Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Maokai Gong"'
Publikováno v:
Metabolism. 59:1372-1378
We previously showed that quercetin expresses its antiatherogenic effects by up-regulating paraoxonase 1 (PON1) gene and high-density lipoprotein's protective capacity against low-density lipoprotein oxidation. In an attempt to elucidate the mechanis
Autor:
Ravi Varatharajalu, Mamatha Garige, Christopher F. Spurney, Maokai Gong, Takako Nagata, Leslie C. Leckey, Raj Lakshman
Publikováno v:
Alcoholism: Clinical and Experimental Research. 34:1535-1542
Background: As moderate wine drinking is atheroprotective, it is clinically relevant to elucidate its possible mechanism/s of action/s. Our objective is to demonstrate the potential benefits of the wine components, quercetin and ethanol, on the devel
Autor:
Maokai Gong, Chandra Gottipatti, Ravi Varatharajalu, Mamatha Garige, Raj Lakshman, Leslie C. Leckey, Philippe Marmillot
Publikováno v:
Biochemical and Biophysical Research Communications. 379:1001-1004
Paraoxonase 1 (PON1) protects the oxidative modification of low-density lipoprotein (LDL) and is a major anti-atherosclerotic protein component of high-density lipoprotein (HDL). Quercetin, a ubiquitous plant flavonoid, has been shown to have a numbe
Autor:
Doris B. Strader, Leonard B. Seeff, Maokai Gong, Philippe Marmillot, M. Raj Lakshman, Manjunath N. Rao, David A Palmer
Publikováno v:
Metabolism. 52:1287-1294
Paraoxonase 1 (PON) may contribute to the cardioprotective action of high-density lipoprotein (HDL) because it inhibits low-density lipoprotein (LDL) oxidation, a prerequisite for the onset of atherosclerosis. Because light drinking and heavy drinkin
Publikováno v:
Gene. 233:21-31
Decreased reduced folate carrier (RFC) activity has been associated with MTX resistance in experimental models of transport-mediated MTX resistance, and has been attributed to changes in the expression of RFC1, the gene that encodes a protein with th
Autor:
Kenneth H. Cowan, S. Percy Ivy, Jeffrey A. Moscow, Tatiana Connolly, Maokai Gong, James Yess, Takao Ohnuma
Publikováno v:
Blood. 89:2494-2499
Ohnuma et al reported a series of methotrexate-resistant MOLT-3 human T-cell acute lymphoblastic leukemia cell lines that showed decreasing methotrexate (MTX) uptake as the sublines acquired increasing MTX resistance (Cancer Res 45:1815, 1985). The a
Autor:
Leslie C, Leckey, Mamatha, Garige, Ravi, Varatharajalu, Maokai, Gong, Takako, Nagata, Christopher F, Spurney, Raj M, Lakshman
Publikováno v:
Alcoholism, clinical and experimental research. 34(9)
As moderate wine drinking is atheroprotective, it is clinically relevant to elucidate its possible mechanism/s of action/s. Our objective is to demonstrate the potential benefits of the wine components, quercetin and ethanol, on the development of ao
Publikováno v:
Alcoholism, clinical and experimental research. 34(3)
BACKGROUND Paraoxonase (PON1) is an antioxidant enzyme that prevents LDL oxidation as well as detoxifies homocysteine thiolactone (HCTL), both of which can cause atherosclerosis. Chronic alcohol (ETOH) and high omega-3 polyunsaturated fatty acids (om
Autor:
Maokai Gong, Mamatha Garige, Leslie C. Leckey, Ravi Varatharajalu, Raj Lakshman, Samir Zakhari
Publikováno v:
Genesnutrition. 5(2)
While the effects of chronic ethanol consumption on liver have been well studied and documented, its effect on the cardiovascular system is bimodal. Thus, moderate drinking in many population studies is related to lower prevalence of coronary artery
Autor:
Robert S. Redman, Magnus A. Azuine, Mamatha Garige, Kenneth Hirsch, Maokai Gong, Devanshi Seth, M. Raj Lakshman, Richard Amdur, Leslie Castillo, Paul S. Haber
Publikováno v:
Metabolism: clinical and experimental. 57(12)
Hepatic steatosis and steatohepatitis are frequent results of long-term ethanol exposure. We have previously demonstrated that long-term ethanol down-regulates Galbetal, 4GlcNAc alpha2, 6-sialyltransferase (ST6Gal1), leading to defective glycosylatio