Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Mao Amezawa"'
Autor:
Koustav Roy, Xuzhao Zhou, Rintaro Otani, Ping-Chuan Yuan, Shuji Ioka, Kaspar E. Vogt, Tamae Kondo, Nouran H. T. Farag, Haruto Ijiri, Zhaofa Wu, Youhei Chitose, Mao Amezawa, David S. Uygun, Yoan Cherasse, Hiroshi Nagase, Yulong Li, Masashi Yanagisawa, Manabu Abe, Radhika Basheer, Yi-Qun Wang, Tsuyoshi Saitoh, Michael Lazarus
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Optochemistry, an emerging pharmacologic approach in which light is used to selectively activate or deactivate molecules, has the potential to alleviate symptoms, cure diseases, and improve quality of life while preventing uncontrolled drug
Externí odkaz:
https://doaj.org/article/4431e78e019340f7971afef4a23b66d7
Autor:
Yang Lin, Koustav Roy, Shuji Ioka, Rintaro Otani, Mao Amezawa, Yukiko Ishikawa, Yoan Cherasse, Mahesh K. Kaushik, Daniela Klewe-Nebenius, Li Zhou, Masashi Yanagisawa, Yo Oishi, Tsuyoshi Saitoh, Michael Lazarus
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Insomnia is associated with psychiatric illnesses such as bipolar disorder or schizophrenia. Treating insomnia improves psychotic symptoms severity, quality of life, and functional outcomes. Patients with psychiatric disorders are often d
Externí odkaz:
https://doaj.org/article/54ec9a2e91c5458794cfece383912e6b
Autor:
Koustav Roy, Xuzhao Zhou, Rintaro Otani, Ping-Chuan Yuan, Shuji Ioka, Vogt, Kaspar E., Tamae Kondo, Farag, Nouran H. T., Haruto Ijiri, Zhaofa Wu, Youhei Chitose, Mao Amezawa, Uygun, David S., Yoan Cherasse, Hiroshi Nagase, Yulong Li, Masashi Yanagisawa, Manabu Abe, Basheer, Radhika, Yi-Qun Wang
Publikováno v:
Nature Communications; 4/30/2024, Vol. 15 Issue 1, p1-17, 17p, 6 Graphs
Autor:
Keita Iio, Kao Hashimoto, Yasuyuki Nagumo, Mao Amezawa, Taisei Hasegawa, Naoshi Yamamoto, Noriki Kutsumura, Katsuhiko Takeuchi, Yukiko Ishikawa, Hikari Yamamoto, Akihisa Tokuda, Tetsu Sato, Yasuo Uchida, Asuka Inoue, Ryuji Tanimura, Masashi Yanagisawa, Hiroshi Nagase, Tsuyoshi Saitoh
Publikováno v:
Journal of Medicinal Chemistry. 66:5453-5464
Autor:
Keita Iio, Kao Hashimoto, Yasuyuki Nagumo, Mao Amezawa, Taisei Hasegawa, Naoshi Yamamoto, Noriki Kutsumura, Katsuhiko Takeuchi, Yukiko Ishikawa, Masashi Yanagisawa, Hiroshi Nagase, Tsuyoshi Saitoh
Orexins are a family of neuropeptides that regulate various physiological events such as sleep/wakefulness as well as emotional and feeding behavior, and that act on two G-protein-coupled receptors, i.e., the orexin 1 (OX1R) and orexin 2 receptors (O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f64a7109c5d19265bba985eb11bf8b8
https://doi.org/10.26434/chemrxiv-2022-fxx2d
https://doi.org/10.26434/chemrxiv-2022-fxx2d
Autor:
Yang Lin, Koustav Roy, Shuji Ioka, Rintaro Otani, Mao Amezawa, Yukiko Ishikawa, Yoan Cherasse, Kaushik, Mahesh K., Klewe-Nebenius, Daniela, Li Zhou, Masashi Yanagisawa, Yo Oishi, Tsuyoshi Saitoh, Lazarus, Michael
Publikováno v:
Frontiers in Pharmacology; 2023, p1-17, 17p
Autor:
Mao Amezawa, Naoshi Yamamoto, Yasuyuki Nagumo, Noriki Kutsumura, Yukiko Ishikawa, Masashi Yanagisawa, Hiroshi Nagase, Tsuyoshi Saitoh
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 82:129151
Autor:
Keita Iio, Tsuyoshi Saitoh, Ryuichiro Ohshita, Tsubasa Hino, Mao Amezawa, Yoshiaki Takayama, Yasuyuki Nagumo, Naoshi Yamamoto, Noriki Kutsumura, Yoko Irukayama-Tomobe, Yukiko Ishikawa, Ryuji Tanimura, Masashi Yanagisawa, Hiroshi Nagase
Publikováno v:
Bioorganicmedicinal chemistry letters. 60
A novel series of 1-amino-tetralin derivatives were designed and synthesized based on the putative binding mode of the naphthalene-type orexin receptor agonist 5 and their agonist activities against orexin receptors were evaluated. The introduction o
Autor:
Noriki Kutsumura, Tsuyoshi Saitoh, Jumpei Horiuchi, Yukiko Ishikawa, Emi Hasegawa, Yasuyuki Nagumo, Masashi Yanagisawa, Takeshi Sakurai, Ryuji Tanimura, Hiroaki Gouda, Naoshi Yamamoto, Yasuhiro Ogawa, Akihisa Tokuda, Tetsu Sato, Yoko Irukayama-Tomobe, Mao Amezawa, Hiroshi Nagase, Ryuichiro Oshita, Yasuo Uchida
Structurally diverse small compounds are utilized to obtain hit compounds that have suitable pharmacophores in appropriate three-dimensional conformations for the target drug receptors. We have focused on the 1,3,5-trioxazatriquinane skeleton, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4079393b5fe25c5fc1566ec1c12834a
https://doi.org/10.33774/chemrxiv-2021-08md1
https://doi.org/10.33774/chemrxiv-2021-08md1
Autor:
Tsuyoshi Saitoh, Mao Amezawa, Jumpei Horiuchi, Yasuyuki Nagumo, Naoshi Yamamoto, Noriki Kutsumura, Ryuichiro Ohshita, Akihisa Tokuda, Yoko Irukayama-Tomobe, Yasuhiro Ogawa, Yukiko Ishikawa, Emi Hasegawa, Takeshi Sakurai, Yasuo Uchida, Tetsu Sato, Hiroaki Gouda, Ryuji Tanimura, Masashi Yanagisawa, Hiroshi Nagase
Structurally diverse small compounds are utilized to obtain hit compounds that have suitable pharmacophores in appropriate three-dimensional conformations for the target drug receptors. We have focused on the 1,3,5-trioxazatriquinane skeleton, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd0571529b5d14b8ad54e10a712a84a9
https://doi.org/10.26434/chemrxiv-2021-08md1
https://doi.org/10.26434/chemrxiv-2021-08md1