Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Manvendra K, Singh"'
Autor:
Huimei Chen, Gabriel Chew, Nithya Devapragash, Jui Zhi Loh, Kevin Y. Huang, Jing Guo, Shiyang Liu, Elisabeth Li Sa Tan, Shuang Chen, Nicole Gui Zhen Tee, Masum M. Mia, Manvendra K. Singh, Aihua Zhang, Jacques Behmoaras, Enrico Petretto
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Non-ischemic cardiomyopathy is a severe disease, characterized by interstitial fibrosis in the left ventricle of the heart. Here authors show that the E3 ubiquitin ligase WWP2 plays a pathogenic role in heart fibrosis via regulating a distinct monocy
Externí odkaz:
https://doaj.org/article/04ab9cd1a1a34c4da30eb9e5180335f7
Autor:
Masum M. Mia, Manvendra K. Singh
Publikováno v:
Cells, Vol 11, Iss 13, p 2065 (2022)
Fibrosis results from defective wound healing processes often seen after chronic injury and/or inflammation in a range of organs. Progressive fibrotic events may lead to permanent organ damage/failure. The hallmark of fibrosis is the excessive accumu
Externí odkaz:
https://doaj.org/article/6fc6af9160804e7b9bcc961f2f31d4fc
Autor:
Kazuaki Maruyama, Kazuaki Naemura, Yuichiro Arima, Yasunobu Uchijima, Hiroaki Nagao, Kenji Yoshihara, Manvendra K. Singh, Akiyoshi Uemura, Fumio Matsuzaki, Yutaka Yoshida, Yukiko Kurihara, Sachiko Miyagawa-Tomita, Hiroki Kurihara
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102305- (2021)
Summary: Blood and lymphatic vessels surrounding the heart develop through orchestrated processes from cells of different origins. In particular, cells around the outflow tract which constitute a primordial transient vasculature, referred to as aorti
Externí odkaz:
https://doaj.org/article/b38903fdfe96445f8df53c27264b41b4
Autor:
Kathleen Wung Bi-Lin, Pratap Veerabrahma Seshachalam, Tran Tuoc, Anastassia Stoykova, Sujoy Ghosh, Manvendra K Singh
Publikováno v:
PLoS Genetics, Vol 17, Iss 3, p e1009446 (2021)
The BAF complex plays an important role in the development of a wide range of tissues by modulating gene expression programs at the chromatin level. However, its role in neural crest development has remained unclear. To determine the role of the BAF
Externí odkaz:
https://doaj.org/article/bd548854d7df44e38e9b809177eb113f
Autor:
Masum M Mia, Dasan Mary Cibi, Siti Aishah Binte Abdul Ghani, Weihua Song, Nicole Tee, Sujoy Ghosh, Junhao Mao, Eric N Olson, Manvendra K Singh
Publikováno v:
PLoS Biology, Vol 18, Iss 12, p e3000941 (2020)
Adverse cardiac remodeling after myocardial infarction (MI) causes structural and functional changes in the heart leading to heart failure. The initial post-MI pro-inflammatory response followed by reparative or anti-inflammatory response is essentia
Externí odkaz:
https://doaj.org/article/2bc203870dab44819cda8ae48759bdea
Autor:
Dasan Mary Cibi, Kathleen Wung Bi-Lin, Shamini Guna Shekeran, Reddemma Sandireddy, Nicole Tee, Anamika Singh, Yajun Wu, Dinesh Kumar Srinivasan, Jean-Paul Kovalik, Sujoy Ghosh, Patrick Seale, Manvendra K. Singh
Publikováno v:
Cell Reports, Vol 33, Iss 3, Pp 108288- (2020)
Summary: Hypertrophic cardiomyopathy (HCM) is a well-established risk factor for cardiovascular mortality worldwide. Although hypertrophy is traditionally regarded as an adaptive response to physiological or pathological stress, prolonged hypertrophy
Externí odkaz:
https://doaj.org/article/1aade85b19c14a27ac9367841f5fd88b
Autor:
Madhulika Tripathi, Brijesh Kumar Singh, Jin Zhou, Keziah Tikno, Anissa Widjaja, Reddemma Sandireddy, Kabilesh Arul, Siti Aishah Binte Abdul Ghani, George Goh Boon Bee, Kiraely Adam Wong, Ho Jia Pei, Shamini Guna Shekeran, Rohit Anthony Sinha, Manvendra K. Singh, Stuart Alexander Cook, Ayako Suzuki, Teegan Reina Lim, Chang-Chuen Cheah, Jue Wang, Rui-Ping Xiao, Xiuqing Zhang, Pierce Kah Hoe Chow, Paul Michael Yen
Publikováno v:
Journal of Hepatology. 77:1246-1255
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cdeeb15d918f2f01f10879161aae177
https://doi.org/10.1016/j.jhep.2022.06.033
https://doi.org/10.1016/j.jhep.2022.06.033
Autor:
Masum M. Mia, Manvendra K. Singh
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Heart disease continues to be the leading cause of morbidity and mortality worldwide. Cardiac malformation during development could lead to embryonic or postnatal death. However, matured heart tissue has a very limited regenerative capacity. Thus, lo
Externí odkaz:
https://doaj.org/article/b42819c25a044e379449db641bcbca42
Autor:
Dasan Mary Cibi, Masum M Mia, Shamini Guna Shekeran, Lim Sze Yun, Reddemma Sandireddy, Priyanka Gupta, Monalisa Hota, Lei Sun, Sujoy Ghosh, Manvendra K Singh
Publikováno v:
eLife, Vol 8 (2019)
Alternative splicing (AS) creates proteomic diversity from a limited size genome by generating numerous transcripts from a single protein-coding gene. Tissue-specific regulators of AS are essential components of the gene regulatory network, required
Externí odkaz:
https://doaj.org/article/affddb8f910c4c8e8b0e4a595711c167
Autor:
Masum M. Mia, Siti Aishah Binte Abdul Ghani, Dasan Mary Cibi, Hanumakumar Bogireddi, Wai Shiu Fred Wong, Manvendra K. Singh
Pulmonary fibrosis (PF) is the most common form of end stage interstitial devastating lung disease characterized by the scarring of lung due to excessive production of extracellular matrix (ECM). Recent studies have revealed the impact of macrophages
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d33af186e967480db8af2d1996411975
https://doi.org/10.1101/2023.05.24.542136
https://doi.org/10.1101/2023.05.24.542136
