Circulating bilirubin levels and risk of colorectal cancer: serological and Mendelian randomization analyses

Autor: Nazlisadat Seyed Khoei, Mazda Jenab, Neil Murphy, Barbara L. Banbury, Robert Carreras-Torres, Vivian Viallon, Tilman Kühn, Bas Bueno-de-Mesquita, Krasimira Aleksandrova, Amanda J. Cross, Elisabete Weiderpass, Magdalena Stepien, Andrew Bulmer, Anne Tjønneland, Marie-Christine Boutron-Ruault, Gianluca Severi, Franck Carbonnel, Verena Katzke, Heiner Boeing, Manuela M. Bergmann, Antonia Trichopoulou, Anna Karakatsani, Georgia Martimianaki, Domenico Palli, Giovanna Tagliabue, Salvatore Panico, Rosario Tumino, Carlotta Sacerdote, Guri Skeie, Susana Merino, Catalina Bonet, Miguel Rodríguez-Barranco, Leire Gil, Maria-Dolores Chirlaque, Eva Ardanaz, Robin Myte, Johan Hultdin, Aurora Perez-Cornago, Dagfinn Aune, Konstantinos K. Tsilidis, Demetrius Albanes, John A. Baron, Sonja I. Berndt, Stéphane Bézieau, Hermann Brenner, Peter T. Campbell, Graham Casey, Andrew T. Chan, Jenny Chang-Claude, Stephen J. Chanock, Michelle Cotterchio, Steven Gallinger, Stephen B. Gruber, Robert W. Haile, Jochen Hampe, Michael Hoffmeister, John L. Hopper, Li Hsu, Jeroen R. Huyghe, Mark A. Jenkins, Amit D. Joshi, Ellen Kampman, Susanna C. Larsson, Loic Le Marchand, Christopher I. Li, Li Li, Annika Lindblom, Noralane M. Lindor, Vicente Martín, Victor Moreno, Polly A. Newcomb, Kenneth Offit, Shuji Ogino, Patrick S. Parfrey, Paul D. P. Pharoah, Gad Rennert, Lori C. Sakoda, Clemens Schafmayer, Stephanie L. Schmit, Robert E. Schoen, Martha L. Slattery, Stephen N. Thibodeau, Cornelia M. Ulrich, Franzel J. B. van Duijnhoven, Korbinian Weigl, Stephanie J. Weinstein, Emily White, Alicja Wolk, Michael O. Woods, Anna H. Wu, Xuehong Zhang, Pietro Ferrari, Gabriele Anton, Annette Peters, Ulrike Peters, Marc J. Gunter, Karl-Heinz Wagner, Heinz Freisling

Publikováno v: BMC Medicine, Vol 18, Iss 1, Pp 1-15 (2020)

Abstract Background Bilirubin, a byproduct of hemoglobin breakdown and purported anti-oxidant, is thought to be cancer preventive. We conducted complementary serological and Mendelian randomization (MR) analyses to investigate whether alterations in

Externí odkaz: https://doaj.org/article/cae0c18ed8fa4e30b56431b7e54f5dd8

Prediction of Circulating Adipokine Levels Based on Body Fat Compartments and Adipose Tissue Gene Expression

Autor: Stefan Konigorski, Jürgen Janke, Dagmar Drogan, Manuela M. Bergmann, Johannes Hierholzer, Rudolf Kaaks, Heiner Boeing, Tobias Pischon

Publikováno v: Obesity Facts, Pp 1-16 (2019)

Background: Adipokines are hormones secreted from adipose tissue (AT), and a number of them have been established as risk factors for chronic diseases. However, it is not clear whether and to what extent adiposity, gene expression, and other factors

Externí odkaz: https://doaj.org/article/bf2e0ad1abeb404f84c0684066bb36fe

Lifestyle factors for the prevention of inflammatory bowel disease

Autor: Emily W, Lopes, Simon S M, Chan, Mingyang, Song, Jonas F, Ludvigsson, Niclas, Håkansson, Paul, Lochhead, Allan, Clark, Kristin E, Burke, Ashwin N, Ananthakrishnan, Amanda J, Cross, Domenico, Palli, Manuela M, Bergmann, James M, Richter, Andrew T, Chan, Ola, Olén, Alicja, Wolk, Hamed, Khalili, Nick, Wareham

Publikováno v: Lopes, E W, Chan, S S M, Song, M, Ludvigsson, J F, Håkansson, N, Lochhead, P, Clark, A, Burke, K E, Ananthakrishnan, A N, Cross, A J, Palli, D, Bergmann, M M, Richter, J M, Chan, A T, Olén, O, Wolk, A, Khalili, H & EPIC-IBD investigators (Anja Viendahl Olsen, Kim Overvad; members) 2023, ' Lifestyle factors for the prevention of inflammatory bowel disease ', Gut, vol. 72, no. 6, pp. 1093-1100 . https://doi.org/10.1136/gutjnl-2022-328174

ObjectiveTo estimate the proportion of cases of Crohn’s disease (CD) and ulcerative colitis (UC) that could be prevented by modifiable lifestyle factors.DesignIn a prospective cohort study of US adults from the Nurses’ Health Study (NHS; n=72 290

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d700a9a14e252568d35f26819d6174
https://doi.org/10.1136/gutjnl-2022-328174

Co-benefits from sustainable dietary shifts for population and environmental health: an assessment from a large European cohort study

Autor: Manuela M. Bergmann, Tammy Y.N. Tong, Anna Stubbendorff, Elisabeth H. M. Temme, Claudia Agnoli, Ulrika Ericson, Antonio Agudo, Mélanie Deschasaux, Elisabete Weiderpass, Konstantinos K. Tsilidis, Dagfinn Aune, Guri Skeie, Giovanna Masala, Torkjel M. Sandanger, Emmanuelle Kesse-Guyot, Gianluca Severi, Charlotta Rylander, Francesca Mancini, Miguel A. Rodríguez Barranco, Marie-Christine Boutron-Ruault, Paolo Vineis, Mathilde Touvier, Pietro Ferrari, Marc J. Gunter, Daniel B Ibsen, Jolanda M. A. Boer, María José Pérez, Inge Huybrechts, Matthias B. Schulze, Anika Knuppel, Keren Papier, Elio Riboli, Bernard Srour, Christina C. Dahm, Jessica E. Laine, Tilmann Kühn

Publikováno v: e796
e786
Laine, J E, Huybrechts, I, Gunter, M J, Ferrari, P, Weiderpass, E, Tsilidis, K, Aune, D, Schulze, M B, Bergmann, M, Temme, E H M, Boer, J M A, Agnoli, C, Ericson, U, Stubbendorff, A, Ibsen, D B, Dahm, C C, Deschasaux, M, Touvier, M, Kesse-Guyot, E, Sánchez Pérez, M-J, Rodríguez Barranco, M, Tong, T Y N, Papier, K, Knuppel, A, Boutron-Ruault, M-C, Mancini, F, Severi, G, Srour, B, Kühn, T, Masala, G, Agudo, A, Skeie, G, Rylander, C, Sandanger, T M, Riboli, E & Vineis, P 2021, ' Co-benefits from sustainable dietary shifts for population and environmental health : an assessment from a large European cohort study ', The Lancet Planetary Health, vol. 5, no. 11, pp. e786-e796 . https://doi.org/10.1016/S2542-5196(21)00250-3
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Lancet Planetary Health
Lancet Planetary Health, Elsevier, 2021, 5 (11), pp.e786-e796. ⟨10.1016/S2542-5196(21)00250-3⟩
Laine, Jessica E; Huybrechts, Inge; Gunter, Marc J; Ferrari, Pietro; Weiderpass, Elisabete; Tsilidis, Kostas; Aune, Dagfinn; Schulze, Matthias B; Bergmann, Manuela; Temme, Elisabeth H M; Boer, Jolanda M A; Agnoli, Claudia; Ericson, Ulrika; Stubbendorff, Anna; Ibsen, Daniel B; Dahm, Christina Catherine; Deschasaux, Mélanie; Touvier, Mathilde; Kesse-Guyot, Emmanuelle; Sánchez Pérez, Maria-Jose; ... (2021). Co-benefits from sustainable dietary shifts for population and environmental health: an assessment from a large European cohort study. Lancet planetary health, 5(11), e786-e796. Elsevier 10.1016/S2542-5196(21)00250-3
Dipòsit Digital de la UB
Universidad de Barcelona
Lancet Planetary Health, 2021, 5 (11), pp.e786-e796. ⟨10.1016/S2542-5196(21)00250-3⟩

Funding European Commission (DG-SANCO) , the International Agency for Research on Cancer (IARC) , MRC Early Career Fellowship (MR/M501669/1) .
Background Unhealthy diets, the rise of non-communicable diseases, and the declining health of the pla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec94eb6aa5807be3aa1f53cc89a69d62
https://doi.org/10.1016/s2542-5196(21)00250-3

Identification of novel genes whose expression in adipose tissue affects body fat mass and distribution: an RNA-Seq and Mendelian Randomization study

Autor: Stefan Konigorski, Jürgen Janke, Giannino Patone, Manuela M. Bergmann, Christoph Lippert, Norbert Hübner, Rudolf Kaaks, Heiner Boeing, Tobias Pischon

Many studies have shown that abdominal adiposity is more strongly related to health risks than peripheral adiposity. However, the underlying pathways are still poorly understood. In this cross-sectional study using data from RNA-sequencing experiment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a08b36356bcdaf24c47d91a529d0aa0
http://edoc.mdc-berlin.de/22012/7/22012suppl.zip