Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Maoxu Ge"'
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 4, Pp 679-688 (2020)
Background & Aims: Inflammation plays an important role in the pathogenesis of cholestatic liver injury, but it is unclear whether the inflammasome is involved and is the objective of this study. Methods: Gene expression was analyzed in the livers of
Externí odkaz:
https://doaj.org/article/bce0d41b529c4e1899fe227a11251bd0
Publikováno v:
Molecules, Vol 25, Iss 4, p 773 (2020)
Twenty 9O-substituted palmatine derivatives were prepared and tested for their biological effect against collagen α1 (I) (COL1A1) promotor in human hepatic stellate LX-2 cells. The structure−activity relationship (SAR) indicated that the introduct
Externí odkaz:
https://doaj.org/article/ffd817eb7f704af29d7fabef2fcd93b6
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 4, Pp 679-688 (2020)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Inflammation plays an important role in the pathogenesis of cholestatic liver injury, but it is unclear whether the inflammasome is involved and is the objective of this study. Methods Gene expression was analyzed in the livers of p
Autor:
Qian Zhang, Yuzhuo Wu, Maoxu Ge, Guiyang Xia, Huan Xia, Lingyan Wang, Xiaohong Wei, Hongwei He, Sheng Lin
Publikováno v:
Journal of Ethnopharmacology. 299:115678
Hepatic fibrosis is a major consequence of liver disease. Radix Paeoniae Rubra (RPR), the dry root of Paeonia lactiflora Pall., has a long history of clinical application in traditional Chinese medicine (TCM) for the treatment of liver diseases. The
Autor:
Rong-Guang Shao, Dong-ke Yu, Maoxu Ge, Hong-Tao Liu, Juxian Wang, Wei-xiao Niu, Yi-xuan Zhang, Hongwei He, Shi-Ying Cai, Zhang Na, Ren Jinfeng, Yucheng Wang
Publikováno v:
Acta Pharmacol Sin
The manipulation of bile acid (BA) homeostasis by blocking the ileal apical Na(+)-dependent bile salt transporter (ASBT/SLC10A2) may have therapeutic effects in nonalcoholic fatty liver disease. We developed a novel ASBT inhibitor, an N-(3,4-o-dichlo
Publikováno v:
Molecules, Vol 25, Iss 4, p 773 (2020)
Molecules
Volume 25
Issue 4
Molecules
Volume 25
Issue 4
Twenty 9O-substituted palmatine derivatives were prepared and tested for their biological effect against collagen &alpha
1 (I) (COL1A1) promotor in human hepatic stellate LX-2 cells. The structure&minus
activity relationship (SAR) indicated
1 (I) (COL1A1) promotor in human hepatic stellate LX-2 cells. The structure&minus
activity relationship (SAR) indicated
Autor:
Jianzhong Yu, Shuangshuang Zhao, Wuli Zhao, Hong Liu, Maoxu Ge, Yi-xuan Zhang, Hongwei He, Yongzhan Zhen, Rong-Guang Shao, Naren Li
Publikováno v:
British Journal of Pharmacology. 174:1147-1160
Background and purpose Dihydrotanshinone I (DHI), a lipophilic component of traditional Chinese medicine Salvia miltiorrhiza Bunge, has various therapeutic effects. We investigated the anti-fibrotic effect of DHI and its underlying mechanisms in vitr
Publikováno v:
Journal of Asian Natural Products Research. 19:109-113
Hepatic fibrosis is a wound-healing response to chronic liver injury caused by various pathogenesis, such as hepatitis virus infection, drugs toxicity and autoimmune imbalances. Autophagy, a cellular process degrading damaged organelles or aggregativ