Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Manveen K. Sethi"'
Autor:
Darukeshwara Joladarashi, Charan Thej, Vandana Mallaredy, Ajit Magadum, Maria Cimini, Carolina Gonzalez, May Truongcao, Joseph T. Nigro, Manveen K. Sethi, Andrew A. Gibb, Cindy Benedict, Walter J. Koch, Raj Kishore
Publikováno v:
iScience, Vol 27, Iss 10, Pp 111021- (2024)
Summary: Mesenchymal stromal cells (MSC) are promising stem cell therapy for treating cardiovascular and other degenerative diseases. Diabetes affects the functional capability of MSC and impedes cell-based therapy. Despite numerous studies, the impa
Externí odkaz:
https://doaj.org/article/3a9a8135cbdf48ae9273925cf1080a09
Autor:
Gabriele Chelini, Hadi Mirzapourdelavar, Peter Durning, David Baidoe-Ansah, Manveen K. Sethi, Sinead M. O’Donovan, Torsten Klengel, Luigi Balasco, Cristina Berciu, Anne Boyer-Boiteau, Robert McCullumsmith, Kerry J. Ressler, Joseph Zaia, Yuri Bozzi, Alexander Dityatev, Sabina Berretta
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114112- (2024)
Summary: Recent findings show that effective integration of novel information in the brain requires coordinated processes of homo- and heterosynaptic plasticity. In this work, we hypothesize that activity-dependent remodeling of the peri-synaptic ext
Externí odkaz:
https://doaj.org/article/21eb77a4d1ef4429b4c1a9780261c8f6
Publikováno v:
MethodsX, Vol 6, Iss , Pp 2329-2347 (2019)
We describe a protocol for glycomic and proteomic profiling that uses serial enzyme digestions from the surface of fresh frozen or fixed tissue slides. The abundances of the extracted glycans and peptides are determined using liquid chromatography-ma
Externí odkaz:
https://doaj.org/article/146f2c9d7d9848e1b31ee5affd3b9e96
Autor:
Jihuan Chen, Tomoya Kawamura, Manveen K. Sethi, Joseph Zaia, Vez Repunte-Canonigo, Pietro Paolo Sanna
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Abstract Substance abuse is a pressing problem with few therapeutic options. The identification of addiction resilience factors is a potential strategy to identify new mechanisms that can be targeted therapeutically. Heparan sulfate (HS) is a linear
Externí odkaz:
https://doaj.org/article/00157ec978ec40258256ee7bb42d115d
Autor:
Manveen K. Sethi, Susan Fanayan
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 12, Pp 29278-29304 (2015)
Colorectal cancer (CRC) is one of the most prevalent cancers worldwide. An increased molecular understanding of the CRC pathology is warranted to gain insights into the underlying molecular and cellular mechanisms of the disease. Altered protein glyc
Externí odkaz:
https://doaj.org/article/2e1ce07335b246be91c839245d856fdc
Autor:
Roger Higdon, Jessie Kala, Devan Wilkins, Julia Fangfei Yan, Manveen K. Sethi, Liang Lin, Siqi Liu, Elizabeth Montague, Imre Janko, John Choiniere, Natali Kolker, William S. Hancock, Eugene Kolker, Susan Fanayan
Publikováno v:
Proteomes, Vol 5, Iss 1, p 5 (2017)
Medulloblastoma (MB) is the most common malignant pediatric brain tumor. Patient survival has remained largely the same for the past 20 years, with therapies causing significant health, cognitive, behavioral and developmental complications for those
Externí odkaz:
https://doaj.org/article/98c76ada1e1f48e199ff1afa975ddbf0
Publikováno v:
Anal Bioanal Chem
Extracellular matrix (ECM) proteins, collectively known as the matrisome, include collagens, glycoproteins, and proteoglycans. Alterations in the matrisome have been implicated in the neurodegenerative pathologies including Parkinson’s disease (PD)
Publikováno v:
Mass Spectrometry Reviews.
The brain extracellular matrix (ECM) is a highly glycosylated environment and plays important roles in many processes including cell communication, growth factor binding, and scaffolding. The formation of structures such as perineuronal nets (PNNs) i
Autor:
Zhi Ruan, Satoshi Muraoka, Jina Ko, Yang You, David Issadore, Howard E. Gendelman, Yuzhi Wang, Joseph Zaia, Kayo Yukawa-Takamatsu, Annina M. DeLeo, John D. Hogan, Manveen K. Sethi, Tsuneya Ikezu, Mei Chen, Maria Medalla, Zijian Yang, Seiko Ikezu, Santhi Gorantla, Weiming Xia
Publikováno v:
Alzheimers Dement
IntroductionExtracellular vesicles (EVs) from human Alzheimer’s disease (AD) biospecimens contain amyloid-β peptide (Aβ) and tau. While AD EVs are known to affect brain disease pathobiology, their biochemical and molecular characterizations remai
Publikováno v:
MethodsX
MethodsX, Vol 6, Iss, Pp 2329-2347 (2019)
MethodsX, Vol 6, Iss, Pp 2329-2347 (2019)
Graphical abstract
We describe a protocol for glycomic and proteomic profiling that uses serial enzyme digestions from the surface of fresh frozen or fixed tissue slides. The abundances of the extracted glycans and peptides are determined using
We describe a protocol for glycomic and proteomic profiling that uses serial enzyme digestions from the surface of fresh frozen or fixed tissue slides. The abundances of the extracted glycans and peptides are determined using