Epistemological experience in developing of biomolecular technology for immunogene therapy strategy

Autor: Tatiana Castillo, Annabelle Trojan, Maria Claudia Noguera, Lina Manuela Jay, Cecilia Crane, Alexander Shevelev, Alvaro Alvarez, Heliodor Kasprzak, Gonzalo Melo, Pedro Jose Penagos, Beatriz Helena Aristizabal, Ignacio Briceño, Adis Ayala, Huynh T. Duc, Jerzy Trojan

Publikováno v: Revista Científica, Vol 2, Iss 25, Pp 228-240 (2016)

We have been faced with a 40 year long challenge: how to establish tools that can be applied in the treatment of brain tumor - glioblastoma (100% fatal) - using our knowledge of evolution, chemistry of proteins, genetics, molecular biology and immuno

Externí odkaz: https://doaj.org/article/95c04fbb25b9426180c27b4eb3e78201

Differential effects of chaperones on yeast prions: CURrent view

Autor: Lina Manuela Jay-Garcia, Andrew G. Matveenko, Yury O. Chernoff, Galina A. Zhouravleva, Yury A. Barbitoff

Publikováno v: Current Genetics. 64:317-325

Endogenous yeast amyloids that control heritable traits and are frequently used as models for human amyloid diseases are termed yeast prions. Yeast prions, including the best studied ones ([PSI +] and [URE3]), propagate via intimate interactions with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7699e7f70dda1125b92246c7f577e1c1
https://doi.org/10.1007/s00294-017-0750-3

Role of the Cell Asymmetry Apparatus and Ribosome-Associated Chaperones in the Destabilization of a

Autor: Rebecca L, Howie, Lina Manuela, Jay-Garcia, Denis A, Kiktev, Quincy L, Faber, Margaret, Murphy, Katherine A, Rees, Numera, Sachwani, Yury O, Chernoff

Publikováno v: Genetics

Self-perpetuating transmissible protein aggregates, termed prions, are implicated in mammalian diseases and control phenotypically detectable traits in Saccharomyces cerevisiae. Yeast stress-inducible chaperone proteins, including Hsp104 and Hsp70-Ss

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ccf98988b5f057b8c03fb08cb9add7df
https://pubmed.ncbi.nlm.nih.gov/31142614

β-Galactosidase Deficiency in Colombia: Report of 20 Patients Detected Using Dried Blood Spot Samples

Autor: Isidro Arevalo, Adis Ayala, Natalia Pacheco, Lina Manuela Jay Garcia, Monica España, Alfredo Uribe

Publikováno v: Journal of Inborn Errors of Metabolism and Screening v.3 2015
Journal of Inborn Errors of Metabolism and Screening
Instituto Genética para Todos (IGPT)
instacron:IGPT

β-Galactosidase (BGal) is the first enzyme involved in the catabolism of sphingolipids. Two pathologies have been directly associated with its deficiency: GM1 gangliosidosis and Morquio B. Morquio B is among the rarest types of mucopolysaccharidosis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::645533543a258df816ab1305962fb50b
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2326-45942015000100353

IGF-I biomarker testing in an ethical context

Autor: Tatiana Castillo, Annabelle Trojan, Pedro Penagos, Beatriz H. Aristizabal, Jerzy Trojan, Lina Manuela Jay, Ignacio Briceño

Publikováno v: Advances in Modern Oncology Research, Vol 2, Iss 4, Pp 188-200 (2016)

As we have come to know, there is a connection between cancer biomarkers and genes, along with their susceptibility to a particular disease, all of which have an obvious impact on the clinical practice and development of genetic testing. In any cance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5f5628096655aa52160900a046c3311
https://doi.org/10.18282/amor.v2.i4.58