Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Maohua Pei"'
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-17 (2021)
Abstract Pyroptosis is a new necrosis pattern of hepatocyte during liver inflammation in acute liver failure (ALF). Histone deacetylase 2 (HDAC2) is associated with several pathological conditions in the liver system. The aim of this study is to inve
Externí odkaz:
https://doaj.org/article/525112b51a134b10b2ead47a69ba0371
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Previous research has revealed that the gut microbiome has a marked impact on acute liver failure (ALF). Here, we evaluated the impact of betaine on the gut microbiota composition in an ALF animal model. The potential protective effect of be
Externí odkaz:
https://doaj.org/article/500ddd5cb5704641849232d90fe882b8
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Trimethylamine-N-oxide (TMAO) is a molecular metabolite derived from the gut flora, which has recently emerged as a candidate risk factor for metabolic dysfunction-associated fatty liver disease (MAFLD). TMAO is mainly derived from gut, where the gut
Externí odkaz:
https://doaj.org/article/d6ff85092bf94c008bc87479e82bfb4f
Publikováno v:
IEEE Wireless Communications Letters. 12:21-25
Autor:
Luwen Wang, Yao Wang, Pan Cao, Zuojiong Gong, Qian Chen, Chunxia Shi, Fangzhou Jiao, Maohua Pei
Publikováno v:
Journal of Cellular and Molecular Medicine. 25:7218-7228
Acute liver failure (ALF) is a rare and critical medical condition. This study was designed to investigate the protective effects and underlying mechanism of ACY1215 in ALF mice. Our findings suggested that ACY1215 treatment ameliorates the pathologi
Autor:
Chunxia Shi, Maohua Pei, Yao Wang, Qian Chen, Pan Cao, Luyi Zhang, Jin Guo, Wei Deng, Luwen Wang, Xun Li, Zuojiong Gong
Publikováno v:
Biochemical and biophysical research communications. 594
Evidence shows that trimethylamine (TMA)/trimethylamine-N-oxide (TMAO) is closely related to non-alcoholic fatty liver disease (NAFLD). The conversion of TMA to TMAO is mainly catalyzed by flavin-containing monooxygenases 3 (FMO3) and FMO1. In this s
Publikováno v:
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Vol 8 (2021)
Frontiers in Molecular Biosciences, Vol 8 (2021)
Trimethylamine-N-oxide (TMAO) is a molecular metabolite derived from the gut flora, which has recently emerged as a candidate risk factor for metabolic dysfunction-associated fatty liver disease (MAFLD). TMAO is mainly derived from gut, where the gut
Autor:
Fangzhou Jiao, Maohua Pei, Yao Wang, Chunxia Shi, Jin Guo, Wei Deng, Qian Chen, Luwen Wang, Lu-Yi Zhang, Pan Cao, Zuojiong Gong
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology, Vol 12 (2021)
Chronic liver inflammation is a complex pathological process under different stress conditions, and the roles of stellate cells and macrophages in chronic liver inflammation have been widely reported. Moderate liver inflammation can protect the liver
Autor:
Fangzhou Jiao, Xun Li, Chunxia Shi, Zuojiong Gong, Yao Wang, Luwen Wang, Maohua Pei, Qian Chen
Publikováno v:
Journal of medical virologyREFERENCES. 93(11)
The aim of this study is to explore the relationship between liver pathological inflammation degree and pyroptosis in patients with chronic hepatitis B (CHB). One hundred and twenty CHB patients' liver tissue samples, including A0-A3 inflammatory gra
Autor:
Qian, Chen, Yao, Wang, Fangzhou, Jiao, Pan, Cao, Chunxia, Shi, Maohua, Pei, Luwen, Wang, Zuojiong, Gong
Publikováno v:
Journal of Cellular and Molecular Medicine
Acute liver failure (ALF) is a rare and critical medical condition. This study was designed to investigate the protective effects and underlying mechanism of ACY1215 in ALF mice. Our findings suggested that ACY1215 treatment ameliorates the pathologi