Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Manuela Voltattorni"'
Autor:
Giovanna Farruggia, Lorenzo Anconelli, Lucrezia Galassi, Manuela Voltattorni, Martina Rossi, Pietro Lodeserto, Paolo Blasi, Isabella Orienti
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Acute promyelocytic leukemia (APL) is characterized by rearrangements of the retinoic acid receptor, RARα, which makes all-trans retinoic acid (ATRA) highly effective in the treatment of this disease, inducing promyelocytes differentiation.
Externí odkaz:
https://doaj.org/article/4a10973b0c8341c9a383e4eb39c2a3e7
Autor:
Lucrezia Galassi, Martina Rossi, Pietro Lodeserto, Monia Lenzi, Francesca Borsetti, Manuela Voltattorni, Giovanna Farruggia, Paolo Blasi, Isabella Orienti
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 648 (2023)
Neuroblastoma cells highly express the disialoganglioside GD2, a tumor-associated carbohydrate antigen, which is also expressed in neurons, skin melanocytes, and peripheral nerve fibers. Immunotherapy with monoclonal anti-GD2 antibodies has a proven
Externí odkaz:
https://doaj.org/article/1a56ce1878e541dabea9dfab3d25bdc7
Autor:
Fulvia Farabegoli, Andreia Granja, Joana Magalhães, Stefania Purgato, Manuela Voltattorni, Marina Pinheiro
Publikováno v:
ACS Omega. 7:41872-41881
The anticancer act i v i t y of epigallocatechin-3-gallate (EGCG), orally administrated, is limited by poor bioavailabi l i t y , absorption, and unpredictable distribution in human tissues. EGCG charged nanoparticles may represent an opportunity to
Autor:
Ottavio Gandolfi, Manuela Voltattorni, Roberto Rimondini, Rossella Dall'Olio, Federica Locchi
Publikováno v:
Behavioural Pharmacology. 16:635-642
This study aimed to evaluate the possible potentiating action of ionotropic or metabotropic (metabotropic glutamate receptor type 5) glutamate agonists on pharmacological effects induced in rats by the atypical antipsychotic olanzapine. The administr
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 367:615-620
Antipsychotic drugs reportedly show a common property in facilitating glutamatergic transmission in rat cerebral cortex. Since the binding of the radiolabelled channel blocker [3H]-MK801 is generally considered an affordable index of N-methyl-d-aspar
Autor:
Alessandro Poli, Manuela Voltattorni, Claudio Pietra, Rossella Dall'Olio, Gino Villetti, Ottavio Gandolfi, Veronica Bonfante
Publikováno v:
Pharmacology Biochemistry and Behavior. 70:157-166
Following intraperitoneal or oral administrations, CHF 3381 ([n-(2-indanyl)-glycinamide hydrochloride]) protected rats against maximal electroshock (MES) test seizures. As glutamatergic pathways play a pivotal role in epilepsy, to better characterize
Autor:
Elisabetta Ciani, Antonio Contestabile, Manuela Voltattorni, Lena Grøneng, Veslemøy Rolseth, Ragnhild E. Paulsen
Publikováno v:
Brain Research. 728:1-6
Glutamate kills sensitive neurons through several steps downstream to receptor activation: increased free Ca2+ levels, activation of various enzymes and accumulation of reactive oxygen species (ROS). We have evaluated in a well established model of n
Autor:
Giampaolo Ugolini, Giancarlo Rosati, Mario Taffurelli, Manuela Voltattorni, Mattia Lauriola, Gabriella Mattei, Isacco Montroni, Stefano Rivetti, Annalisa Palmieri, Desiree Martini, Marco Franchi, Claudio Ceccarelli, Rossella Solmi, Michele Bianchini
Publikováno v:
Scopus-Elsevier
Cross-Reacting Material 197 (CRM197) is a diphtheria toxin non-toxic mutant that has shown antitumor activity in mice and humans. It is still unclear whether this anti-tumorigenic effect depends on its strong inflammatory-immunological property, its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1387cae1c55b126a462e63ab8612b8c
http://hdl.handle.net/11585/106256
http://hdl.handle.net/11585/106256
Autor:
Enza Barbieri, Giovanna Cenacchi, Tiziano Di Tomaso, Roberta Salaroli, Manuela Voltattorni, Stefano Rivetti, Alice Ronchi, Silvia Cammelli, Claudio Ceccarelli, Felice Giangaspero, Elena Della Bella
Lithium is the main therapeutic agent for the treatment of bipolar disorders but nerve cells are not the sole target of this drug. Indeed, lithium has been reported to target numerous cell types and to affect cell proliferation, differentiation and d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d20e3f5fa7316448280a498ec4d0e30b
http://hdl.handle.net/11585/96084
http://hdl.handle.net/11585/96084
Autor:
Giampaolo Ugolini, Domenico Coppola, Rossella Solmi, Desiree Martini, Mirko Francesconi, Mario Taffurelli, Mattia Lauriola, Giancarlo Rosati, Furio Pezzetti, Alessandro Ruggeri, Manuela Voltattorni, Donatella Santini, Simone Zanotti, Isacco Montroni, Pierluigi Strippoli, Lia Guidotti, Gastone Castellani, Gabriella Mattei, Claudio Ceccarelli
Publikováno v:
BMC Cancer, Vol 8, Iss 1, p 227 (2008)
BMC Cancer
BMC Cancer
Background EGFR is frequently overexpressed in colon cancer. We characterized HT-29 and Caco-2, human colon cancer cell lines, untreated and treated with cetuximab or gefitinib alone and in combination with EGF. Methods Cell growth was determined usi