Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Maozhen Qi"'
Autor:
Maozhen Qi, Qingran Jiang, Siwei Yang, Chenxi Zhang, Jianguo Liu, Wei Liu, Pengfei Lin, Huatao Chen, Dong Zhou, Keqiong Tang, Aihua Wang, Yaping Jin
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 122-136 (2022)
Trueperella pyogenes is an important bacterial pathogen of a wide range of domestic and wild animals. Autophagy plays a key role in eliminating T. pyogenes in a process that is dependent on mechanistic target of rapamycin (mTOR). The endoplasmic reti
Externí odkaz:
https://doaj.org/article/df6d48b3736f4910b23e0f8c7522bab2
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract Several brain neuronal populations transmit both the excitatory and inhibitory neurotransmitters, glutamate, and GABA. However, it remains largely unknown whether these opposing neurotransmitters are co-released simultaneously or are indepen
Externí odkaz:
https://doaj.org/article/14b2115d10904775b76838f068f502b3
Autor:
Maozhen Qi, Qingran Jiang, Siwei Yang, Chenxi Zhang, Jianguo Liu, Wei Liu, Pengfei Lin, Huatao Chen, Dong Zhou, Keqiong Tang, Aihua Wang, Yaping Jin
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 122-136 (2022)
Trueperella pyogenes is an important bacterial pathogen of a wide range of domestic and wild animals. Autophagy plays a key role in eliminating T. pyogenes in a process that is dependent on mechanistic target of rapamycin (mTOR). The endoplasmic reti
Autor:
Maozhen Qi, Jianguo Liu, Huatao Chen, Aihua Wang, Pengfei Lin, Hongyu Niu, Xinyu Wang, Dong Zhou, Qingran Jiang, Yaping Jin
Publikováno v:
Braz J Microbiol
Trueperella pyogenes (T. pyogenes) is a common opportunistic pathogen of many livestock and play an important regulation role during multibacterial infection and interaction with the host by its primary virulence factor pyolysin (PLO). The purpose of
Publikováno v:
eLife, Vol 13 (2024)
Protein kinase A (PKA) plays essential roles in diverse cellular functions. However, the spatiotemporal dynamics of endogenous PKA upon activation remain debated. The classical model predicts that PKA catalytic subunits dissociate from regulatory sub
Externí odkaz:
https://doaj.org/article/7a1ecb86412c48babe8dd9a9434eaacf
Autor:
Aya Matsui, Cathy Spangler, Johannes Elferich, Momoko Shiozaki, Nikki Jean, Xiaowei Zhao, Maozhen Qin, Haining Zhong, Zhiheng Yu, Eric Gouaux
Publikováno v:
eLife, Vol 13 (2024)
Chemical synapses are the major sites of communication between neurons in the nervous system and mediate either excitatory or inhibitory signaling. At excitatory synapses, glutamate is the primary neurotransmitter and upon release from presynaptic ve
Externí odkaz:
https://doaj.org/article/f0adfa4b2dca4bd1a9d62ccac9d9b6db
Autor:
Yaping Jin, Huatao Chen, Wei Liu, Maozhen Qi, Keqiong Tang, Fu-Rong Bai, Dong Zhou, Feijie Zhi, Aihua Wang, Huan Liu, Guangdong Zhang, Junmei Li, Pengfei Lin
Publikováno v:
Oncotarget
Brucella is an intracellular bacterium that causes the zoonosis brucellosis worldwide. Alveolar macrophages (AM) constitute the main cell target of inhaled Brucella. Brucella thwarts immune surveillance and evokes endoplasmic reticulum (ER) stress to
Publikováno v:
The Journal of Biological Chemistry
Birt-Hogg-Dubé (BHD) syndrome is a multiorgan disorder caused by inactivation of the folliculin (FLCN) protein. Previously, we identified FLCN as a binding protein of Rab11A, a key regulator of the endocytic recycling pathway. This finding implies t
Autor:
Haining Zhong, Cesar C Ceballos, Crystian I Massengill, Michael A Muniak, Lei Ma, Maozhen Qin, Stefanie Kaech Petrie, Tianyi Mao
Publikováno v:
eLife, Vol 10 (2021)
Precise and efficient insertion of large DNA fragments into somatic cells using gene editing technologies to label or modify endogenous proteins remains challenging. Non-specific insertions/deletions (INDELs) resulting from the non-homologous end joi
Externí odkaz:
https://doaj.org/article/8ae934b12a2342f6aefbc97b9fbe8fff
Autor:
Shane E. Tillo, Wei-Hong Xiong, Maho Takahashi, Sheng Miao, Adriana L. Andrade, Dale A. Fortin, Guang Yang, Maozhen Qin, Barbara F. Smoody, Philip J.S. Stork, Haining Zhong
Publikováno v:
Cell Reports, Vol 19, Iss 3, Pp 617-629 (2017)
Summary: Protein kinase A (PKA) has diverse functions in neurons. At rest, the subcellular localization of PKA is controlled by A-kinase anchoring proteins (AKAPs). However, the dynamics of PKA upon activation remain poorly understood. Here, we repor
Externí odkaz:
https://doaj.org/article/a540d9f1d44143628be3f576edba3b25