Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Manuela Sushnitha"'
Autor:
Christian A. Boada, Assaf Zinger, Scott Rohen, Jonathan O. Martinez, Michael Evangelopoulos, Roberto Molinaro, Madeleine Lu, Ramiro Alejandro Villarreal-Leal, Federica Giordano, Manuela Sushnitha, Enrica De Rosa, Jens B. Simonsen, Sergey Shevkoplyas, Francesca Taraballi, Ennio Tasciotti
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Apolipoprotein-based drug delivery is a promising approach to develop safe nanoparticles capable of targeted drug delivery for various diseases. In this work, we have synthesized a lipid-based nanoparticle (NPs) that we have called “Aposomes” pre
Externí odkaz:
https://doaj.org/article/1431445ef19540ffbdf36c33e227fd00
Autor:
Assaf Zinger, Caroline Cvetkovic, Manuela Sushnitha, Tomoyuki Naoi, Gherardo Baudo, Morgan Anderson, Arya Shetty, Nupur Basu, Jennifer Covello, Ennio Tasciotti, Moran Amit, Tongxin Xie, Francesca Taraballi, Robert Krencik
Publikováno v:
Advanced Science, Vol 8, Iss 19, Pp n/a-n/a (2021)
Abstract Nanovesicles (NVs) are emerging as innovative, theranostic tools for cargo delivery. Recently, surface engineering of NVs with membrane proteins from specific cell types has been shown to improve the biocompatibility of NVs and enable the in
Externí odkaz:
https://doaj.org/article/8dbc12c8f94d40c4983b4dc6fa2d3ecc
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Nanoparticle-based drug delivery systems have been synthesized from a wide array of materials. The therapeutic success of these platforms hinges upon their ability to favorably interact with the biological environment (both systemically and locally)
Externí odkaz:
https://doaj.org/article/2424866613934b72801573a4c64fd426
Autor:
Assaf Zinger, Ava Brozovich, Anna Pasto, Manuela Sushnitha, Jonathan O. Martinez, Michael Evangelopoulos, Christian Boada, Ennio Tasciotti, Francesca Taraballi
Publikováno v:
Nanomaterials, Vol 10, Iss 11, p 2172 (2020)
Efficient communication is essential in all layers of the biological chain. Cells exchange information using a variety of signaling moieties, such as small molecules, proteins, and nucleic acids. Cells carefully package these messages into lipid comp
Externí odkaz:
https://doaj.org/article/810ce7d3306e42db9f43bb023b776047
Autor:
Enrica De Rosa, Francesca Taraballi, Jenny C. Chang, Assaf Zinger, Tomoyuki Naoi, Gherardo Baudo, Manuela Sushnitha, Ennio Tasciotti
Publikováno v:
ACS Nano
Biomimetic nanoparticles aim to effectively emulate the behavior of either cells or exosomes. Leukocyte-based biomimetic nanoparticles, for instance, incorporate cell membrane proteins to transfer the natural tropism of leukocytes to the final delive
Autor:
Tomoyuki Naoi, Ennio Tasciotti, Manuela Sushnitha, Barry H. Trachtenberg, John P. Cooke, Roman A. Sukhovershin, Roberto Molinaro, Assaf Zinger, Christian Boada, Jonathan O. Martinez, Kelly A. Hartman, Picheng Zhao, Christopher Tsao
Publikováno v:
Circulation Research. 126:25-37
Rationale: Through localized delivery of rapamycin via a biomimetic drug delivery system, it is possible to reduce vascular inflammation and thus the progression of vascular disease. Objective: Use biomimetic nanoparticles to deliver rapamycin to the
Autor:
Iman K. Yazdi, Nupur Basu, Anna Pastò, Armando Torres, Ennio Tasciotti, Alessandro Parodi, Manuela Sushnitha, Stefania Acciardo, Jonathan O. Martinez, Sarah Hmaidan, Federica Giordano, Michael Evangelopoulos, Roberto Palomba
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Despite recent advances in drug delivery, the targeted treatment of unhealthy cells or tissues continues to remain a priority. In cancer (much like other pathologies), delivery vectors are designed to exploit physical and biological features of unhea
Autor:
Robert Krencik, Gherardo Baudo, Manuela Sushnitha, Jennifer Covello, Tomoyuki Naoi, Moran Amit, Francesca Taraballi, Caroline Cvetkovic, Ennio Tasciotti, Arya Shetty, Assaf Zinger, Nupur Basu, Morgan Anderson, Tongxin Xie
Publikováno v:
Adv Sci (Weinh)
Humanized Biomimetic Nanovesicles In article number 2101437, Assaf Zinger, Francesca Taraballi, Robert Krencik, and co‐workers optimize and validate the scalable production of neuron‐targeting biomimetic nanovesicles (NV) with distinct lipid back
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::603e27b7c8e234d3a5124c1dd6ff46d4
https://europepmc.org/articles/PMC8498856/
https://europepmc.org/articles/PMC8498856/
Autor:
Christian Boada, Assaf Zinger, Michael Evangelopoulos, Jonathan O. Martinez, Anna Pastò, Manuela Sushnitha, Ava Brozovich, Francesca Taraballi, Ennio Tasciotti
Publikováno v:
Nanomaterials
Nanomaterials, Vol 10, Iss 2172, p 2172 (2020)
Nanomaterials, Vol 10, Iss 2172, p 2172 (2020)
Efficient communication is essential in all layers of the biological chain. Cells exchange information using a variety of signaling moieties, such as small molecules, proteins, and nucleic acids. Cells carefully package these messages into lipid comp
Autor:
Jonathan O. Martinez, Alessandro Parodi, Roberto Molinaro, Claudia Corbo, Noemi Arrighetti, Manuela Sushnitha, Michael Evangelopoulos, Ennio Tasciotti
Publikováno v:
Biomaterials. 147:155-168
The engineering of future generations of nanodelivery systems aims at the creation of multifunctional vectors endowed with improved circulation, enhanced targeting and responsiveness to the biological environment. Moving past purely bio-inert systems