Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Manyu Du"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Methods to selectively manipulate specific long-distance chromosomal interactions are limited. Here the authors develop a method called Chemically Induced Chromosomal Interaction (CICI) to engineer interactions and demonstrate that 3D conformation pl
Externí odkaz:
https://doaj.org/article/817aff64194e4e13bb059c3d54dc919c
Publikováno v:
PLoS Genetics, Vol 13, Iss 4, p e1006736 (2017)
Recent Hi-C measurements have revealed numerous intra- and inter-chromosomal interactions in various eukaryotic cells. To what extent these interactions regulate gene expression is not clear. This question is particularly intriguing in budding yeast
Externí odkaz:
https://doaj.org/article/96869de426d449abb3cfe63e5ef51f42
Autor:
Vahid Asimi, Abhishek Sampath Kumar, Henri Niskanen, Christina Riemenschneider, Sara Hetzel, Julian Naderi, Nina Fasching, Niko Popitsch, Manyu Du, Helene Kretzmer, Zachary D. Smith, Raha Weigert, Maria Walther, Sainath Mamde, David Meierhofer, Lars Wittler, René Buschow, Bernd Timmermann, Ibrahim I. Cisse, Stefan L. Ameres, Alexander Meissner, Denes Hnisz
Publikováno v:
Nature Genetics
Most endogenous retroviruses (ERVs) in mammals are incapable of retrotransposition; therefore, why ERV derepression is associated with lethality during early development has been a mystery. Here, we report that rapid and selective degradation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aacb99499b9548036da3facfd0de18a
https://hdl.handle.net/21.11116/0000-000D-15FB-121.11116/0000-000D-15F9-3
https://hdl.handle.net/21.11116/0000-000D-15FB-121.11116/0000-000D-15F9-3
Publikováno v:
Nucleic Acids Research
Transcription factors (TFs) bind to specific sequences in DNA to regulate transcription. Despite extensive measurements of TFs’ dissociation constant (Kd) in vitro, their apparent Kdin vivo are usually unknown. LacI, a bacterial TF, is often used t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa5f0912206fe51f8f80300c05058ae4
https://doi.org/10.1093/nar/gkz698
https://doi.org/10.1093/nar/gkz698
Publikováno v:
Mol Cell Biol
The MET3 promoter (MET3pr) inserted into the silenced chromosome in budding yeast can overcome Sir2-dependent silencing upon induction and activate transcription in every single cell among a population. Despite the fact that MET3pr is turned on in al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8d52572e493a2cb8b78649e7af5f20
https://doi.org/10.1128/mcb.00146-19
https://doi.org/10.1128/mcb.00146-19
Publikováno v:
Current Genetics. 63:1017-1021
There are extensive long-distance chromosomal interactions in eukaryotic genomes, but to what extent these interactions affect gene expression is not clear. Recent works have identified several cases where clustering of co-regulated genes leads to en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d71b3eb3da976fb0b5034c075b2c2d62
https://doi.org/10.1007/s00294-017-0712-9
https://doi.org/10.1007/s00294-017-0712-9
Autor:
Xiaosong Li, Gang Ning, Hemant P. Yennawar, Manyu Du, Gregory C. Carter, Yu Liu, Lu Bai, Hongbin Liu, Conner A. Hoelzel, Kun Miao, Matthew Fares, Xin Zhang, Leeann S. Grainger, Hang Hu, Charles H. Wolstenholme
We present a fluorogenic method to visualize misfolding and aggregation of a specific protein-of-interest in live cells using structurally modulated fluorescent protein chromophores. Combining photo-physical analysis, X-ray crystallography, and theor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e49f0fd6cee387eca0714cffcb4c697
https://europepmc.org/articles/PMC6258209/
https://europepmc.org/articles/PMC6258209/
Publikováno v:
Molecular & Cellular Biology; Dec2019, Vol. 39 Issue 23, p1-14, 14p
Autor:
Yu Liu, Wolstenholme, Charles H., Carter, Gregory C., Hongbin Liu, Hang Hu, Grainger, Leeann S., Kun Miao, Fares, Matthew, Hoelzel, Conner A., Yennawar, Hemant P., Gang Ning, Manyu Du, Lu Bai, Xiaosong Li, Xin Zhang
Publikováno v:
Journal of the American Chemical Society; 6/20/2018, Vol. 140 Issue 24, p7381-7384, 4p