Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Manxiang Zhu"'
Publikováno v:
Engineering Microbiology, Vol 4, Iss 1, Pp 100121- (2024)
Natural product biosynthesis is controlled at multiple levels. Characterization of naturally occurring promoters has facilitated the study of the synthetic biology of natural products. Herein, we report the discovery of two high-yield actinomycin D (
Externí odkaz:
https://doaj.org/article/451d1e66a2334110a974bca3b7a10d59
Publikováno v:
Microbial Cell Factories, Vol 21, Iss 1, Pp 1-11 (2022)
Abstract Background The anthraquinone-fused 10-membered enediynes (AFEs), represented by tiancimycins (TNMs), possess a unique structural feature and promising potentials as payloads of antitumor antibody–drug conjugates. Despite many efforts, the
Externí odkaz:
https://doaj.org/article/db7d1f6315854f2f9f6d70f86b72a230
Publikováno v:
ACS Synthetic Biology. 9:1460-1467
The complex life cycle of streptomycetes is closely related to their secondary metabolisms, all controlled by cascade regulations. Tiancimycins (TNMs) are ten-membered enediynes possessing great potential for antitumor drug development. However, thei
Autor:
Fan, Zhang, Die, Gao, Jing, Lin, Manxiang, Zhu, Zhoukang, Zhuang, Yanwen, Duan, Xiangcheng, Zhu
Publikováno v:
ACS synthetic biology. 9(6)
The complex life cycle of streptomycetes is closely related to their secondary metabolisms, all controlled by cascade regulations. Tiancimycins (TNMs) are ten-membered enediynes possessing great potential for antitumor drug development. However, thei