Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Maozhou He"'
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/b45ffca8a5bc452db20b9a1b7d042e7b
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract O-GlcNAcylation is a conserved post-translational modification that attaches N-acetyl glucosamine (GlcNAc) to myriad cellular proteins. In response to nutritional and hormonal signals, O-GlcNAcylation regulates diverse cellular processes by
Externí odkaz:
https://doaj.org/article/491b1c93a42d4675ba8561d1486b2a0d
Publikováno v:
Frontiers in Earth Science, Vol 11 (2023)
The occurrence of over-excavation or under-excavation in tunnel construction poses significant safety risks. Moreover, there is currently no automatic estimation method available for real-time estimation of earthwork excavation, particularly in the c
Externí odkaz:
https://doaj.org/article/3390e7f95a354a69a739f41c9c66495d
Autor:
Tingting Li, Junyu Chen, Qingbing Zheng, Wenhui Xue, Limin Zhang, Rui Rong, Sibo Zhang, Qian Wang, Minqing Hong, Yuyun Zhang, Lingyan Cui, Maozhou He, Zhen Lu, Zhenyong Zhang, Xin Chi, Jinjin Li, Yang Huang, Hong Wang, Jixian Tang, Dong Ying, Lizhi Zhou, Yingbin Wang, Hai Yu, Jun Zhang, Ying Gu, Yixin Chen, Shaowei Li, Ningshao Xia
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Circulating subtypes of Influenza viruses seasonally change and therefore vaccines need to be matched to these strains each year, which is why there is a need for next-generation vaccines that can elicit broad and cross-type protection. Here, Li et a
Externí odkaz:
https://doaj.org/article/963fc991294c440fb4327bb6ee9a2182
Autor:
Guosong Wang, Zhenghui Zha, Pengfei Huang, Hui Sun, Yang Huang, Maozhou He, Tian Chen, Lina Lin, Zhenqin Chen, Zhibo Kong, Yuqiong Que, Tingting Li, Ying Gu, Hai Yu, Jun Zhang, Qingbing Zheng, Yixin Chen, Shaowei Li, Ningshao Xia
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Pseudorabies virus (PRV) is a major etiological agent of swine infectious diseases responsible for significant economic losses in the swine industry. The authors report the structures of the PRV A-capsid and C-capsid, shedding light on PRV’s assemb
Externí odkaz:
https://doaj.org/article/c1c0f7afda504519bbcbcb4b690ffa07
Autor:
Daning Wang, Xinlin Liu, Minxi Wei, Ciying Qian, Shuo Song, Jie Chen, Zhiping Wang, Qin Xu, Yurou Yang, Maozhou He, Xin Chi, Shiwen Huang, Tingting Li, Zhibo Kong, Qingbing Zheng, Hai Yu, Yingbin Wang, Qinjian Zhao, Jun Zhang, Ningshao Xia, Ying Gu, Shaowei Li
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
An effective vaccine for human papillomavirus (HPV) needs to protect from several genotypes. Here, Wang et al. provide a strategy to produce single capsomere-hybrid virus-like particle (chVLP) composed of capsomers of different genotypes and show tha
Externí odkaz:
https://doaj.org/article/a48ad75cb64149f78c08387b5f6a5505
Autor:
Xinlin Liu, Jie Chen, Zhiping Wang, Daning Wang, Maozhou He, Ciying Qian, Shuo Song, Xin Chi, Zhibo Kong, Qingbing Zheng, Yingbin Wang, Hai Yu, Qinjian Zhao, Jun Zhang, Shaowei Li, Ying Gu, Ningshao Xia
Publikováno v:
Emerging Microbes and Infections, Vol 8, Iss 1, Pp 1721-1733 (2019)
ABSTRACTHuman papillomavirus type 6 (HPV6) is the major etiologic agent of genital warts and recurrent respiratory papillomatosis. Although the commercial HPV vaccines cover HPV6, the neutralization sites and mode for HPV6 are poorly understood. Here
Externí odkaz:
https://doaj.org/article/127e331dfd4b48a9bc1feb13a471f194
Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity
Autor:
Zhihai Li, Shuo Song, Maozhou He, Daning Wang, Jingjie Shi, Xinlin Liu, Yunbing Li, Xin Chi, Shuangping Wei, Yurou Yang, Zhiping Wang, Jinjin Li, Huilian Qian, Hai Yu, Qingbing Zheng, Xiaodong Yan, Qinjian Zhao, Jun Zhang, Ying Gu, Shaowei Li, Ningshao Xia
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
More than 18 human papillomaviruses (HPV) are associated with cervical cancer, and ideally vaccines should protect from all of them. Here, the authors engineer a triple-type, chimeric HPV vaccine, using loop swapping, that elicits robust neutralizing
Externí odkaz:
https://doaj.org/article/3de48f3d69ed4d74b8bb0b144ffafdc8
Autor:
Minxi Wei, Daning Wang, Zhihai Li, Shuo Song, Xianglin Kong, Xiaobing Mo, Yurou Yang, Maozhou He, Zhongyi Li, Bo Huang, Zhijie Lin, Huirong Pan, Qingbing Zheng, Hai Yu, Ying Gu, Jun Zhang, Shaowei Li, Ningshao Xia
Publikováno v:
Emerging Microbes and Infections, Vol 7, Iss 1, Pp 1-12 (2018)
Highlights • N-terminal truncations promote the soluble expression of HPV L1 proteins in E. coli and their self-assembly of T = 7 icosahedral particle in vitro • An HPV 9-valent vaccine candidate was formulated with E. coli-derived HPV 6, 11, 16,
Externí odkaz:
https://doaj.org/article/b6b67d340a8a46ba8106b45bc5019f4f
Autor:
Longfa Xu, Qingbing Zheng, Shaowei Li, Maozhou He, Yangtao Wu, Yongchao Li, Rui Zhu, Hai Yu, Qiyang Hong, Jie Jiang, Zizhen Li, Shuxuan Li, Huan Zhao, Lisheng Yang, Wangheng Hou, Wei Wang, Xiangzhong Ye, Jun Zhang, Timothy S. Baker, Tong Cheng, Z. Hong Zhou, Xiaodong Yan, Ningshao Xia
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Coxsackievirus A6 (CVA6) causes hand, foot and mouth disease in children. Here the authors present the CVA6 procapsid and A-particle cryo-EM structures and identify an immune-dominant neutralizing epitope, which can be exploited for vaccine developme
Externí odkaz:
https://doaj.org/article/f06de03619794e4cae31c9264a758c1f