Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Maoxue Tang"'
Publikováno v:
Frontiers in Dental Medicine, Vol 2 (2021)
Preventing the spread of Coronavirus Disease 2019 (COVID-19) has become the focus of epidemiologists as the highly infectious respiratory disease spreads primarily by close, person-to-person contact via droplets or the skin. Aerosol dissemination may
Externí odkaz:
https://doaj.org/article/361cfa07fabc4e8aa9da1142d083d69e
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 9, Pp 1923-1932 (2019)
Abstract Proper development and function of the mammalian brain is critically dependent on a steady supply of its chief energy source, glucose. Such supply is mediated by the glucose transporter 1 (Glut1) protein. Paucity of the protein stemming from
Externí odkaz:
https://doaj.org/article/4dfaa03aed68435fbe6e79770e081191
Autor:
Maoxue Tang, Umrao R Monani
Publikováno v:
Neuroscience Insights, Vol 16 (2021)
Considering its small size relative to the rest of the body, the mammalian brain has a disproportionately high energy requirement. This energy is supplied to the brain mainly in the form of glucose through the principal cerebral glucose transporter,
Externí odkaz:
https://doaj.org/article/f9b4a4910761432bbdf412832cb3ecaf
Autor:
Maoxue Tang, Sarah H. Park, Sabrina Petri, Hang Yu, Carlos B. Rueda, E. Dale Abel, Carla Y. Kim, Elizabeth M.C. Hillman, Fanghua Li, Yeojin Lee, Lei Ding, Smitha Jagadish, Wayne N. Frankel, Darryl C. De Vivo, Umrao R. Monani
Publikováno v:
JCI Insight, Vol 6, Iss 3 (2021)
Paucity of the glucose transporter-1 (Glut1) protein resulting from haploinsufficiency of the SLC2A1 gene arrests cerebral angiogenesis and disrupts brain function to cause Glut1 deficiency syndrome (Glut1 DS). Restoring Glut1 to Glut1 DS model mice
Externí odkaz:
https://doaj.org/article/1207bc382e6a434aa49d1260aea515b1
Autor:
Maoxue Tang, Guangping Gao, Carlos B. Rueda, Hang Yu, David N. Thibodeaux, Tomoyuki Awano, Kristin M. Engelstad, Maria-Jose Sanchez-Quintero, Hong Yang, Fanghua Li, Huapeng Li, Qin Su, Kara E. Shetler, Lynne Jones, Ryan Seo, Jonathan McConathy, Elizabeth M. Hillman, Jeffrey L. Noebels, Darryl C. De Vivo, Umrao R. Monani
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Glut1-deficiency syndrome is a severe neurodevelopmental disorder characterized by low brain glucose and epileptic seizures. Tanget al. show that in model mice, low Glut1 leads to defects of the brain vasculature, and that AAV9-based gene therapy at
Externí odkaz:
https://doaj.org/article/cfe083483d664856ac5c4ced1381ccce
Autor:
Qingqing Wang, Lili Qian, Shengwang Jiang, Chunbo Cai, Dezun Ma, Pengfei Gao, Hegang Li, Ke Jiang, Maoxue Tang, Jian Hou, Jie Liu, Wentao Cui
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150937 (2016)
The neo (neomycin phosphotransferase) gene is widely used as a selection marker in the production of genetically engineered animals and plants. Recent attention has been focused on safety concerns regarding neo transgene expression. In this study, ne
Externí odkaz:
https://doaj.org/article/d8186b5db89e4b20be43f1a81eb006a8
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 9, Pp 1923-1932 (2019)
Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology
Proper development and function of the mammalian brain is critically dependent on a steady supply of its chief energy source, glucose. Such supply is mediated by the glucose transporter 1 (Glut1) protein. Paucity of the protein stemming from mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1315d7a1a6aba28ceed366219139284
https://doaj.org/article/4dfaa03aed68435fbe6e79770e081191
https://doaj.org/article/4dfaa03aed68435fbe6e79770e081191
Autor:
Umrao R. Monani, Maoxue Tang
Publikováno v:
Neuroscience Insights, Vol 16 (2021)
Neuroscience Insights
Neuroscience Insights
Considering its small size relative to the rest of the body, the mammalian brain has a disproportionately high energy requirement. This energy is supplied to the brain mainly in the form of glucose through the principal cerebral glucose transporter,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aede7a0d245dd5a714f05e6c3118193c
https://doaj.org/article/f9b4a4910761432bbdf412832cb3ecaf
https://doaj.org/article/f9b4a4910761432bbdf412832cb3ecaf
Autor:
Sarah H. Park, Hang Yu, Smitha Jagadish, Lei Ding, Wayne N. Frankel, Umrao R. Monani, Yeojin Lee, Maoxue Tang, Carla Kim, Sabrina Petri, Carlos B. Rueda, Fanghua Li, Elizabeth M. C. Hillman, E. Dale Abel, Darryl C. De Vivo
Publikováno v:
JCI Insight, Vol 6, Iss 3 (2021)
JCI Insight
JCI Insight
Paucity of the glucose transporter-1 (Glut1) protein resulting from haploinsufficiency of the SLC2A1 gene arrests cerebral angiogenesis and disrupts brain function to cause Glut1 deficiency syndrome (Glut1 DS). Restoring Glut1 to Glut1 DS model mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c701f7fb2f58a8ac0a221c48aa6e554
https://doaj.org/article/1207bc382e6a434aa49d1260aea515b1
https://doaj.org/article/1207bc382e6a434aa49d1260aea515b1
Autor:
Jonathan McConathy, Guangping Gao, Lynne Jones, Hang Yu, David N. Thibodeaux, Umrao R. Monani, Huapeng Li, Fanghua Li, Darryl C. De Vivo, Kara E. Shetler, Maoxue Tang, Elizabeth M. C. Hillman, Hong Yang, Maria-Jose Sanchez-Quintero, Kristin Engelstad, Carlos B. Rueda, Jeffrey L. Noebels, Tomoyuki Awano, Qin Su, Ryan Seo
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications
Nature Communications
Haploinsufficiency of the SLC2A1 gene and paucity of its translated product, the glucose transporter-1 (Glut1) protein, disrupt brain function and cause the neurodevelopmental disorder, Glut1 deficiency syndrome (Glut1 DS). There is little to suggest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ee27de18506e0150279d2416310ddc
https://doaj.org/article/cfe083483d664856ac5c4ced1381ccce
https://doaj.org/article/cfe083483d664856ac5c4ced1381ccce