Zobrazeno 1 - 10
of 466
pro vyhledávání: '"Maosheng Cheng"'
Autor:
Ting Wang, Yueting Hua, Fangbo Deng, Rui Wen, Haoyu Zhang, Chunshi Li, Yang Liu, Maosheng Cheng
Publikováno v:
ACS Omega, Vol 9, Iss 36, Pp 37942-37952 (2024)
Externí odkaz:
https://doaj.org/article/88db5cb5b52c44948ddeb32572254eb9
Autor:
Caihua Zhang, Kang Li, Hongzhang Zhu, Maosheng Cheng, Shuang Chen, Rongsong Ling, Cheng Wang, Demeng Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Enoblituzumab, an immunotherapeutic agent targeting CD276, shows both safety and efficacy in activating T cells and oligodendrocyte-like cells against various cancers. Preclinical studies and mouse models suggest that therapies targeting CD2
Externí odkaz:
https://doaj.org/article/71a9fb36e0b74d7cb0b7f081fcbc759c
Autor:
Kang Li, Caihua Zhang, Ruoxing Zhou, Maosheng Cheng, Rongsong Ling, Gan Xiong, Jieyi Ma, Yan Zhu, Shuang Chen, Jie Chen, Demeng Chen, Liang Peng
Publikováno v:
International Journal of Oral Science, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Head and neck squamous cell carcinoma (HNSCC) is characterized by high recurrence or distant metastases rate and the prognosis is challenging. There is mounting evidence that tumor-infiltrating B cells (TIL-Bs) have a crucial, synergistic ro
Externí odkaz:
https://doaj.org/article/3f8a618e16bb4082914f548d21a399c4
Autor:
Maosheng Cheng, Shuang Chen, Kang Li, Ganping Wang, Gan Xiong, Rongsong Ling, Caihua Zhang, Zhihui Zhang, Hui Han, Zhi Chen, Xiaochen Wang, Yu Liang, Guoli Tian, Ruoxing Zhou, Yan Zhu, Jieyi Ma, Jiahong Liu, Shuibin Lin, Hao Xu, Demeng Chen, Yang Li, Liang Peng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Interplay between innate and adaptive immune cells is important for the antitumor immune response. However, the tumor microenvironment may turn immune suppressive, and tumor associated macrophages are playing a role in this transition. Here,
Externí odkaz:
https://doaj.org/article/73b9a51ecf3d46e89fc737e515933959
Autor:
Renming Fan, Ruizhuo Lin, Shuo Zhang, Aohua Deng, Yongrui Hai, Junyan Zhuang, Yang Liu, Maosheng Cheng, Gaofei Wei
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 4, Pp 1742-1758 (2024)
Mitochondrial membrane remodeling can trigger the release of mitochondrial DNA (mtDNA), leading to the activation of cellular oxidative stress and immune responses. While the role of mitochondrial membrane remodeling in promoting inflammation in hepa
Externí odkaz:
https://doaj.org/article/2246674c496b4cbdaf7c70db58d65f07
Autor:
Yu Liang, Shuang Chen, Zhi Chen, Fang Peng, Qianwen Liu, Gan Xiong, Caihua Zhang, Maosheng Cheng, Rongsong Ling, Demeng Chen, Qimin Zhou
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 5 (2024)
Background CD276 (B7-H3), a pivotal immune checkpoint, facilitates tumorigenicity, invasiveness, and metastasis by escaping immune surveillance in a variety of tumors; however, the underlying mechanisms facilitating immune escape in esophageal squamo
Externí odkaz:
https://doaj.org/article/7785bacbd26142a7b739cff8f9780d15
Autor:
Hui Han, Yucong Sun, Wei Wei, Zixin Huang, Maosheng Cheng, Hongshen Qiu, Juan Wang, Siyi Zheng, Lianlian Liu, Qiang Zhang, Canfeng Zhang, Jieyi Ma, Siyao Guo, Zhaoyu Wang, Zhenpeng Li, Xu Jiang, Shuibin Lin, Qianwen Liu, Shuishen Zhang
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109327- (2024)
Summary: Emerging studies have demonstrated the link between RNA modifications and various cancers, while the predictive value and functional mechanisms of RNA modification-related genes (RMGs) in esophageal squamous cell carcinoma (ESCC) remain uncl
Externí odkaz:
https://doaj.org/article/d26ae0dca59d488eb95f86eb65e7e171
Publikováno v:
ACS Omega, Vol 8, Iss 44, Pp 41876-41884 (2023)
Externí odkaz:
https://doaj.org/article/385818f7eb264717883834f2f64c4f6f
Publikováno v:
Drug Delivery, Vol 30, Iss 1 (2023)
AbstractAiming to address the insufficient endocytosis ability of traditional albumin drug conjugates, this paper reports elegant guanidine modification to improve efficacy for the first time. A series of modified albumin drug conjugates were designe
Externí odkaz:
https://doaj.org/article/0349dbb13e0a4bb4bd9747964596d3b2
Autor:
Huali Yang, Hongwei Jia, Minghui Deng, Kaicheng Zhang, Yaoyang Liu, Yang Liu, Maosheng Cheng, Wei Xiao
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
A series of OA-tacrine hybrids with the alkylamine linker was designed, synthesized, and evaluated as effective cholinesterase inhibitors for the treatment of Alzheimer’s disease (AD). Biological activity results demonstrated that some hybrids poss
Externí odkaz:
https://doaj.org/article/3a3d67535a944d23a806dd223892a50f