Sphingosine kinase 1 participates in the activation, proliferation and survival of chronic lymphocytic leukemia cells

Autor: María Belén Almejún, Mercedes Borge, Ana Colado, Esteban Enrique Elías, Enrique Podaza, Denise Risnik, Carlos Daniel De Brasi, Carmen Stanganelli, Irma Slavutsky, María Cabrejo, Horacio Fernández-Grecco, Raimundo Fernando Bezares, Santiago Cranco, Rubén Ángel Burgos, Julio César Sánchez-Ávalos, Pablo Oppezzo, Mirta Giordano, Romina Gamberale

Publikováno v: Haematologica, Vol 102, Iss 7 (2017)

Externí odkaz: https://doaj.org/article/cad2ca19b2ef4fa7a94c5b4e68b9f5f9

Clinical characteristics and evolution of hematological patients and COVID-19 in Argentina: a report from the Argentine Society of Hematology

Autor: Ana L, Basquiera, Mercedes J, García, Juliana, Martinez Rolón, Julieta, Olmedo, Julia, Laviano, Rubén, Burgos, Gastón, Caeiro, Guillermina, Remaggi, Pablo, Raña, Mariano, Paoletti, Carlos M, González, Isolda, Fernández, Astrid, Pavlovsky, Maria A, Perusini, Andrea, Rodriguez, Luciana, Guanchiale, Analia, Carvani, Laura, Mandrile, Flavia, Figueroa, Angeles, Vicente Reparaz, Patricia N, Fragapane Mathus, Gonzalo, Garate, María E, Fauque, Gustavo, Kantor, Soledad, Cruset, Jacqueline S, Gonzalez Lorch, Milagros, Szelagowski, María P, Giarini, Natalia, Oliveira, María C, García, María V, Ventriglia, Patricio H, Pereyra, Daniel R, Gutierrez, Gustavo, Kusminsky, Josefina, Troccoli, María J, Freitas, Santiago, Cranco, Natalia, Del V Sanchez, Irene, Rey, María E, Funes, Sol, Jarchum, Julian, Freue, Augusto, Miroli, Osvaldo, Guerrero, Lisa, López Ares, Reinaldo, Campestri, Victor, Bove, Graciela N, Salinas, María, Cabrejo, Jorge H, Milone, Soledad, Zabaljauregui, Daniel, Gotta, Juan Carlos, Dupont, German, Stemmelin

Publikováno v: Medicina. 81(4)

Individuals with malignancies and COVID-19 have a lower survival compared with the general population. However, the information about the impact of COVID-19 on the whole hematological population is scarce. We aimed to describe the 30th day overall su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5a7f03950ecc81218e6e8537b8d3fc73
https://pubmed.ncbi.nlm.nih.gov/34453794

Distinctive IGHV gene usage and stereotyped receptors in South American patients with chronic lymphocytic leukemia

Autor: Carmen Stanganelli, PV Campregher, Andrea Krzywinski, Raul Gabus, Adriano de Paula Sabino, Caio Perez Gomes, Priscilla Segges, Davi Coe Torres, Celso Arrais Rodrigues, Mihoko Yamamoto, María Lourdes Lopes Ferrari deChauffaille, Claudia Ortega, Camila Galvano, Rocio Hassan, Lorena Zanella, María Cabrejo, Eliana Abdelhay, Pierre-Antoine Deglesne, José Luis López, María Elena Márquez, Guillermo Dighiero, Cecilia Lang, Raimundo F. Bezares, Pablo Oppezzo, Juana Cabrera, Natalia Sotelo, Ricardo Bigni, Irma Slavutsky, Evangelina E. Agriello, Maria Tereza Cartaxo Muniz

Publikováno v: Hematological Oncology. 37:644-648

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea61ab98e27074d8fee38c41b6c8714
https://doi.org/10.1002/hon.2661

Sphingosine kinase 1 participates in the activation, proliferation and survival of chronic lymphocytic leukemia cells

Autor: Mercedes Borge, Horacio Fernández-Grecco, Irma Slavutsky, Enrique Podaza, Raimundo F. Bezares, Pablo Oppezzo, Romina Gamberale, Carmen Stanganelli, Ana Colado, Rubén Ángel Burgos, Julio César Sánchez-Ávalos, Santiago Cranco, Mirta Giordano, Carlos Daniel De Brasi, Denise Risnik, María Belén Almejún, Esteban Enrique Elías, María Cabrejo

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Sphingosine kinases (SKs) have received the most attention as important enzymes in cancer biology. They participate in the regulation of bioactive sphingolipid metabolism by producing sphingosine-1 phosphate (S1P) which mediates several biological fu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::886190e757d0c8d81a940efd82b467a6
https://doi.org/10.3324/haematol.2017.167353

Effect of the BTK inhibitor ibrutinib on macrophage- and γδ T cell-mediated response against Mycobacterium tuberculosis

Autor: José Luis Marín Franco, Fernando Bezares, Enrique Podaza, Mercedes Borge, Céline Cougoule, María Belén Almejún, Luciana Balboa, Romina Gamberale, Denise Kviatcovsky, Isabelle Maridonneau-Parini, Melanie Genoula, Denise Risnik, Horacio Fernandez Grecco, María del Carmen Sasiain, Ana Colado, Federico Fuentes, María Cabrejo, Esteban Enrique Elías, Mirta Giordano, Carolina Jancic

Publikováno v: Blood Cancer Journal
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Blood Cancer Journal, Nature Publishing Group, 2018, 8 (11), ⟨10.1038/s41408-018-0136-x⟩
Blood Cancer Journal, Vol 8, Iss 11, Pp 1-6 (2018)

The Bruton’s tyrosine kinase (BTK) inhibitor ibrutinib is approved by the Food and Drug Administration for its use as first-line treatment in chronic lymphocytic leukemia (CLL). Despite its efficacy, patients treated with ibrutinib rarely achieve c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea0771ce6848524600d54f1eea6bd078
https://pubmed.ncbi.nlm.nih.gov/30397191