Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Manuela Gridling"'
Autor:
Branka Radic-Sarikas, Uwe Rix, Alexey Stukalov, Manuela Gridling, André C. Müller, Jacques Colinge, Giulio Superti-Furga, Keiryn L. Bennett
Publikováno v:
EuPA Open Proteomics, Vol 9, Iss , Pp 43-53 (2015)
Gel-free liquid chromatography mass spectrometry coupled to chemical proteomics is a powerful approach for characterizing cellular target profiles of small molecules. We have previously described a fast and efficient elution protocol; however, altere
Externí odkaz:
https://doaj.org/article/09dd7702e75c46d5b27bebc9dcaba4dd
Autor:
Uwe Rix, Jacques Colinge, Katharina Blatt, Manuela Gridling, Lily L Remsing Rix, Katja Parapatics, Sabine Cerny-Reiterer, Thomas R Burkard, Ulrich Jäger, Junia V Melo, Keiryn L Bennett, Peter Valent, Giulio Superti-Furga
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77155 (2013)
Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) is in part driven by the tyrosine kinase bcr-abl, but imatinib does not produce long-term remission. Therefore, second-generation ABL inhibitors are currently in clinical investi
Externí odkaz:
https://doaj.org/article/71bb1f7bea894117aa5e71d83b77d809
Autor:
Uwe Rix, Keiryn L. Bennett, Giulio Superti-Furga, Jarrod A. Marto, Eric B. Haura, Jacques Colinge, Katja Parapatics, Lanxi Song, Florian P. Breitwieser, Scott B. Ficarro, Manuela Gridling
Table S1. Mutational status of all specimens regarding KRAS and EGFR.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0558ee243093eb10b379e99d8337928b
https://doi.org/10.1158/1535-7163.22501750
https://doi.org/10.1158/1535-7163.22501750
Autor:
Uwe Rix, Keiryn L. Bennett, Giulio Superti-Furga, Jarrod A. Marto, Eric B. Haura, Jacques Colinge, Katja Parapatics, Lanxi Song, Florian P. Breitwieser, Scott B. Ficarro, Manuela Gridling
Legends for Supplementary Figures and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad27c05d4ad01847a6b6a1f6db2d6b8c
https://doi.org/10.1158/1535-7163.22501753.v1
https://doi.org/10.1158/1535-7163.22501753.v1
Autor:
Uwe Rix, Keiryn L. Bennett, Giulio Superti-Furga, Jarrod A. Marto, Eric B. Haura, Jacques Colinge, Katja Parapatics, Lanxi Song, Florian P. Breitwieser, Scott B. Ficarro, Manuela Gridling
Figure S1. Cross-docking of sunitinib and dasatinib in NQO2 and PDXK.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83313c2b1d59069df2bbc1af23aae775
https://doi.org/10.1158/1535-7163.22501759
https://doi.org/10.1158/1535-7163.22501759
Autor:
Uwe Rix, Keiryn L. Bennett, Giulio Superti-Furga, Jarrod A. Marto, Eric B. Haura, Jacques Colinge, Katja Parapatics, Lanxi Song, Florian P. Breitwieser, Scott B. Ficarro, Manuela Gridling
A growing number of gene mutations, which are recognized as cancer drivers, can be successfully targeted with drugs. The redundant and dynamic nature of oncogenic signaling networks and complex interactions between cancer cells and the microenvironme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69de964373b89e60639ecede13aca671
https://doi.org/10.1158/1535-7163.c.6536884.v1
https://doi.org/10.1158/1535-7163.c.6536884.v1
Autor:
Sara Sdelci, Tibor Harkany, Keiryn L. Bennett, Kilian Huber, Patrick Collombat, Christian Honoré, Florian M. Pauler, Matthias Farlik, Ekaterine Berishvili, Monica Courtney, Igor Baburin, Stefan Kubicek, Nicole Schmitner, Jin Li, Steffen Hering, Peter Májek, Jacob Hecksher-Sørensen, Thierry Sulpice, Martin Distel, Robin A. Kimmel, Charles-Hugues Lardeau, Manuela Gridling, Johanna Klughammer, Camilla Ingvorsen, Alexey Stukalov, Christoph Bock, Andhira Vieira, François Briand, Giulio Superti-Furga, Roman A. Romanov, Thomas Frogne, Dirk Meyer, Caterina Sturtzel, Thomas Penz, Fabio Avolio, Katja Parapatics, Jacques Colinge, Andreas Spittler, Charlotte Barbieux, Tamara Casteels
Publikováno v:
Cell
Cell, Elsevier, 2017, 168 (1-2), pp.86-100.e15. ⟨10.1016/j.cell.2016.11.010⟩
Cell, Vol. 168, No 1-2 (2017) pp. 86-100.e15
Cell, Elsevier, 2017, 168 (1-2), pp.86-100.e15. ⟨10.1016/j.cell.2016.11.010⟩
Cell, Vol. 168, No 1-2 (2017) pp. 86-100.e15
Summary Type 1 diabetes is characterized by the destruction of pancreatic β cells, and generating new insulin-producing cells from other cell types is a major aim of regenerative medicine. One promising approach is transdifferentiation of developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eebb27a89e331313da6daa3b1b61b868
https://hal.umontpellier.fr/hal-02284911
https://hal.umontpellier.fr/hal-02284911
Autor:
Katja Parapatics, Giulio Superti-Furga, Uwe Rix, Manuela Gridling, Ivo Chamrád, Soner Altiok, André C. Müller, Jacques Colinge, Alexey Stukalov, Eric B. Haura, Keiryn L. Bennett
Publikováno v:
Journal of Proteome Research. 12:4005-4017
While targeted therapy based on the idea of attenuating the activity of a preselected, therapeutically relevant protein has become one of the major trends in modern cancer therapy, no truly specific targeted drug has been developed and most clinical
Autor:
Giulio Superti-Furga, Jacques Colinge, Manuela Gridling, Florian Grebien, Uwe Rix, Scott M. Carlson, Florian P. Breitwieser, Peter Valent, Keiryn L. Bennett, Georg E. Winter, Martin Bilban, Forest M. White, André C. Müller, Karoline V. Gleixner
Publikováno v:
Nature Chemical Biology. 8:905-912
Occurrence of the BCR-ABL(T315I) gatekeeper mutation is among the most pressing challenges in the therapy of chronic myeloid leukemia (CML). Several BCR-ABL inhibitors have multiple targets and pleiotropic effects that could be exploited for their sy
Autor:
Michael Grusch, Georg Krupitza, Zsuzsanna Bago-Horvath, Nha T.P. Vo, Caroline Vonach, Sabine Bauer, Manuela Gridling, Philipp Saiko, Thomas Szekeres, Nicole Stark, Walter Jäger, Paul Probst, Monika Fritzer-Szekeres, Benedikt Giessrigl, Sibylle Madlener, Afschin Soleiman, Irene Herbacek
Publikováno v:
Carcinogenesis. 31:2074-2081
Estrogenic procarcinogenic effects of piceatannol (PIC) contrast reports about anticarcinogenic activities of PIC. To explain this contradiction, we investigated PIC in estrogen-dependent MCF-7 breast cancer cells and elucidated those cellular mechan