Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Manuele G Muraro"'
Autor:
Elena Groppa, Sime Brkic, Emmanuela Bovo, Silvia Reginato, Veronica Sacchi, Nunzia Di Maggio, Manuele G Muraro, Diego Calabrese, Michael Heberer, Roberto Gianni‐Barrera, Andrea Banfi
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 10, Pp 1366-1384 (2015)
Abstract VEGF is widely investigated for therapeutic angiogenesis, but while short‐term delivery is desirable for safety, it is insufficient for new vessel persistence, jeopardizing efficacy. Here, we investigated whether and how VEGF dose regulate
Externí odkaz:
https://doaj.org/article/f11a307f5cd043eba289efaf7efd7624
Autor:
Giulio C. Spagnoli, Luigi Terracciano, Luigi Tornillo, Markus Zuber, Giuseppe Sconocchia, Paul Zajac, Chantal Mengus, Manuele G. Muraro, Michel Adamina, Urs von Holzen, Daniel Oertli, Martin Bolli, Raffaele Rosso, Raoul A. Droeser, Basilio Angrisani, Elisabetta Padovan, Xaver Huber, Eleonora Cremonesi, Francesca Amicarella, Christian Hirt, Giandomenica Iezzi, Serenella Eppenberger-Castori, Junyi Han, Christian A. Nebiker
PDF - 480K, CX3CL1/fractalkine gene and protein expression in healthy colon mucosa, CRC and established cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56bd66cd0fa587d5d6ea72b377f4d270
https://doi.org/10.1158/1078-0432.22451705
https://doi.org/10.1158/1078-0432.22451705
Autor:
Giulio C. Spagnoli, Luigi Terracciano, Luigi Tornillo, Markus Zuber, Giuseppe Sconocchia, Paul Zajac, Chantal Mengus, Manuele G. Muraro, Michel Adamina, Urs von Holzen, Daniel Oertli, Martin Bolli, Raffaele Rosso, Raoul A. Droeser, Basilio Angrisani, Elisabetta Padovan, Xaver Huber, Eleonora Cremonesi, Francesca Amicarella, Christian Hirt, Giandomenica Iezzi, Serenella Eppenberger-Castori, Junyi Han, Christian A. Nebiker
PDF - 216K, Notch Box plot of histoscore values in CRC TMA upon staining with GM-CSF and M-CSF specific reagents.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4848a7523e2ee3c07d64e901fa6c988a
https://doi.org/10.1158/1078-0432.22451708
https://doi.org/10.1158/1078-0432.22451708
Data from GM-CSF Production by Tumor Cells Is Associated with Improved Survival in Colorectal Cancer
Autor:
Giulio C. Spagnoli, Luigi Terracciano, Luigi Tornillo, Markus Zuber, Giuseppe Sconocchia, Paul Zajac, Chantal Mengus, Manuele G. Muraro, Michel Adamina, Urs von Holzen, Daniel Oertli, Martin Bolli, Raffaele Rosso, Raoul A. Droeser, Basilio Angrisani, Elisabetta Padovan, Xaver Huber, Eleonora Cremonesi, Francesca Amicarella, Christian Hirt, Giandomenica Iezzi, Serenella Eppenberger-Castori, Junyi Han, Christian A. Nebiker
Purpose: Colorectal cancer infiltration by CD16+ myeloid cells correlates with improved prognosis. We addressed mechanistic clues and gene and protein expression of cytokines potentially associated with macrophage polarization.Experimental Design: GM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e6b516b4eb856019f073f749a40dc19
https://doi.org/10.1158/1078-0432.c.6522260.v1
https://doi.org/10.1158/1078-0432.c.6522260.v1
Autor:
Gordian Born, Evelia Plantier, Guido Nannini, Alessandro Caimi, Andrea Mazzoleni, M. Adelaide Asnaghi, Manuele G. Muraro, Arnaud Scherberich, Ivan Martin, Andrés García‐García
Publikováno v:
Biotechnology journalREFERENCES.
Bioreactors enabling direct perfusion of cell suspensions or culture media through the pores of 3D scaffolds have long been used in tissue engineering to improve cell seeding efficiency as well as uniformity of cell distribution and tissue developmen
Ex-vivo assessment of drug response on breast cancer primary tissue with preserved microenvironments
Autor:
Manuele G. Muraro, Simone Muenst, Valentina Mele, Luca Quagliata, Giandomenica Iezzi, Alexandar Tzankov, Walter P. Weber, Giulio C. Spagnoli, Savas D. Soysal
Publikováno v:
OncoImmunology, Vol 6, Iss 7 (2017)
Interaction between cancerous, non-transformed cells, and non-cellular components within the tumor microenvironment plays a key role in response to treatment. However, short-term culture or xenotransplantation of cancer specimens in immunodeficient a
Externí odkaz:
https://doaj.org/article/f34bfbb8817f415dbbedb029144cde87
Autor:
Tala Shekarian, Carl P. Zinner, Ewelina M. Bartoszek, Wandrille Duchemin, Anna T. Wachnowicz, Sabrina Hogan, Manina M. Etter, Julia Flammer, Chiara Paganetti, Tomás A. Martins, Philip Schmassmann, Steven Zanganeh, Francois Le Goff, Manuele G. Muraro, Marie-Françoise Ritz, Darci Phillips, Salil S. Bhate, Graham L. Barlow, Garry P. Nolan, Christian M. Schürch, Gregor Hutter
Publikováno v:
Science advances. 8(26)
Recent therapeutic strategies for glioblastoma (GBM) aim at targeting immune tumor microenvironment (iTME) components to induce antitumoral immunity. A patient-tailored, ex vivo drug testing and response analysis platform for GBM would facilitate per
Autor:
Valentina Mele, Camilla Basso, Valeria Governa, Jesus F. Glaus Garzon, Manuele G. Muraro, Silvio Däster, Christian A. Nebiker, Robert Mechera, Martin Bolli, Alexander Schmidt, Roger Geiger, Giulio C. Spagnoli, Dimitri Christoforidis, Pietro E. Majno, Lubor Borsig, Giandomenica Iezzi
Publikováno v:
Cancers; Volume 14; Issue 8; Pages: 2024
Stromal infiltration is associated with poor prognosis in human colon cancers. However, the high heterogeneity of human tumor-associated stromal cells (TASCs) hampers a clear identification of specific markers of prognostic relevance. To address thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fcc34587dcf544ea23c1d567cfebdcb
Autor:
Federica Foglietta, Manuele G. Muraro, Chantal Mengus, Giulio C. Spagnoli, Simone Muenst, Celeste Manfredonia, Valentina Mele, Giandomenica Iezzi, Francesca Amicarella, Savas D. Soysal
Publikováno v:
ACS biomaterials scienceengineering. 4(2)
Immunotherapy has emerged during the past two decades as an innovative and successful form of cancer treatment. However, frequently, mechanisms of actions are still unclear, predictive markers are insufficiently characterized, and preclinical assays
Autor:
Zihe Huo, Remo Bilang, Claudiu T. Supuran, Nicolas von der Weid, Elisabeth Bruder, Stefan Holland-Cunz, Ivan Martin, Manuele G. Muraro, Stephanie J. Gros
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 6; Pages: 3128
Neuroblastoma is a rare disease. Rare are also the possibilities to test new therapeutic options for neuroblastoma in clinical trials. Despite the constant need to improve therapy and outcomes for patients with advanced neuroblastoma, clinical trials