Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Maozi Chen"'
Autor:
Yan Chen, Zhiwei Feng, Mingzhe Shen, Weiwei Lin, Yuanqiang Wang, Siyi Wang, Caifeng Li, Shengfeng Wang, Maozi Chen, Weiguang Shan, Xiang-Qun Xie
Publikováno v:
ACS Omega, Vol 5, Iss 5, Pp 2428-2439 (2020)
Externí odkaz:
https://doaj.org/article/78bee7c9bf1443ecb09a58bb5113f960
Publikováno v:
PLoS Genetics, Vol 8, Iss 3, p e1002602 (2012)
The calpains are physiologically important Ca(2+)-activated regulatory proteases, which are divided into typical or atypical sub-families based on constituent domains. Both sub-families are present in mammals, but our understanding of calpain functio
Externí odkaz:
https://doaj.org/article/891524b397894eafa61d5702d0333b2f
Publikováno v:
ACS Omega. 7:37476-37484
Transmissible and infectious viruses can cause large-scale epidemics around the world. This is because the virus can constantly mutate and produce different variants and subvariants to counter existing treatments. Therefore, a variety of treatments a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21aad2e3d5d0b4685422ede8b1f68e5
https://doi.org/10.1021/acsomega.2c04258
https://doi.org/10.1021/acsomega.2c04258
Publikováno v:
Crop Journal, Vol 12, Iss 5, Pp 1321-1332 (2024)
Plant calmodulins (CaMs) and calmodulin-like proteins (CMLs) mediate Ca2+ signaling in response to abiotic stresses. Manipulation of this signaling in crops could increase stress tolerance. We review methods for detecting Ca2+ signals, regulatory rol
Externí odkaz:
https://doaj.org/article/6d6c68e9011746bb93334ccfb5d45301
Autor:
Maozi Chen, Chih-Jung Chen, Hui Chen, Siyi Wang, Tianjian Liang, Jin Cheng, Zhiwei Feng, Xiang-Qun Xie
Publikováno v:
ACS Chemical Neuroscience. 12:1606-1620
Characterizing the structural basis of ligand recognition of adenosine A2A receptor (AA2AR) will facilitate its rational design and development of small molecules with high affinity and selectivity, as well as optimal therapeutic effects for pain, ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99005ff0fda05f0e0c7bacb4e7430eb4
https://doi.org/10.1021/acschemneuro.1c00082
https://doi.org/10.1021/acschemneuro.1c00082
Publikováno v:
ACS chemical neuroscience. 13(7)
Allosteric modulators (AMs) that bind allosteric sites can exhibit greater selectivity than the orthosteric ligands and can either enhance agonist-induced receptor activity (termed positive allosteric modulator or PAM), inhibit agonist-induced activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357e197c28f375456a189ed324f6c865
https://pubmed.ncbi.nlm.nih.gov/35298129
https://pubmed.ncbi.nlm.nih.gov/35298129
Publikováno v:
Briefings in Bioinformatics
Given the scale and rapid spread of the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there is an urgent need for medicines that can help before vaccines are available. In this study, we p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cfd568550d3ac7395542649f4843553
https://doi.org/10.1093/bib/bbaa155
https://doi.org/10.1093/bib/bbaa155
Autor:
Mingzhe Shen, Shengfeng Wang, Yuanqiang Wang, Weiwei Lin, Caifeng Li, Xiang-Qun Xie, Zhiwei Feng, Maozi Chen, Wei-Guang Shan, Yan Chen, Siyi Wang
Publikováno v:
ACS Omega, Vol 5, Iss 5, Pp 2428-2439 (2020)
Epilepsy is a common cause of serious cognitive disorders and is known to have impact on patients' memory and executive functions. Therefore, the development of antiepileptic drugs for the improvement of spatial learning and memory in patients with e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0eca070348571013cfcce10efd6153d
https://doi.org/10.1021/acsomega.9b03960
https://doi.org/10.1021/acsomega.9b03960
Autor:
Nan Wu, Maozi Chen, Jin Cheng, Siyi Wang, Xiang-Qun Xie, Yuanqiang Wang, Weiwei Lin, Zhiwei Feng
Publikováno v:
ACS Chemical Neuroscience. 10:3486-3499
The United States of America is fighting against one of its worst-ever drug crises. Over 900 people a week die from opioid- or heroin-related overdoses, while millions more suffer from opioid prescription addiction. Recently, drug overdoses caused by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f18cad49fc3c6b5416dea607e97645
https://doi.org/10.1021/acschemneuro.9b00109
https://doi.org/10.1021/acschemneuro.9b00109
Autor:
Jin, Cheng, Maozi, Chen, Siyi, Wang, Tianjian, Liang, Hui, Chen, Chih-Jung, Chen, Zhiwei, Feng, Xiang-Qun, Xie
Publikováno v:
ACS chemical neuroscience. 12(9)
Characterizing the structural basis of ligand recognition of adenosine A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::845924d4ea081877c3792c8a99c2cf21
https://pubmed.ncbi.nlm.nih.gov/33856784
https://pubmed.ncbi.nlm.nih.gov/33856784