Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Maoyun, Sun"'
Autor:
Ronald Allan M. Panganiban, Zhiping Yang, Maoyun Sun, Chan Young Park, David I. Kasahara, Niccole Schaible, Ramaswamy Krishnan, Alvin T. Kho, Elliot Israel, Marc B. Hershenson, Scott T. Weiss, Blanca E. Himes, Jeffrey J. Fredberg, Kelan G. Tantisira, Stephanie A. Shore, Quan Lu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
The underlying mechanisms of how obesity increases asthma prevalence and severity are not well understood. Here, the authors show that antagonizing cholecystokinin and its receptor, CCKAR, in the lung attenuates obesity-associated airway hyperrespons
Externí odkaz:
https://doaj.org/article/627590137e8e4854b2f7c749238e36dd
Autor:
Mengyuan Kan, Maoyun Sun, Xiaofeng Jiang, Avantika R. Diwadkar, Vishal Parikh, Gaoyuan Cao, Eric Gebski, William Jester, Bo Lan, Reynold A. Panettieri, Cynthia Koziol-White, Quan Lu, Blanca E. Himes
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract Background CCAAT/Enhancer Binding Protein D (CEBPD), a pleiotropic glucocorticoid-responsive transcription factor, modulates inflammatory responses. Of relevance to asthma, expression of CEBPD in airway smooth muscle (ASM) increases with glu
Externí odkaz:
https://doaj.org/article/a5ddadf8bc3f433fb4bed68c1ebc7034
Autor:
Maoyun Sun, Alvin T. Kho, Kelan G. Tantisira, Scott T. Weiss, Anshul Tiwari, Quan Lu, Jiang Li, Michael J. McGeachie
Publikováno v:
The Journal of allergy and clinical immunology
Background: Many microRNAs (miRNAs) have been associated with asthma and chronic obstructive pulmonary disease (COPD). Longitudinal lung function growth trajectories of children with asthma—normal growth, reduced growth (RG), early decline (ED), an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cca123c0c559d8b247adb487d294bd7a
https://doi.org/10.1016/j.jaci.2020.11.048
https://doi.org/10.1016/j.jaci.2020.11.048
Autor:
Joshua S Davis, Maoyun Sun, Alvin T Kho, Kip G Moore, Jody M Sylvia, Scott T Weiss, Quan Lu, Kelan G Tantisira
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180329 (2017)
Circulating microRNAs (miRNA) are promising biomarkers for human diseases. Our study hypothesizes that circulating miRNA would reveal candidate biomarkers related to airway hyperresponsiveness (AHR) and provide biologic insights into asthma epigeneti
Externí odkaz:
https://doaj.org/article/b73534e2a9bc417aa51832aa6eacc187
Autor:
Jeffrey J. Fredberg, Blanca E. Himes, Ronald Pangniban, Alvin Koh, Maoyun Sun, Elliot Israel, Quan Lu, David I. Kasahara, Marc Hershenson, Stephanie A. Shore, Scott T. Weiss, Kelan G. Tantisira, Chan Young Park
Obesity is a significant co-morbidity that associates with increased prevalence and severity of asthma. The mechanism underlying the obesity-asthma association remains poorly understood, and for obese asthmatics there is no effective therapy for obes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::147fd35e0ccaf9dbb931359fe9ed572a
https://doi.org/10.21203/rs.3.rs-841619/v1
https://doi.org/10.21203/rs.3.rs-841619/v1
Autor:
Ronald Allan M, Panganiban, Zhiping, Yang, Maoyun, Sun, Chan Young, Park, David I, Kasahara, Niccole, Schaible, Ramaswamy, Krishnan, Alvin T, Kho, Elliot, Israel, Marc B, Hershenson, Scott T, Weiss, Blanca E, Himes, Jeffrey J, Fredberg, Kelan G, Tantisira, Stephanie A, Shore, Quan, Lu
Publikováno v:
Nature communications. 14(1)
Obesity increases asthma prevalence and severity. However, the underlying mechanisms are poorly understood, and consequently, therapeutic options for asthma patients with obesity remain limited. Here we report that cholecystokinin-a metabolic hormone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::716f984ceea845e45c2a23e6bec029a6
https://pubmed.ncbi.nlm.nih.gov/36599824
https://pubmed.ncbi.nlm.nih.gov/36599824
Autor:
Maoyun Sun, Blanca E. Himes, Maya Shumyatcher, Quan Lu, Ronald Allan M Panganiban, Hae-Ryung Park
Publikováno v:
Proceedings of the National Academy of Sciences. 116:13384-13393
Sensing misfolded proteins in the endoplasmic reticulum (ER), cells initiate the ER stress response and, when overwhelmed, undergo apoptosis. However, little is known about how cells prevent excessive ER stress response and cell death to restore home
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2cf410ab2a9a3659d67804f317a9995
https://doi.org/10.1073/pnas.1906275116
https://doi.org/10.1073/pnas.1906275116
Publikováno v:
A30. CONTRACT AND RELAX: WHAT'S NEW IN AIRWAY SMOOTH MUSCLE MECHANISMS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef2c959c1800cf73c5cf3a74461f4798
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1260
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1260
Autor:
Carlos Iribarren, Ann Chen Wu, Maoyun Sun, Ronald Allan M Panganiban, Scott H. Randell, Jin-Ah Park, Blanca E. Himes, Hae-Ryung Park, Jennifer A. Mitchel, Amber Dahlin, Stephanie A. Shore, Elliot Israel, Mengyuan Kan, Quan Lu, Kelan G. Tantisira, Scott T. Weiss, Eric Jorgenson
Background Genetic variants in the chromosomal region 17q21 are consistently associated with asthma. However, mechanistic studies have not yet linked any of the associated variants to a function that could influence asthma, and as a result, the ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4257838421a555c875b940f5c8d8c755
https://europepmc.org/articles/PMC6037620/
https://europepmc.org/articles/PMC6037620/
Autor:
Alvin T. Kho, Maoyun Sun, Kip G. Moore, Jody M. Sylvia, Quan Lu, Scott T. Weiss, Kelan G. Tantisira, Joshua S. Davis
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 7, p e0180329 (2017)
PLoS ONE, Vol 12, Iss 7, p e0180329 (2017)
Introduction Circulating microRNAs (miRNA) are promising biomarkers for human diseases. Our study hypothesizes that circulating miRNA would reveal candidate biomarkers related to airway hyperresponsiveness (AHR) and provide biologic insights into ast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e9f93f7bfb71adc16d868e6a6da26c8
http://europepmc.org/articles/PMC5531511
http://europepmc.org/articles/PMC5531511