Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Maohua Cao"'
Autor:
Vijayalakshmi Sridharan, Kristin A Johnson, Reid D Landes, Maohua Cao, Preeti Singh, Gail Wagoner, Abdallah Hayar, Emily D Sprick, Kayla A Eveld, Anusha Bhattacharyya, Kimberly J Krager, Nukhet Aykin-Burns, Hartmut Weiler, Jose A Fernández, John H Griffin, Marjan Boerma
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0252142 (2021)
Accidental exposure to ionizing radiation may lead to delayed effects of acute radiation exposure (DEARE) in many organ systems. Activated protein C (APC) is a known mitigator of the acute radiation syndrome. To examine the role of APC in DEARE, we u
Externí odkaz:
https://doaj.org/article/50e75a3eea9247aa991916479ae21a30
Autor:
Bernadette Hritzo, Saeed Y. Aghdam, Betre Legesse, Amandeep Kaur, Maohua Cao, Marjan Boerma, Nabarun Chakraborty, George Dimitrov, Aarti Gautam, Rasha Hammamieh, William Wilkins, Alena Tsioplaya, Gregory P. Holmes-Hampton, Maria Moroni
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 3286 (2021)
Clinical, epidemiological, and experimental evidence demonstrate non-cancer, cardiovascular, and endocrine effects of ionizing radiation exposure including growth hormone deficiency, obesity, metabolic syndrome, diabetes, and hyperinsulinemia. Insuli
Externí odkaz:
https://doaj.org/article/a5e4a9e4f1e94c21b8b8f6bd9d93f3ef
Autor:
John W Seawright, Yusra Samman, Vijayalakshmi Sridharan, Xiao Wen Mao, Maohua Cao, Preeti Singh, Stepan Melnyk, Igor Koturbash, Gregory A Nelson, Martin Hauer-Jensen, Marjan Boerma
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180594 (2017)
PURPOSE:Space travel is associated with an exposure to low-dose rate ionizing radiation and the microgravity environment, both of which may lead to impairments in cardiac function. We used a mouse model to determine short- and long-term cardiac effec
Externí odkaz:
https://doaj.org/article/5c6f691e39ce4ac387ad3c9a6dc92d28
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104596 (2014)
Adeno-associated virus (AAV) (type 2) is a popular human gene therapy vector with a long active transgene expression period and no reported vector-induced adverse reactions. Yet the basic molecular biology of this virus has not been fully addressed.
Externí odkaz:
https://doaj.org/article/9f834d1bc0a444058320b9c9bf91aff2
Autor:
Hongqing Zhu, Maohua Cao, Leonardo Mirandola, Jose A Figueroa, Everardo Cobos, Maurizio Chiriva-Internati, Paul L Hermonat
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94665 (2014)
The development of gene therapy vectors for treating diseases of the cardiovascular system continues at a steady pace. Moreover, in the field of gene therapy the utility of "disease-specific promoters" has strong appeal. Many therapeutic genes, inclu
Externí odkaz:
https://doaj.org/article/06028fdcc81a4e369620e54f40b928f0
Publikováno v:
International Journal of Vascular Medicine, Vol 2012 (2012)
Both IL-10 and STAT3 are in the same signal transduction pathway, with IL-10-bound IL10 receptor (R) acting through STAT3 for anti-inflammatory effect. To investigate possible therapeutic synergism, we delivered both full-length wild-type human (h) S
Externí odkaz:
https://doaj.org/article/7e31e0529abe471e9eb31f846211d811
Autor:
Ashley S. Nemec-Bakk, Vijayalakshmi Sridharan, John W. Seawright, Gregory A. Nelson, Maohua Cao, Preeti Singh, Amrita K. Cheema, Bhaldev Singh, Yaoxiang Li, Igor Koturbash, Isabelle R. Miousse, Laura E. Ewing, Charles M. Skinner, Reid D. Landes, John D. Lowery, Xiao-Wen Mao, Sharda P. Singh, Marjan Boerma
Publikováno v:
Life Sciences in Space Research. 37:78-87
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2814ec1335bcac0c99aec3074cb988df
https://doi.org/10.1016/j.lssr.2023.03.008
https://doi.org/10.1016/j.lssr.2023.03.008
Autor:
Ashley S, Nemec-Bakk, Vijayalakshmi, Sridharan, Reid D, Landes, Preeti, Singh, Maohua, Cao, Paari, Dominic, John W, Seawright, Jeffery C, Chancellor, Marjan, Boerma
Publikováno v:
Life Sci Space Res (Amst)
PURPOSE: Astronauts in space vehicles beyond low-Earth orbit will be exposed to high charge and energy (HZE) ions and there is concern about potential adverse effects on the cardiovascular system. Thus far, most animal studies that assess cardiac eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c77627ec2d5139ec731bce2374315d44
https://doi.org/10.1016/j.lssr.2021.12.004
https://doi.org/10.1016/j.lssr.2021.12.004
Autor:
Vijayalakshmi Sridharan, Paari Dominic, John W. Seawright, Preeti Singh, Ashley S. Nemec-Bakk, Xingui Liu, Marjan Boerma, Rupak Pathak, Maohua Cao, Reid D. Landes, Guangrong Zheng
Publikováno v:
Life Sci Space Res (Amst)
Purpose: While there is concern about degenerative tissue effects of exposure to space radiation during deep-space missions, there are no pharmacological countermeasures against these adverse effects. γ-Tocotrienol (GT3) is a natural form of vitamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a70a020de9810a6fc4bd3d5a4ed69b85
https://doi.org/10.1016/j.lssr.2021.07.006
https://doi.org/10.1016/j.lssr.2021.07.006
Autor:
Xiao Wen Mao, Catherine M. Davis, Preeti Singh, Maohua Cao, Marjan Boerma, Sharda P. Singh, John W. Seawright, Gregory A. Nelson, Xin Zhang, Vijayalakshmi Sridharan, Reid D. Landes
Publikováno v:
Life Sci Space Res (Amst)
Purpose Studies are required to determine whether exposures to radiation encountered during manned missions in deep space may have adverse effects on the cardiovascular system. Most of the prior studies on effects of simulated space radiation on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0988d0357a4f216bbda23c7b355b3bf6
https://europepmc.org/articles/PMC7387753/
https://europepmc.org/articles/PMC7387753/
