Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Mapaseka L. Seheri"'
Publikováno v:
Vaccines, Vol 12, Iss 3, p 273 (2024)
Bacterial lipopolysaccharides (LPSs) have been shown to promote enteric viral infections. This study tested the hypothesis that elevated levels of bacterial LPS improve oral rotavirus vaccine replication in South African infants. Stool samples were c
Externí odkaz:
https://doaj.org/article/3b7ee21dd6114efe9a1ccda2a1e6666b
Autor:
Robyn-Lee Potgieter, Peter N. Mwangi, Milton T. Mogotsi, Jeannine Uwimana, Leon Mutesa, Narcisse Muganga, Didier Murenzi, Lisine Tusiyenge, Mapaseka L. Seheri, A. Duncan Steele, Jason M. Mwenda, Martin M. Nyaga
Publikováno v:
Viruses, Vol 15, Iss 12, p 2321 (2023)
Although the introduction of rotavirus vaccines has substantially contributed to the reduction in rotavirus morbidity and mortality, concerns persist about the re-emergence of variant strains that might alter vaccine effectiveness in the long term. T
Externí odkaz:
https://doaj.org/article/dd966503499b4d3bb2da10be3bd8b22e
Autor:
Peter N. Mwangi, Robyn-Lee Potgieter, Jeannine Uwimana, Leon Mutesa, Narcisse Muganga, Didier Murenzi, Lisine Tusiyenge, Jason M. Mwenda, Milton T. Mogotsi, Kebareng Rakau, Mathew D. Esona, A. Duncan Steele, Mapaseka L. Seheri, Martin M. Nyaga
Publikováno v:
Pathogens, Vol 12, Iss 5, p 658 (2023)
Africa has a high level of genetic diversity of rotavirus strains, which is suggested to be a possible reason contributing to the suboptimal effectiveness of rotavirus vaccines in this region. One strain that contributes to this rotavirus diversity i
Externí odkaz:
https://doaj.org/article/092bb1ddf66948888b519336b715ae59
Autor:
Peter N. Mwangi, Robyn-Lee Potgieter, Julia Simwaka, Evans M. Mpabalwani, Jason M. Mwenda, Milton T. Mogotsi, Nonkululeko Magagula, Mathew D. Esona, A. Duncan Steele, Mapaseka L. Seheri, Martin M. Nyaga
Publikováno v:
Viruses, Vol 15, Iss 2, p 501 (2023)
The G2P[4] genotype is among the rotavirus strains that circulate commonly in humans. Several countries have reported its immediate upsurge after the introduction of rotavirus vaccination, raising concern about sub-optimal vaccine effectiveness again
Externí odkaz:
https://doaj.org/article/96579e4189d947bbb725374959353339
Autor:
Amy Strydom, Celeste M. Donato, Martin M. Nyaga, Simone S. Boene, Ina Peenze, Milton T. Mogotsi, Eva D. João, Benilde Munlela, A. Christiaan Potgieter, Mapaseka L. Seheri, Nilsa de Deus, Hester G. O’Neill
Publikováno v:
Pathogens, Vol 10, Iss 10, p 1308 (2021)
This study presents whole genomes of seven bovine rotavirus strains from South Africa and Mozambique. Double-stranded RNA, extracted from stool samples without prior adaptation to cell culture, was used to synthesise cDNA using a self-annealing ancho
Externí odkaz:
https://doaj.org/article/53aca513c189416fbf1f72bdd8654779
Autor:
Wairimu M. Maringa, Julia Simwaka, Peter N. Mwangi, Evans M. Mpabalwani, Jason M. Mwenda, M. Jeffrey Mphahlele, Mapaseka L. Seheri, Martin M. Nyaga
Publikováno v:
Viruses, Vol 13, Iss 9, p 1872 (2021)
Rotarix® vaccine was implemented nationwide in Zambia in 2013. In this study, four unusual strains collected in the post-vaccine period were subjected to whole genome sequencing and analysis. The four strains possessed atypical genotype constellatio
Externí odkaz:
https://doaj.org/article/6dbb587ada7a42108c115cad190a19a4
Autor:
Joshua Ndung’u Gikonyo, James Nyangao, Cecilia Mbae, Carlene Sang, Eliud Njagi, Joseph Ngeranwa, Mathew Esona, Mapaseka L. Seheri, Grace W. Gitau, Kedra Raini, Samuel Kariuki
Publikováno v:
BMC Research Notes, Vol 10, Iss 1, Pp 1-8 (2017)
Abstract Background Gastroenteritis is a public health concern due to high morbidity and mortality among children. Rotaviruses are the leading etiological agents of severe gastroenteritis in children and accounts for more than half a million deaths p
Externí odkaz:
https://doaj.org/article/206350ba4bf64b0aaac406f0322f8a89
Autor:
Sebotsana Rasebotsa, Jeannine Uwimana, Milton T. Mogotsi, Kebareng Rakau, Nonkululeko B. Magagula, Mapaseka L. Seheri, Jason M. Mwenda, M. Jeffrey Mphahlele, Saheed Sabiu, Richard Mihigo, Leon Mutesa, Martin M. Nyaga
Publikováno v:
Viruses, Vol 13, Iss 1, p 95 (2021)
Children in low-and middle-income countries, including Rwanda, experience a greater burden of rotavirus disease relative to developed countries. Evolutionary mechanisms leading to multiple reassortant rotavirus strains have been documented over time
Externí odkaz:
https://doaj.org/article/17d37cd11f4740beac6d751673eefa0f
Autor:
Milton T. Mogotsi, Peter N. Mwangi, Phillip A. Bester, M. Jeffrey Mphahlele, Mapaseka L. Seheri, Hester G. O’Neill, Martin M. Nyaga
Publikováno v:
Viruses, Vol 12, Iss 11, p 1260 (2020)
Establishing a diverse gut microbiota after birth is essential for preventing illnesses later in life. However, little knowledge exists about the total viral population (virome) present in the gut of infants during the early developmental stage, with
Externí odkaz:
https://doaj.org/article/6b2a5a50d3f44b0a89db2b6308caa932
Autor:
Peter N. Mwangi, Milton T. Mogotsi, Mapaseka L. Seheri, M. Jeffrey Mphahlele, Ina Peenze, Mathew D. Esona, Benjamin Kumwenda, A. Duncan Steele, Carl D. Kirkwood, Valantine N. Ndze, Francis E. Dennis, Khuzwayo C. Jere, Martin M. Nyaga
Publikováno v:
Vaccines, Vol 8, Iss 4, p 609 (2020)
Rotavirus G1P[8] strains account for more than half of the group A rotavirus (RVA) infections in children under five years of age, globally. A total of 103 stool samples previously characterized as G1P[8] and collected seven years before and seven ye
Externí odkaz:
https://doaj.org/article/5a95a395347a4c1fbf3e854140027f9a