Výsledky vyhledávání - "Manuela Capone"

Akademický článek

HPLC and flow cytometry combined approach for HbF analysis in fetomaternal haemorrhage evaluation

Autor: Benedetta Peruzzi, Serena Guerrieri, Tiziana Biagioli, Luisa Lanzilao, Sara Pratesi, Sara Bencini, Marinella Statello, Alessia Carraresi, Stefania Stefanelli, Martina Tonelli, Marco Brogi, Manuela Capone, Alessio Mazzoni, Anna Maria Grazia Gelli, Alessandra Fanelli, Roberto Caporale, Francesco Annunziato

Publikováno v: Practical Laboratory Medicine, Vol 40, Iss , Pp e00401- (2024)

Introduction: Recently, a flow cytometric (FC) based test has been developed for detection of circulating fetal cells to replace the less accurate and reproducible Kleihauer-Betke test.FC test is easier to perform, it can distinguish the origin of fe

Externí odkaz: https://doaj.org/article/30d6a8b42f4246a58029e6eacf19c735

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Akademický článek

Bendamustine impairs humoral but not cellular immunity to SARS-CoV-2 vaccination in rituximab-treated B-cell lymphoma–affected patients

Autor: Anna Vanni, Lorenzo Salvati, Alessio Mazzoni, Giulia Lamacchia, Manuela Capone, Stefania Francalanci, Seble Tekle Kiros, Lorenzo Cosmi, Benedetta Puccini, Manuel Ciceri, Benedetta Sordi, Gian Maria Rossolini, Francesco Annunziato, Laura Maggi, Francesco Liotta

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

BackgroundPatients with B-cell lymphoma are a fragile category of subjects, particularly exposed to infections and characterized by an impaired vaccination response due to the disease itself and, even more, to the chemotherapy regimen. For this reaso

Externí odkaz: https://doaj.org/article/2d129dd8ff754e8990e64224ad8fb630

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Akademický článek

Rapid evaluation of T cell clonality in the diagnostic work-up of mature T cell neoplasms: TRBC1-based flow cytometric assay experience

Autor: Manuela Capone, Benedetta Peruzzi, Boaz Palterer, Sara Bencini, Alessandro Sanna, Benedetta Puccini, Luca Nassi, Benedetta Salvadori, Marinella Statello, Alessia Carraresi, Stefania Stefanelli, Chiara Orazzini, Barbara Minuti, Roberto Caporale, Francesco Annunziato

Publikováno v: Translational Oncology, Vol 26, Iss , Pp 101552- (2022)

The identification of mature T cell neoplasms by flow cytometry is often challenging, due to overlapping features with reactive T cells and limitations of currently available T cell clonality assays. The description of an antibody specific for one of

Externí odkaz: https://doaj.org/article/0d65f29569414cb9a52d8b0b945183a5

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Akademický článek

Variants Disrupting CD40L Transmembrane Domain and Atypical X-Linked Hyper-IgM Syndrome: A Case Report With Leishmaniasis and Review of the Literature

Autor: Boaz Palterer, Lorenzo Salvati, Manuela Capone, Valentina Mecheri, Laura Maggi, Alessio Mazzoni, Lorenzo Cosmi, Nila Volpi, Lucia Tiberi, Aldesia Provenzano, Sabrina Giglio, Paola Parronchi, Giandomenico Maggiore, Oreste Gallo, Alessandro Bartoloni, Francesco Annunziato, Lorenzo Zammarchi, Francesco Liotta

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

X-linked hyper-IgM (XHIGM) syndrome is caused by mutations of the CD40LG gene, encoding the CD40L protein. The clinical presentation is characterized by early-onset infections, with profound hypogammaglobulinemia and often elevated IgM, susceptibilit

Externí odkaz: https://doaj.org/article/2e57030a27d244f1893271041a33dc56

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Akademický článek

SARS-CoV-2 infection and vaccination trigger long-lived B and CD4+ T lymphocytes with implications for booster strategies

Publikováno v: The Journal of Clinical Investigation, Vol 132, Iss 6 (2022)

BACKGROUND Immunization against SARS-CoV-2, the causative agent of COVID-19, occurs via natural infection or vaccination. However, it is currently unknown how long infection- or vaccination-induced immunological memory will last.METHODS We performed

Externí odkaz: https://doaj.org/article/de56b006ac5b4d2babea1679a8b108f5

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Akademický článek

SARS-CoV-2 Spike-Specific CD4+ T Cell Response Is Conserved Against Variants of Concern, Including Omicron

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Although accumulating data have investigated the effect of SARS-CoV-2 mutations on antibody neutralizing activity, less is known about T cell immunity. In this work, we found that the ancestral (Wuhan strain) Spike protein can efficaciously reactivat

Externí odkaz: https://doaj.org/article/7812720b794c41a697b682fef5958726

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Akademický článek

Fourth Dose of mRNA COVID-19 Vaccine Transiently Reactivates Spike-Specific Immunological Memory in People Living with HIV (PLWH)

Autor: Giulia Lamacchia, Lorenzo Salvati, Seble Tekle Kiros, Alessio Mazzoni, Anna Vanni, Manuela Capone, Alberto Carnasciali, Parham Farahvachi, Filippo Lagi, Nicoletta Di Lauria, Arianna Rocca, Maria Grazia Colao, Francesco Liotta, Lorenzo Cosmi, Gian Maria Rossolini, Alessandro Bartoloni, Laura Maggi, Francesco Annunziato

Publikováno v: Biomedicines, Vol 10, Iss 12, p 3261 (2022)

Background: People Living With HIV (PLWH), with advanced disease, lower CD4+ T cell counts or an unsuppressed HIV viral load can have a suboptimal vaccine response. For this reason, in the current COVID-19 pandemic, they represent a prioritized popul

Externí odkaz: https://doaj.org/article/fa75086f94244733a1b3def3d036dd77

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Akademický článek

T Cell Response Toward Tissue-and Epidermal-Transglutaminases in Coeliac Disease Patients Developing Dermatitis Herpetiformis

Autor: Marzia Caproni, Manuela Capone, Maria Caterina Rossi, Veronica Santarlasci, Laura Maggi, Alessio Mazzoni, Beatrice Rossettini, Daniela Renzi, Lavinia Quintarelli, Beatrice Bianchi, Alessandra Ninci, Gabriele Lami, Antonio Calabrò, Lorenzo Cosmi, Francesco Annunziato, Francesco Liotta

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

The reason why only few coeliac patients develop the cutaneous manifestation of the disease, named dermatitis herpetiformis (DH), is still unknown. Epidermal transglutaminase (TG3) has been described as the main autoantigen of humoral immunity in DH

Externí odkaz: https://doaj.org/article/f5a8e7966ce9450388f1ea2e2356825b

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