Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Manya Sabherwal"'
Autor:
Joel D A Tyndall, Manya Sabherwal, Alia A Sagatova, Mikhail V Keniya, Jacopo Negroni, Rajni K Wilson, Matthew A Woods, Klaus Tietjen, Brian C Monk
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167485 (2016)
Azole antifungals, known as demethylase inhibitors (DMIs), target sterol 14α-demethylase (CYP51) in the ergosterol biosynthetic pathway of fungal pathogens of both plants and humans. DMIs remain the treatment of choice in crop protection against a w
Externí odkaz:
https://doaj.org/article/ecc5305817ae4a19aa6dae4d47d44614
Autor:
Minh Ha, Manya Sabherwal, Elizabeth Duncan, Stewart Stevens, Peter Stockwell, Michelle McConnell, Alaa El-Din Bekhit, Alan Carne
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139774 (2015)
An in-depth proteomic study of sheep milk whey is reported and compared to the data available in the literature for the cow whey proteome. A combinatorial peptide ligand library kit (ProteoMiner) was used to normalize protein abundance in the sheep w
Externí odkaz:
https://doaj.org/article/167d652c5269473eae501c6c90a3f040
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106465 (2014)
A previously uncharacterized protein with a carotenoid-binding function has been isolated and characterized from the gonad of the New Zealand sea urchin Evechinus chloroticus. The main carotenoid bound to the protein was determined by reversed phase-
Externí odkaz:
https://doaj.org/article/f0021c27a1214c469c70669ec53a0ccc
Autor:
Mikhail V. Keniya, Harith F. Hassan, Rajni K. Wilson, Brian C. Monk, Danyon O. Graham, Manya Sabherwal, Joel D. A. Tyndall, Danni Chen
Publikováno v:
Antimicrobial Agents and Chemotherapy. 63
Tetrazole antifungals designed to target fungal lanosterol 14α-demethylase (LDM) appear to be effective against a range of fungal pathogens. In addition, a crystal structure of the catalytic domain of Candida albicans LDM in complex with the tetrazo
Autor:
Mikhail V. Keniya, Brian C. Monk, Manya Sabherwal, Joel D. A. Tyndall, Rajni K. Wilson, Alia A. Sagatova, Matthew A. Woods
Targeting lanosterol 14α-demethylase (LDM) with azole drugs provides prophylaxis and treatments for superficial and disseminated fungal infections, but cure rates are not optimal for immunocompromised patients and individuals with comorbidities. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ffb49ea97e4543c1a09084e4be2874
https://europepmc.org/articles/PMC6201081/
https://europepmc.org/articles/PMC6201081/
Autor:
Brian C. Monk, Manya Sabherwal, Rajni K. Wilson, Joel D. A. Tyndall, Mikhail V. Keniya, Alia A. Sagatova
Publikováno v:
Scientific Reports
Emergence of fungal strains showing resistance to triazole drugs can make treatment of fungal disease problematic. Triazole resistance can arise due to single mutations in the drug target lanosterol 14α-demethylase (Erg11p/CYP51). We have determined
Autor:
Matthew A. Woods, Klaus Tietjen, Mikhail V. Keniya, Jacopo Negroni, Brian C. Monk, Manya Sabherwal, Joel D. A. Tyndall, Alia A. Sagatova, Rajni K. Wilson
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167485 (2016)
PLoS ONE
PLoS ONE
Azole antifungals, known as demethylase inhibitors (DMIs), target sterol 14α-demethylase (CYP51) in the ergosterol biosynthetic pathway of fungal pathogens of both plants and humans. DMIs remain the treatment of choice in crop protection against a w
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 9, p e106465 (2014)
PLoS ONE, Vol 9, Iss 9, p e106465 (2014)
A previously uncharacterized protein with a carotenoid-binding function has been isolated and characterized from the gonad of the New Zealand sea urchin Evechinus chloroticus. The main carotenoid bound to the protein was determined by reversed phase-