Zobrazeno 1 - 10
of 201
pro vyhledávání: '"Manuela G Neuman"'
Autor:
Lawrence Cohen, Manuela G Neuman
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 23, Iss 1 (2020)
Cannabis has been used for its medicinal purposes since ancient times. Its consumption leads to the activation of Cannabis receptors CB1 and CB2 that, through specific mechanisms can lead to modulation and progression of inflammation or repair. The n
Externí odkaz:
https://doaj.org/article/efde074647cc4199bf4ad5bc50cbcc1c
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 23, Iss 1 (2020)
Gamma glutamyl transferase (GGT) is an enzyme in glutathione and cysteine metabolism. GGT is a standard liver enzyme test reflecting biliary tract involvement. It also has a prooxoidant activity and a modulating influence on endothelia dysfunction. G
Externí odkaz:
https://doaj.org/article/c2a27558d5eb4189b4bf33911adaf817
Publikováno v:
Canadian Journal of Gastroenterology and Hepatology, Vol 29, Iss 5, Pp 241-252 (2015)
Unhealthy diet and lack of physical exercise are responsible for fat accumulation in the liver, which may lead to liver disease. Histologically, the severity of the disease has two stages: nonalcoholic fatty liver disease (NAFLD) and nonalcoholic ste
Externí odkaz:
https://doaj.org/article/fe50a507ff03457d9796f1d77a7cf380
Publikováno v:
Canadian Journal of Gastroenterology and Hepatology, Vol 28, Iss 11, Pp 607-618 (2014)
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is a chronic liver condition characterized by insulin resistance, type 2 diabetes and fat accumulation in the liver that may cause hepatic inflammation and progressive scarring leading to nonalcoho
Externí odkaz:
https://doaj.org/article/d183752f1170439fab66b0ce1e7e5d1e
Autor:
Manuela G Neuman, Mihai Voiculescu, Radu M Nanau, Yaakov Maor, Ehud Melzer, Lawrence B Cohen, Mihai Opris, Stephen Malnick
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 19, Iss 1 (2016)
The present review includes translational and clinical research that characterize non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). Clinical and experimental evidence led to the recognition of the key toxic role play
Externí odkaz:
https://doaj.org/article/36b31ee5be6b49c184e3a35d2b8508e1
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 18, Iss 4 (2015)
PURPOSE: This article aimed 1) to review herbal medicine containing pyrrolizidine alkaloids (PA)-induced toxicities of the liver; 2) to encourage the recognition and prevention of common problems encountered when using complementary and alternative m
Externí odkaz:
https://doaj.org/article/e28564655109461c9d2278b822bc6481
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 18, Iss 1 (2015)
Background. We developed an experimental model of ethanol-induced dermatotoxicity and hepatocytoxicity using normal human keratinocytes and normal human hepatocytes that preserve inducible cytochrome p450 activities. The original work was described i
Externí odkaz:
https://doaj.org/article/2562168cdd8849459a3151882b90ec1c
Autor:
Pearl Jacobson-Brown, Manuela G Neuman
Publikováno v:
Canadian Journal of Gastroenterology, Vol 18, Iss 4, Pp 239-249 (2004)
The progression from precancerous (adenomatous) colon polyps to malignant colorectal cancer involves the complex actions of various cytokines on T cell proliferation, cell-cell adhesion, apoptosis and host immunity. A broad spectrum of new treatments
Externí odkaz:
https://doaj.org/article/2fe0b2b5b6624b37a284e56387714822
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 17, Iss 4 (2014)
Background: Biological therapies using anti-tumor necrosis factor (TNF)-α agents have an important impact in the treatment of inflammatory bowel disease, rheumatoid arthritis, psoriasis, and other inflammatory conditions. However, a significant numb
Externí odkaz:
https://doaj.org/article/f6e92f293de541988eabe1d7a687bc6b
Autor:
Radu M Nanau, Manuela G Neuman
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 17, Iss 3 (2014)
Purpose. Inflammatory and rheumatic arthritis remain leading causes of disability worldwide. The arthritis therapeutic area commands the largest market for the prescription of biological and non-steroidal anti-inflammatory drugs (NSAID). Yet biotechn
Externí odkaz:
https://doaj.org/article/b3a439580f6d4592a099343e44e45e4e