Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Maofu, Fu"'
Autor:
Richard G. Pestell, Michael A. White, David Bregman, Hanzhou Lian, Robert G. Russell, Chris Albanese, Mahadev Rao, Maofu Fu, Kongming Wu, Mark D’Amico
Supplementary Figure 1 from The Inhibitor of Cyclin-Dependent Kinase 4a/Alternative Reading Frame (INK4a/ARF) Locus Encoded Proteins p16INK4a and p19ARF Repress Cyclin D1 Transcription through Distinct cis Elements
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a7fb2989a54d40a3e96582370aabdae
https://doi.org/10.1158/0008-5472.22363284.v1
https://doi.org/10.1158/0008-5472.22363284.v1
Autor:
Richard G. Pestell, Michael A. White, David Bregman, Hanzhou Lian, Robert G. Russell, Chris Albanese, Mahadev Rao, Maofu Fu, Kongming Wu, Mark D’Amico
The Ink4a/Arf locus encodes two structurally unrelated tumor suppressor proteins, p16INK4a and p14ARF (murine p19ARF). Invariant inactivation of either the p16INK4a-cyclin D/CDK-pRb pathway and/or p53-p14ARF pathway occurs in most human tumors. Cycli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eb25dcc1f74cd2abf0237a39426e3f6
https://doi.org/10.1158/0008-5472.c.6493638
https://doi.org/10.1158/0008-5472.c.6493638
Autor:
Richard G. Pestell, Michael A. White, David Bregman, Hanzhou Lian, Robert G. Russell, Chris Albanese, Mahadev Rao, Maofu Fu, Kongming Wu, Mark D’Amico
Supplementary Figure 2 from The Inhibitor of Cyclin-Dependent Kinase 4a/Alternative Reading Frame (INK4a/ARF) Locus Encoded Proteins p16INK4a and p19ARF Repress Cyclin D1 Transcription through Distinct cis Elements
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::283fd251dfe6380c7b602b514e6f33b1
https://doi.org/10.1158/0008-5472.22363281.v1
https://doi.org/10.1158/0008-5472.22363281.v1
Autor:
Maofu Fu, Jean H. Hoffman-Censits
Publikováno v:
Seminars in Oncology. 40:361-374
First-line therapy for men with metastatic or recurrent prostate cancer following definitive local therapy is medical or surgical castration. Though effective initially in most patients, the majority of tumors develop castration resistance, necessita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::877b641d17397efa46e94867847ab7cd
https://doi.org/10.1053/j.seminoncol.2013.04.015
https://doi.org/10.1053/j.seminoncol.2013.04.015
Autor:
Vladimir M. Popov, Richard T. Lee, Maofu Fu, Mathew C. Casimiro, Michael J. Powell, Jaime Lindsay, Francesco Marampon, Genichi Watanabe, Richard G. Pestell, Bianca M. Zani, Carmela Ciccarelli
Publikováno v:
Molecular Biology of the Cell. 19:2566-2578
The PC12 pheochromocytoma cell line responds to nerve growth factor (NGF) by exiting from the cell cycle and differentiating to induce extending neurites. Cyclin D1 is an important regulator of G1/S phase cell cycle progression, and it is known to pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41da60a879c0ad179228d41f18b8e021
https://doi.org/10.1091/mbc.e06-12-1110
https://doi.org/10.1091/mbc.e06-12-1110
Autor:
Anthony A. Sauve, Nagarajan Pattabiraman, Andrew A. Quong, Wei Gu, Maofu Fu, Tianle Yang, Xueping Zhang, Xuanmao Jiao, Fang Wang, Michael J. Powell, Chenguang Wang, Xiaofang Wu, Richard G. Pestell, Timothy G. Pestell, Maria Laura Avantaggiati, Manran Liu
Publikováno v:
Molecular and Cellular Biology. 26:8122-8135
The NAD-dependent histone deacetylase Sir2 plays a key role in connecting cellular metabolism with gene silencing and aging. The androgen receptor (AR) is a ligand-regulated modular nuclear receptor governing prostate cancer cellular proliferation, d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a2e94257e7007a1a663e199e0bbbaa
https://doi.org/10.1128/mcb.00289-06
https://doi.org/10.1128/mcb.00289-06
Publikováno v:
Annals of the New York Academy of Sciences. 1089:73-87
The position effect variegation in Drosophila and Schizosaccharomyces pombe, and higher-order chromatin structure regulation in yeast, is orchestrated by modifier genes of the Su(var) group, (e.g., histone deacetylases ([HDACs]), protein phosphatases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006d8fb3ab19280433630c875e631f84
https://doi.org/10.1196/annals.1386.047
https://doi.org/10.1196/annals.1386.047
Autor:
Zhiping Li, Runlei Du, Jianguo Yang, Sanjay Katiyar, Yinan Lu, Richard G. Pestell, Phyllis M. Novikoff, Chenguang Wang, Jennifer E. Leader, Andrew A. Quong, Maofu Fu
Publikováno v:
Proceedings of the National Academy of Sciences. 103:11567-11572
Cyclin D1 promotes nuclear DNA synthesis through phosphorylation and inactivation of the pRb tumor suppressor. Herein, cyclin D1 deficiency increased mitochondrial size and activity that was rescued by cyclin D1 in a Cdk-dependent manner. Nuclear res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168f3bb4fb8e74185fa6a1bdf066b0d5
https://doi.org/10.1073/pnas.0603363103
https://doi.org/10.1073/pnas.0603363103
Publikováno v:
Trends in Endocrinology & Metabolism. 17:186-191
Sirtuins (Sir2-related enzymes) are a recently discovered class of NAD(+)-dependent protein deacetylases that regulate gene expression in a variety of organisms by deacetylation of modified lysine residues on histones, transcription factors and other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7c20f08e464ac956618d4c3d3ce7a2a
https://doi.org/10.1016/j.tem.2006.04.002
https://doi.org/10.1016/j.tem.2006.04.002
Cyclin D1 Regulates Cellular Migration through the Inhibition of Thrombospondin 1 and ROCK Signaling
Autor:
Andrew A. Quong, Maofu Fu, Zhiping Li, Peter D. Burbelo, Xiaoming Ju, Chip Dye, Xueping Zhang, Jianguo Yang, Yinan Lu, Anping Li, Xuanmao Jiao, Chenguang Wang, Richard G. Pestell, E. Richard Stanley, Maozheng Dai
Publikováno v:
Molecular and Cellular Biology. 26:4240-4256
Cyclin D1 is overexpressed in human tumors, correlating with cellular metastasis, and is induced by activating Rho GTPases. Herein, cyclin D1-deficient mouse embryo fibroblasts (MEFs) exhibited increased adhesion and decreased motility compared with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dd28ccdbb788baa650906143b6da9b1
https://doi.org/10.1128/mcb.02124-05
https://doi.org/10.1128/mcb.02124-05