Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Maolu Yin"'
Autor:
Maolu Yin, Manizheh Izadi, Karin Tenglin, Thibault Viennet, Liting Zhai, Ge Zheng, Haribabu Arthanari, Laura M. K. Dassama, Stuart H. Orkin
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Transcription factors (TFs) control numerous genes that are directly relevant to many human disorders. However, developing specific reagents targeting TFs within intact cells is challenging due to the presence of highly disordered regions within thes
Publikováno v:
Molecular cell. 73(3)
Summary CRISPR-Cas (clustered regularly interspaced short palindromic repeats-CRISPR-associated proteins) systems provide prokaryotic cells with adaptive immunity against invading bacteriophages. Bacteriophages counteract bacterial responses by encod
Publikováno v:
Cell research. 27(11)
CTCF, a conserved 3D genome architecture protein, determines proper genome-wide chromatin looping interactions through directional binding to specific sequence elements of four modules within numerous CTCF-binding sites (CBSs) by its 11 zinc fingers
Publikováno v:
Molecular cell. 65(2)
C2c1 is a type V-B CRISPR-Cas system dual-RNA-guided DNA endonuclease. Here, we report the crystal structure of Alicyclobacillus acidoterrestris C2c1 in complex with a chimeric single-molecule guide RNA (sgRNA). AacC2c1 exhibits a bi-lobed architectu
Publikováno v:
Journal of the Science of Food and Agriculture. 93:375-381
BACKGROUND:Pectinmethylesterase(PME)catalysesthehydrolysisofthemethylesterofpectin,yieldingfreecarboxylgroups and methanol. PME is widely used in the food, cosmetic and pharmaceutical industries. RESULTS: PME from Aspergillus niger was constitutively
Publikováno v:
Journal of the science of food and agriculture. 93(2)
Pectin methylesterase (PME) catalyses the hydrolysis of the methyl ester of pectin, yielding free carboxyl groups and methanol. PME is widely used in the food, cosmetic and pharmaceutical industries.PME from Aspergillus niger was constitutively expre
Publikováno v:
Cell. (4):840-853
SummaryBacteria acquire memory of viral invaders by incorporating invasive DNA sequence elements into the host CRISPR locus, generating a new spacer within the CRISPR array. We report on the structures of Cas1-Cas2-dual-forked DNA complexes in an eff