs) are a promising type of stem cells, comparable to embryonic stem cells (ESCs) in terms of self-renew and pluripotency, generated by reprogramming somatic cells. These cells are an attractive approach to supply p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd6de0bd9ea0e0848f0750effa0779c7
https://doi.org/10.1016/j.bbrc.2011.05.126

Human embryonic stem cells and derived contractile embryoid bodies are susceptible to Coxsakievirus B infection and respond to interferon Iβ treatment

Autor: María Questa, Santiago Gabriel Miriuka, María Elida Scassa, Carolina Jaquenod De Giusti, Gabriela Pretre, Guillermo Agustín Videla Richardson, Ricardo Martín Gómez, Carolina Bluguermann, María Florencia Ferrer, Leonardo Romorini, Gustavo Sevlever

Publikováno v: SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP

We studied the susceptibility of human embryonic stem cells and derived contractile embryoid bodies from WAO9, HUES-5 and HUES-16 cell lines to Coxsackievirus B infection. After validating stem cell-like properties and cardiac phenotype, Coxsackievir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a532e841e214d749f25fd345426c104
http://sedici.unlp.edu.ar/handle/10915/84131