Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Manuela Trabi"'
Autor:
Frank Madaras, Peter Mirtschin, John de Jersey, Kong-Nan Zhao, Amanda Nouwens, Luke W. Guddat, Qianyun Sharon Du, Martin F. Lavin, Renee S. Richards, Manuela Trabi, Paul P. Masci
Publikováno v:
Toxicon. 111:37-49
Pseudechis australis is one of the most venomous and lethal snakes in Australia. Numerous phospholipase A2 (PLA2) isoforms constitute a major portion of its venom, some of which have previously been shown to exhibit not only enzymatic, but also haemo
Publikováno v:
Metabolomics. 9:1041-1047
Freezers in research institutions often contain a plethora of samples left over from studies performed years or even decades ago. Along with samples stored in biobanks, these could prove to be treasure troves for metabonomic research. Although the in
Autor:
John de Jersey, Renee S. Richards, Martin F. Lavin, Paul P. Masci, Manuela Trabi, Lambro A. Johnson, Liam St. Pierre
Publikováno v:
Biochimie. 93:659-668
Snake venoms contain a complex mixture of polypeptides that modulate prey homeostatic mechanisms through highly specific and targeted interactions. In this study we have identified and characterised cystatin-like cysteine-protease inhibitors from ela
Autor:
Paul P. Masci, Stephen T.H. Earl, Martin F. Lavin, Manuela Trabi, John de Jersey, Jonathan P. Robson
Publikováno v:
Biochimie. 93:519-527
C-type lectins are calcium-dependent sugar binding proteins and are distributed ubiquitously amongst vertebrate organisms. As part of a wider study on Australian snake venom components, we have identified and characterised a C-type lectin from the ve
Autor:
Lambro A. Johnson, Roscoe L. Warner, John de Jersey, Simone Flight, Patrick J. Gaffney, Paul P. Masci, Qianyun S Du, Martin F. Lavin, Manuela Trabi
Publikováno v:
British Journal of Haematology. 145:207-211
Aprotinin has been used widely in surgery as an anti-bleeding agent but is associated with a number of side effects. We report that textilinin-1, a serine protease inhibitor from Pseudonaja textilis venom with sequence relatedness to aprotinin, is a
Autor:
Manuela Trabi, David J. Craik
Publikováno v:
The Plant Cell. 16:2204-2216
The plant cyclotides are a family of 28 to 37 amino acid miniproteins characterized by their head-to-tail cyclized peptide backbone and six absolutely conserved Cys residues arranged in a cystine knot motif: two disulfide bonds and the connecting bac
Autor:
Lars Bohlin, Ulf Göransson, Anders Herrmann, Manuela Trabi, Erika Svangård, David J. Craik, Per Claeson
Publikováno v:
Journal of Natural Products. 67:806-810
Cyclotides, a family of approximately 50 mini-proteins isolated from various Violaceae and Rubiaceae plants, are characterized by their circular peptide backbone and six conserved cysteine residues arranged in a cystine knot motif. Cyclotides show a
Publikováno v:
Journal of Bacteriology. 185:4011-4021
Bacteria produce a wide variety of both proteinaceous and nonproteinaceous molecules for defense, mediation of microbial competitions, and signaling purposes. Of the protein-based molecules, there are examples of large folded polypeptides that are tr
Autor:
Manuela Trabi, David J. Craik
Publikováno v:
Trends in Biochemical Sciences. 27:132-138
Circular proteins are a recently discovered phenomenon. They presumably evolved to confer advantages over ancestral linear proteins while maintaining the intrinsic biological functions of those proteins. In general, these advantages include a reduced
Publikováno v:
Journal of Organometallic Chemistry. 493:33-40
A simple way for the preparation of undecamethylcyclohexasilanylalkalimetal compounds is described by the reaction of dodecamethylcyclohexasilane with alkalimetal alcoholats in glyme solvents. Reactions of other cyclosilanes are also discussed. Some