Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Manyu, Zhao"'
Autor:
Mengru Ma, Lian Yi, Yifei Pei, Qimin Zhang, Chao Tong, Manyu Zhao, Yuanhong Chen, Jinghan Zhu, Wanguang Zhang, Fan Yao, Pengyuan Yang, Peijing Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Despite recent advances in systemic therapy for hepatocellular carcinoma (HCC), the prognosis of hepatitis B virus (HBV)-induced HCC patients remains poor. By screening a sgRNA library targeting human deubiquitinases, we find that ubiquitin-
Externí odkaz:
https://doaj.org/article/d886e8719a9b478c86037c60372a1bfd
Autor:
Manyu Zhao, Liqun Wang, Mengzhu Wang, Shijie Zhou, Ying Lu, Huijie Cui, Alexandra C. Racanelli, Ling Zhang, Tinghong Ye, Bisen Ding, Ben Zhang, Jinliang Yang, Yuqin Yao
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-21 (2022)
Abstract Fibrosis is characterized by the excessive extracellular matrix deposition due to dysregulated wound and connective tissue repair response. Multiple organs can develop fibrosis, including the liver, kidney, heart, and lung. Fibrosis such as
Externí odkaz:
https://doaj.org/article/8f258342cf4047a987ea70b05d80f6a6
Publikováno v:
IEEE Access, Vol 10, Pp 120168-120180 (2022)
With the rapid development of the social economy, the problem of environmental pollution has been widely concerned. The existing environmental monitoring system adopts a hierarchical centralized management structure, which has some problems, such as
Externí odkaz:
https://doaj.org/article/7494bea0997047e9bd4d912b6679fc73
Autor:
Hong Luo, Zhicheng Zhou, Shan Huang, Mengru Ma, Manyu Zhao, Lixu Tang, Yuan Quan, Yiming Zeng, Li Su, Jongchan Kim, Peijing Zhang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 9, Pp 1-11 (2021)
Abstract Failures to treat triple-negative breast cancer (TNBC) are mainly due to chemoresistance or radioresistance. We and others previously discovered that zinc finger E-box-binding homeobox 1 (ZEB1) is a massive driver causing these resistance. H
Externí odkaz:
https://doaj.org/article/e0370f7927b8463da4664cc131f97ea0
Publikováno v:
IEEE Access, Vol 9, Pp 54639-54648 (2021)
To realize the unmanned automation of the full mechanized caving, the bottleneck problem of coal-gangue interface detection in top coal caving must be solved first. Targeting coal-gangue interface detection on fully mechanized mining face, an alterna
Externí odkaz:
https://doaj.org/article/ecc5ae25704144fc92bc448851cc25d1
Autor:
Yuqin Yao, Zhuowei Liu, Manyu Zhao, Zhengxia Chen, Peng Li, Yang Zhang, Yuxi Wang, Chengjian Zhao, Chaofeng Long, Xiaoxin Chen, Jinliang Yang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 8, Pp 1453-1475 (2020)
Angiokinases, such as vascular endothelial-, fibroblast- and platelet-derived growth factor receptors (VEGFRs, FGFRs and PDGFRs) play crucial roles in tumor angiogenesis. Anti-angiogenesis therapy using multi-angiokinase inhibitor has achieved great
Externí odkaz:
https://doaj.org/article/38f72e4cdef544ae9c588050f698cbf3
Autor:
Xiaoxin Chen, Qinhai Ma, Manyu Zhao, Yuqin Yao, Qianru Zhang, Miao Liu, Zifeng Yang, Wenbin Deng
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 365 (2023)
The influenza A virus is highly contagious and often causes global pandemics. The prevalence of strains of the influenza A virus that are resistant to approved drugs is a huge challenge for the current clinical treatment of influenza A. RNA polymeras
Externí odkaz:
https://doaj.org/article/2d62100e7b1d4c1baf90418b544071ae
Publikováno v:
Agriculture, Vol 12, Iss 11, p 1929 (2022)
Assessing the quality of agricultural products is an essential step to reduce food waste. The problems of overly complex models, difficult to deploy to mobile devices, and slow real-time detection in the application of deep learning in agricultural p
Externí odkaz:
https://doaj.org/article/ec73fbd553b84589832e1426670b6b5e
Autor:
Ying Lu, Mengzhu Wang, Manyu Zhao, Qianru Zhang, Rui Qian, Zan Hu, Qi Ke, Lin Yu, Liqun Wang, Qinhuai Lai, Zhenmi Liu, Xia Jiang, Ben Zhang, Jinliang Yang, Yuqin Yao
Publikováno v:
Biochemical and Biophysical Research Communications. 653:93-101
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec6b90a761b383005b52c410a9ea4160
https://doi.org/10.1016/j.bbrc.2023.02.048
https://doi.org/10.1016/j.bbrc.2023.02.048
Autor:
Linfu Liu, Chuang Liu, Manyu Zhao, Qianru Zhang, Ying Lu, Ping Liu, Hua Yang, Jinliang Yang, Xiaoxin Chen, Yuqin Yao
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243911 (2020)
Peroxisome proliferator-activated receptor α/δ (PPAR α/δ), regulating glucolipid metabolism and immune inflammation, has been identified as an effective therapeutic target in non-alcoholic steatohepatitis (NASH). Dual PPAR α/δ agonist, such as
Externí odkaz:
https://doaj.org/article/001cd9c22611439d8f3c3e95d8b9971f