Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mao-Mao Gao"'
Autor:
Man Li Hu, Hong Jie Shi, Guo Jun Zhao, Mao Mao Gao, Lihua Zhu, Hongliang Li, Zhi-Gang She, Xiao-Jing Zhang, Yufeng Hu, Feng Jiao Hu, Chongshu Jian, Yan-Xiao Ji
Publikováno v:
Bioscience Reports
Aim: The study aims to evaluate protective effects of sophoricoside (Sop) on cardiac hypertrophy. Meanwhile, the potential and significance of Sop should be broadened and it should be considered as an attractive drug for the treatment of pathological
Autor:
Ling-Ping Zhao, Xiaozhan Wang, Yan Zhang, Yong Wang, Yue-Xin Lu, Zhi-Xiang Huang, Pi-Xiao Wang, Peng Zhang, Xiao-Jing Zhang, Yan-Xiao Ji, Feng Li, Zhi-Gang She, Zan Huang, Xueyong Zhu, Zhao Huan, Jun Gong, Mao-Mao Gao, Song Tian, David E. Cohen, Hongliang Li, Michele Alves-Bezerra, Xia Yang, Lin Cai, Lan Bai
Publikováno v:
Nature Medicine. 24:213-223
Nonalcoholic steatohepatitis (NASH) is a common clinical condition that can lead to advanced liver diseases. Lack of effective pharmacotherapies for NASH is largely attributable to an incomplete understanding of its pathogenesis. The deubiquitinase c
Autor:
Yan-Xiao Ji, Feng Li, Xin Zhang, Xia Yang, Xin-Liang Ma, Song Tian, Peng Zhang, Zhi-Gang She, Ling-Ping Zhao, Zan Huang, Yan Zhang, Jun Gong, Mao-Mao Gao, Hongliang Li, Yue-Xin Lu, Xiao-Jing Zhang, Pi-Xiao Wang, Zhihua Wang, Chun Fang, Xueyong Zhu
Publikováno v:
Nature Medicine. 24:84-94
Activation of apoptosis signal-regulating kinase 1 (ASK1) in hepatocytes is a key process in the progression of nonalcoholic steatohepatitis (NASH) and a promising target for treatment of the condition. However, the mechanism underlying ASK1 activati
Autor:
Jingjing Cai, Yongping Huang, Hongyu Nie, Junjie Zhou, Peng Zhang, Xu Cheng, Yan Che, Yan-Xiao Ji, Zhi-Gang She, Zan Huang, Xiao-Jing Zhang, Haibo Xu, Jiaqi Sun, Dan Liu, Mao-Mao Gao, Guo-Peng Chen, Hongliang Li, Rufang Liao
Publikováno v:
Cell metabolism. 31(4)
Nonalcoholic steatohepatitis (NASH) is an unmet clinical challenge due to the rapid increase in its occurrence but the lack of approved drugs to treat it. Further unraveling of the molecular mechanisms underlying NASH may identify potential successfu
Autor:
Fu-Han Gong, Xueyong Zhu, Zhi-Gang She, Wen-Lin Cheng, Juan-Juan Qin, Yan Zhang, Xia Li, Hao Xia, Hai-Ping Wang, Mao-Mao Gao
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 4, Pp 658-669 (2018)
Atherosclerosis is considered to be a chronic inflammatory disease that can lead to severe clinically important cardiovascular events. miR-150 is a small noncoding RNA that significantly enhances inflammatory responses by upregulating endothelial cel