Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Manyu Song"'
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Chronic stress leads to immunosuppression and induces splenocyte apoptosis. STAT3 is a transcription factor that regulates immunity and apoptosis; however, it is unclear whether the increased expression of phosphorylated STAT3 (p-STAT3) observed in c
Externí odkaz:
https://doaj.org/article/4c4d6d05c0244d8c8f26ed3973a80702
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Chronic stress is a key risk factor for depression, and microglia have been implicated in the pathogenesis of the disease. Recent studies show that the Nod-like receptor protein 3 (NLRP3) inflammasome is expressed in microglia and may play a crucial
Externí odkaz:
https://doaj.org/article/7c9e060d479e413aa79a3ee5db5b7bca
Autor:
Mengzhen Li, Xi Wu, Yuwei Pan, Manyu Song, Xu Yang, Jiuzhi Xu, Plikus, Maksim V., Cong Lv, Lu Yu, Zhengquan Yu
Publikováno v:
FASEB Journal; 3/15/2024, Vol. 38 Issue 5, p1-21, 21p
Autor:
Jiuyan Zhang, Yuan Zhao, Ning Sun, Manyu Song, Yongping Chen, Lin Li, Hailin Cui, Haotian Yang, Chuqiao Wang, Haiyang Zhang, Honggang Fan
Publikováno v:
Journal of agricultural and food chemistry. 70(9)
Chronic stress induction in immunosuppression and splenocyte apoptosis is commonly associated with increased susceptibility to various diseases. Lycopene (LYC) is a member of the carotenoid family with immune restoration and anti-apoptotic function.
Autor:
Manyu Song, Honggang Fan, Tianyuan Yang, Yuan Zhao, Wei Guan, Xiujing Feng, Yujie Yao, Chaoran Wang
Publikováno v:
Journal of Cellular Physiology. 234:18994-19009
Acute kidney injury (AKI) is a frequent and serious complication of sepsis; however, there are currently no effective therapies. Inflammation and oxidative stress are the major mechanisms implicated in lipopolysaccharide (LPS)-induced AKI. Dexmedetom
Autor:
Manyu Song, Jichen Sha, Xueyuan Hu, Honggang Fan, Xiujing Feng, Huayun Zhang, Yuan Zhao, Chaoran Wang
Publikováno v:
Toxicology and Applied Pharmacology. 364:144-152
Dexmedetomidine (DEX) protects against liver damage caused by sepsis. The purpose of this study was to confirm the regulatory effects of DEX on glycogen synthase kinase 3 beta (GSK-3β) via the α2 adrenergic receptor (α2AR) and evaluate the role of
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 11 (2020)
Frontiers in Physiology, Vol 11 (2020)
Chronic stress leads to immunosuppression and induces splenocyte apoptosis. STAT3 is a transcription factor that regulates immunity and apoptosis; however, it is unclear whether the increased expression of phosphorylated STAT3 (p-STAT3) observed in c
Publikováno v:
Toxicology. 429
LPS-induced neuronal apoptosis leads to neurodegenerative diseases (NDs). However, the mechanisms underlying NDs pathogenesis remains unclear. The apoptotic response to activation of the c-Myc/chloride intracellular channel (CLIC4) pathway is directe
Publikováno v:
Journal of cellular biochemistry. 120(10)
Dexmedetomidine (DEX) prevents kidney damage caused by sepsis, but the mechanism of this effect remains unclear. In this study, the protective molecular mechanism of DEX in lipopolysaccharide (LPS)-induced acute kidney injury was investigated and its
Autor:
Chaoran Wang, Biao Ma, Haotian Yang, Yuan Zhao, Li Luan, Yongping Chen, Manyu Song, Yujie Yao, Honggang Fan
Publikováno v:
Nitric oxide : biology and chemistry. 85
Increasing evidence has demonstrated that dexmedetomidine (DEX) possesses multiple pharmacological actions. Herein, we explored the protective effect and potential molecular mechanism of DEX on lipopolysaccharide (LPS)-induced early acute kidney inju