Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Manzhi, Zhao"'
Autor:
Weibin Li, Xinyi Yang, Chaojie Liu, Xu Liu, Lin Shi, Yingchao Zeng, Haohai Xia, Jia Li, Manzhi Zhao, Shifang Yang, Xiaojie Li, Bo Hu, Lianping Yang
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
ObjectivesThe emergency response to the COVID-19 pandemic may disrupt hospital management activities of antimicrobial resistance (AMR). This study aimed to determine the changing AMR trend over the period in China when stringent COVID-19 response mea
Externí odkaz:
https://doaj.org/article/1fb98a40d1f940038b6883ffd91c8299
Autor:
Haohai Xia, Jia Li, Xinyi Yang, Yingchao Zeng, Lin Shi, Weibin Li, Xu Liu, Shifang Yang, Manzhi Zhao, Jie Chen, Lianping Yang
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e32750- (2024)
Objectives: To evaluate the impact of pay-for-performance on antimicrobial consumption and antimicrobial expenditure in a large teaching hospital in Guangzhou, China. Methods: We collected data from hospital information system from January 2018 throu
Externí odkaz:
https://doaj.org/article/90bfaeb4ba3d4baabc351cfc38eaf31e
Autor:
Manzhi Zhao, Ling Li, Caoimhe H. Kiernan, Melisa D. Castro Eiro, Floris Dammeijer, Marjan van Meurs, Inge Brouwers-Haspels, Merel E. P. Wilmsen, Dwin G. B. Grashof, Harmen J. G. van de Werken, Rudi W. Hendriks, Joachim G. Aerts, Yvonne M. Mueller, Peter D. Katsikis
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Cytotoxic CD8 + T cell (CTL) exhaustion is driven by chronic antigen stimulation. Reversing CTL exhaustion with immune checkpoint blockade (ICB) has provided clinical benefits in different types of cancer. We, therefore, investigated whether
Externí odkaz:
https://doaj.org/article/894d1a0cf952487080d6943e463aba2e
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Macrophages (MΦs) are the most abundant leukocytes in mammalian ovaries that have heterogeneity and plasticity. A body of evidence has indicated that these cells are important in maintaining ovarian homeostasis and they play critical roles in ovaria
Externí odkaz:
https://doaj.org/article/ef951837e9474339b4b84eb09ce63283
Autor:
Ling Li, Manzhi Zhao, Caoimhe H. Kiernan, Melisa D. Castro Eiro, Marjan van Meurs, Inge Brouwers-Haspels, Merel E. P. Wilmsen, Dwin G. B. Grashof, Harmen J. G. van de Werken, Rudi W. Hendriks, Yvonne M. Mueller, Peter D. Katsikis
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionCytotoxic CD8+ T cell (CTL) exhaustion is a dysfunctional state of T cells triggered by persistent antigen stimulation, with the characteristics of increased inhibitory receptors, impaired cytokine production and a distinct transcriptiona
Externí odkaz:
https://doaj.org/article/3847fcbb75c24886b8cbbde00a41f92f
Autor:
Yingchao Zeng, Weibin Li, Manzhi Zhao, Jia Li, Xu Liu, Lin Shi, Xinyi Yang, Haohai Xia, Shifang Yang, Lianping Yang
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
IntroductionAntimicrobial resistance (AMR) of Klebsiella pneumoniae (K. pneumoniae) poses a significant global public health threat and is responsible for a high prevalence of infections and mortality. However, knowledge about how ambient temperature
Externí odkaz:
https://doaj.org/article/68ed36125355441ebfc5e7f62d676f5d
Autor:
Yvonne M. Mueller, Thijs J. Schrama, Rik Ruijten, Marco W. J. Schreurs, Dwin G. B. Grashof, Harmen J. G. van de Werken, Giovanna Jona Lasinio, Daniel Álvarez-Sierra, Caoimhe H. Kiernan, Melisa D. Castro Eiro, Marjan van Meurs, Inge Brouwers-Haspels, Manzhi Zhao, Ling Li, Harm de Wit, Christos A. Ouzounis, Merel E. P. Wilmsen, Tessa M. Alofs, Danique A. Laport, Tamara van Wees, Geoffrey Kraker, Maria C. Jaimes, Sebastiaan Van Bockstael, Manuel Hernández-González, Casper Rokx, Bart J. A. Rijnders, Ricardo Pujol-Borrell, Peter D. Katsikis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Developing predictive methods to identify patients with high risk of severe COVID-19 disease is of crucial importance. Authors show here that by measuring anti-SARS-CoV-2 antibody and cytokine levels at the time of hospital admission and integrating
Externí odkaz:
https://doaj.org/article/8868b5c6ee1046f79b63a7f738da79df
Autor:
Manzhi Zhao, Caoimhe H Kiernan, Christopher J Stairiker, Jennifer L Hope, Leticia G Leon, Marjan van Meurs, Inge Brouwers-Haspels, Ruben Boers, Joachim Boers, Joost Gribnau, Wilfred F J van IJcken, Eric M Bindels, Remco M Hoogenboezem, Stefan J Erkeland, Yvonne M Mueller, Peter D Katsikis
Publikováno v:
PLoS Pathogens, Vol 16, Iss 6, p e1008555 (2020)
Exhaustion is a dysfunctional state of cytotoxic CD8+ T cells (CTL) observed in chronic infection and cancer. Current in vivo models of CTL exhaustion using chronic viral infections or cancer yield very few exhausted CTL, limiting the analysis that c
Externí odkaz:
https://doaj.org/article/0638732910034e3dbdc1bc9fe44b7d9d
Autor:
Lin Shi, Weibin Li, Shifang Yang, Jia Li, Xu Liu, Yingchao Zeng, Haohai Xia, Xinyi Yang, Manzhi Zhao, Lianping Yang
Background Climate warming not only affects humans, megafauna and other flora but also the world’s microbial organisms. However, the relationship between ambient temperature and antimicrobial resistance (AMR) of important clinical bacteria is still
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b148599622f80d8d01e6f13e9cc3913c
https://doi.org/10.21203/rs.3.rs-2909911/v1
https://doi.org/10.21203/rs.3.rs-2909911/v1
Autor:
Jennifer L. Hope, Manzhi Zhao, Christopher J. Stairiker, Caoimhe H. Kiernan, Alison J. Carey, Yvonne M. Mueller, Marjan van Meurs, Inge Brouwers-Haspels, Dennis C. Otero, Eun-Ah Bae, Hannah A. Faso, Alex Maas, Hans de Looper, Paolo M. Fortina, Isidore Rigoutsos, Linda M. Bradley, Stefan J. Erkeland, Peter D. Katsikis
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950), 208(3), 603-617. American Association of Immunologists
MicroRNAs (miRNAs/miRs) are small, endogenous noncoding RNAs that are important post-transcriptional regulators with clear roles in the development of the immune system and immune responses. Using miRNA microarray profiling, we characterized the expr